Invention Grant
- Patent Title: Small molecule inhibitors of polynucleotide kinase/phosphatase, poly(ADP-ribose) polymerase and uses thereof
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Application No.: US14701321Application Date: 2015-04-30
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Publication No.: US09694073B2Publication Date: 2017-07-04
- Inventor: Michael Weinfeld , Dennis G. Hall , Feridoun Karimi-Busheri , Gary Kenneth Freschauf , Todd Randall Mereniuk
- Applicant: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA , ALBERTA HEALTH SERVICES
- Applicant Address: CA Edmonton CA Edmonton
- Assignee: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA,ALBERTA HEALTH SERVICES
- Current Assignee: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA,ALBERTA HEALTH SERVICES
- Current Assignee Address: CA Edmonton CA Edmonton
- Agency: Acuity Law Group, PC
- Agent Michael Whittaker
- Main IPC: A61K31/44
- IPC: A61K31/44 ; C07D498/02 ; A61K41/00 ; A61K31/4375 ; A61K31/437 ; A61K31/4745 ; A61N5/10 ; C07D471/04
Abstract:
The present invention generally relates to use of compounds and compositions as a chemosensitizers and/or radiosensitizers and/or inhibitors of PNKP phosphatase activity. The present invention provides pharmaceutical combinations and/or a pharmaceutically acceptable salt thereof, kits containing such compounds and/composition and methods of using such compounds and/or compositions.
Public/Granted literature
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