Invention Grant
- Patent Title: Didemnin biosynthetic gene cluster in Tistrella mobilis
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Application No.: US14346068Application Date: 2012-09-21
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Publication No.: US09644005B2Publication Date: 2017-05-09
- Inventor: Pei-Yuan Qian , Ying Sharon Xu , Pok-Yui Lai
- Applicant: King Abdullah University of Science and Technology
- Applicant Address: SA Thuwal
- Assignee: King Abdullah University of Science and Technology
- Current Assignee: King Abdullah University of Science and Technology
- Current Assignee Address: SA Thuwal
- Agency: Smith, Gambrell & Russell, LLP
- International Application: PCT/IB2012/002361 WO 20120921
- International Announcement: WO2013/041969 WO 20130328
- Main IPC: C07K11/02
- IPC: C07K11/02 ; C07K14/195 ; C12R1/01 ; C12P17/18 ; C12N15/52
Abstract:
A novel Tistrella mobilis strain having Accession Deposit Number NRRL B-50531 is provided. A method of producing a didemnin precursor, didemnin or didemnin derivative by using the Tistrella mobilis strain, and the therapeutic composition comprising at least one didemnin or didemnin derivative produced from the strain or modified strain thereof are also provided.
Public/Granted literature
- US20140296161A1 DIDEMNIN BIOSYNTHETIC GENE CLUSTER IN TISTRELLA MOBILIS Public/Granted day:2014-10-02
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