Invention Application
WO2006091567A2 HYDROXYALKYL SUBSTITUTED IMIDAZOQUINOLINE COMPOUNDS AND METHODS
审中-公开
羟基喹啉取代的咪唑啉醇化合物和方法
- Patent Title: HYDROXYALKYL SUBSTITUTED IMIDAZOQUINOLINE COMPOUNDS AND METHODS
- Patent Title (中): 羟基喹啉取代的咪唑啉醇化合物和方法
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Application No.: PCT/US2006006042Application Date: 2006-02-22
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Publication No.: WO2006091567A2Publication Date: 2006-08-31
- Inventor: KSHIRSAGAR TUSHAR A , MERRILL BRYON A , NIWAS SHRI , LUNDQUIST GREGORY D JR , HEPPNER PHILIP D , DANIELSON MICHAEL E
- Applicant: 3M INNOVATIVE PROPERTIES CO , KSHIRSAGAR TUSHAR A , MERRILL BRYON A , NIWAS SHRI , LUNDQUIST GREGORY D JR , HEPPNER PHILIP D , DANIELSON MICHAEL E
- Assignee: 3M INNOVATIVE PROPERTIES CO,KSHIRSAGAR TUSHAR A,MERRILL BRYON A,NIWAS SHRI,LUNDQUIST GREGORY D JR,HEPPNER PHILIP D,DANIELSON MICHAEL E
- Current Assignee: 3M INNOVATIVE PROPERTIES CO,KSHIRSAGAR TUSHAR A,MERRILL BRYON A,NIWAS SHRI,LUNDQUIST GREGORY D JR,HEPPNER PHILIP D,DANIELSON MICHAEL E
- Priority: US65549505 2005-02-23
- Main IPC: A61K31/355
- IPC: A61K31/355
Abstract:
Certain imidazoquinolines with a hydroxymethyl or hydroxyethyl substituent at the 2-position, and an aryl or heteroaryl substituent at the 7-position, pharmaceutical compositions containing the compounds, intermediates, methods of making and methods of use of these compounds as immunomodulators, for preferentially inducing IFN-a biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
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