Embodiments of the present disclosure relate to methods and apparatuses for channel estimation and feedback in a three dimensional multiple input multiple output (3D-MIMO) system. A method may comprise: transmitting a plurality of reference signals for a plurality of columns in an antenna array; receiving indication information on configuration adjustment of a precoding information feedback, wherein the indication information is based on measurement on the plurality of reference signals; and adjusting a configuration of the precoding information feedback based on the indication information so that a multiple vertical precoding information feedback is enabled when it can obtain a performance gain. Especially, the multiple vertical precoding information feedback may represent feeding back a plurality of vertical precoding matrix indicators for the plurality of columns in the antenna array. In embodiments of the present disclosure, there is provided a new solution for channel estimation and feedback in a 3D-MIMO system, and it may achieve a more accurate beamforming and/or a higher order spatial multiplexing, thereby improving the performance of the 3D-MIMO system.