Invention Grant
- Patent Title: TGFβR antagonists
-
Application No.: US14977709Application Date: 2015-12-22
-
Publication No.: US09708316B2Publication Date: 2017-07-18
- Inventor: Brian E. Fink , Yufen Zhao , Robert M. Borzilleri , Liping Zhang , Kyoung S. Kim , Muthoni G. Kamau , Andrew J. Tebben , Yong Zhang , Andrew F. Donnell
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Elliott Korsen
- Main IPC: A61K31/4709
- IPC: A61K31/4709 ; A61K31/501 ; C07D487/04 ; C07D471/04 ; A61K31/5377 ; A61K31/437 ; A61K31/496 ; A61K31/4985 ; A61K31/506 ; A61K31/541
Abstract:
The invention relates generally to compounds that modulate the activity of TGFβR-1 and TGFβR-2, pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
Public/Granted literature
- US20160176871A1 TGF BETA R ANTAGONISTS Public/Granted day:2016-06-23
Information query
IPC分类:
