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公开(公告)号：GB9917182D0
公开(公告)日：1999-09-22
申请号：GB9917182
申请日：1999-07-23
Applicant: ROSS STUART A , ROSS LIANNE J , ROSS ELIZABETH , ROSS ANDREW A
IPC: H02G3/04
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公开(公告)号：WO2004016749A3
公开(公告)日：2004-08-26
申请号：PCT/US0325389
申请日：2003-08-14
Applicant: PHARMACIA CORP , ROSS STUART A
Inventor： ROSS STUART A
CPC classification number: C12N15/1137 , A61K38/00 , C12N2310/315 , C12N2310/321 , C12N2310/3341 , C12N2310/341 , C12N2310/346 , C12Y602/01003 , Y02P20/582 , C12N2310/3521 , C12N2310/3525
Abstract: Antisense compounds, compositions, and methods are provided for modulating the expression of acyl-Coa synthesis 1, heretofore referred to as ACS1. The compositions comprise antisense compounds, particulary antisense oligonucleotides, targeted to nucleic acids encoding ACS1. Methods of using these compounds for modulation of ACS1 expression and for treatment of diseases associated with expression of ACS1 are provided.
Abstract translation: 提供反义化合物，组合物和方法用于调节前面称为ACS1的酰基辅酶A合成的表达。 组合物包含靶向编码ACS1的核酸的反义化合物，特异性反义寡核苷酸。 提供了使用这些化合物调节ACS1表达和治疗ACS1表达相关疾病的方法。
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公开(公告)号：WO2004016749A2
公开(公告)日：2004-02-26
申请号：PCT/US2003/025389
申请日：2003-08-14
Applicant: PHARMACIA CORPORATION , ROSS, Stuart, A.
Inventor： ROSS, Stuart, A.
IPC: C12N
CPC classification number: C12N15/1137 , A61K38/00 , C12N2310/315 , C12N2310/321 , C12N2310/3341 , C12N2310/341 , C12N2310/346 , C12Y602/01003 , Y02P20/582 , C12N2310/3521 , C12N2310/3525
Abstract: Antisense compounds, compositions, and methods are provided for modulating the expression of acyl-Coa synthesis 1, heretofore referred to as ACS1. The compositions comprise antisense compounds, particulary antisense oligonucleotides, targeted to nucleic acids encoding ACS1. Methods of using these compounds for modulation of ACS1 expression and for treatment of diseases associated with expression of ACS1 are provided.
Abstract translation: 提供反义化合物，组合物和方法用于调节酰基-CoA合成1（迄今称为ACS1）的表达。 该组合物包含靶向编码ACS1的核酸的反义化合物，特别是反义寡核苷酸。 提供了使用这些化合物调节ACS1表达和治疗与ACS1表达相关的疾病的方法。
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