Invention Grant
- Patent Title: Compounds and methods for assaying redox state of metabolically active cells and methods for measuring NAD(P)/NAD(P)H
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Application No.: US14032420Application Date: 2013-09-20
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Publication No.: US09951372B2Publication Date: 2018-04-24
- Inventor: Wenhui Zhou , Jolanta Vidugiriene , Helene A. Benink , James J. Cali , Sarah Duellman , Dieter Klaubert , Donna Leippe , Martha O'Brien , John Shultz , Mary Sobol
- Applicant: PROMEGA CORPORATION
- Applicant Address: US WI Madison
- Assignee: PROMEGA CORPORATION
- Current Assignee: PROMEGA CORPORATION
- Current Assignee Address: US WI Madison
- Agency: Michael Best & Friedrich LLP
- Main IPC: C12Q1/32
- IPC: C12Q1/32 ; C12Q1/66 ; C07D417/04 ; C07D487/04 ; C07D493/10 ; C07D277/68 ; C07D497/10 ; C07F9/6558 ; C07F9/6561 ; G01N21/76 ; G01N33/50 ; G01N33/573 ; G01N33/58
Abstract:
The present invention provides compounds and methods for assaying redox state of metabolically active cells and methods for assaying enzyme activity and/or metabolite level by coupling to redox defining co-factor NAD(P)/NAD(P)H measurement.
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