A method and apparatus for home Node-B (HNB) mobility with a local IP access (LIPA) packet data network (PDN) connection are described. A target home node-B (HNB) may receive a handover request message from a source HNB to handover a wireless transmit/receive unit (WTRU). A path switch request may be transmitted to a local gateway (LGW) to change a downlink data path towards the target HNB in response to the handover request message. The LGW may act as a mobility management and local mobility anchor for the handover; and informing an HNB gateway (GW) about the handover so that the downlink data path for core network (CN) traffic is modified towards the target HNB.