Invention Grant
- Patent Title: Antibodies targeting HIV escape mutants
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Application No.: US13924469Application Date: 2013-06-21
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Publication No.: US09879068B2Publication Date: 2018-01-30
- Inventor: Ron Diskin , Anthony P. West , Michel C. Nussenzweig , Pamela J. Bjorkman
- Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY , The Rockefeller University
- Applicant Address: US CA Pasadena US NY New York
- Assignee: California Institute of Technology,The Rockefeller University
- Current Assignee: California Institute of Technology,The Rockefeller University
- Current Assignee Address: US CA Pasadena US NY New York
- Agency: Lewis Roca Rothgerber Christie LLP
- Main IPC: A61K39/42
- IPC: A61K39/42 ; C07K16/10 ; A61K39/00
Abstract:
Embodiments of the present invention are directed to compositions and methods for anti-HIV (anti-CD4 binding site) broadly neutralizing antibodies having improved potency and breadth for neutralizing a range of HIV strains. Combinations of broadly neutralizing antibodies can also improve potency over a single antibody composition.
Public/Granted literature
- US20140017234A1 ANTIBODIES TARGETING HIV ESCAPE MUTANTS Public/Granted day:2014-01-16
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