A method and apparatus are described for a User Equipment (UE) to transmit in a control channel ACKnowledgement signals associated with a Hybrid Automatic Repeat reQuest process (HARQ-ACK signals) in response to receiving Transport Blocks (TBs) transmitted from a base station. The UE conveys the HARQ-ACK information by selecting one resource from multiple resources in the control channel and by selecting a constellation point of the modulation scheme for the HARQ-ACK signal. Transmission diversity is supported using different control channel resources that are already available to the UE without configuring additional resources. Design principles are described to optimally map the HARQ-ACK information to control channel resources and modulation constellation points for a Time Division Duplex (TDD) system and for a Frequency Division Duplex (FDD) system.