-
公开(公告)号：WO2013180431A1
公开(公告)日：2013-12-05
申请号：PCT/KR2013/004642
申请日：2013-05-28
Applicant: 서울대학교산학협력단
CPC classification number: A61K35/19 , A61K35/12 , A61K35/16 , A61L27/3616 , A61L27/3834 , C12N5/0663 , C12N2500/84 , C12N2502/115
Abstract: 본 발명은 PRP(Platelet-Rich Plasma)를 유효성분으로 포함하는 세포 부착능 및 귀소능 증진용 조성물을 제공한다. 본 발명은 PRP를 유효성분으로 포함하는 조성물을 생체외 분리된 세포에 처리하는 단계를 포함하는 세포의 부착능 및 귀소 능을 개선하는 방법을 제공한다. 본 발명에 따르면, 이식하고자 하는 세포 또는 세포를 이식하고자 하는 부위에 PRP를 전처리하거나, PRP를 이식하고자 하는 세포와 혼합하여 생체내 부위에 이식하면 이식 부위에서 세포의 부착능이 증가하며, 이식 부위에서 손상부위로 세포의 귀소능이 증가한다.
Abstract translation: 本发明提供一种用于增强细胞移植和归巢性质的组合物，其含有富血小板血浆（PRP）作为活性成分。 本发明提供了一种改善细胞移植和归巢特性的方法，包括用含有PRP作为活性成分的组合物在体外分离细胞的处理步骤。 根据本发明，当用PRP处理要移植的细胞或移植细胞的区域或将待移植的细胞与PRP混合时，进行移植到体内区域，从而增加细胞移植 在移植区域和增加从移植区域到损伤区域的细胞归巢。
-
公开(公告)号：KR102207694B1
公开(公告)日：2021-01-26
申请号：KR1020190003742
申请日：2019-01-11
Applicant: 서울대학교산학협력단
Abstract: 본발명은골수내 내재성세포증식효과를갖는근골격계의질환예방또는치료용약학조성물에관한것이다. 보다상세하게는본 발명의약학조성물은골수내에서내재성세포를증식시키고기능을강화시킴으로써근골격계질환의치료용도로사용될수 있다.
-
公开(公告)号：KR101445322B1
公开(公告)日：2014-10-01
申请号：KR1020130072601
申请日：2013-06-24
Applicant: 서울대학교산학협력단
Inventor： 조현철
Abstract: Disclosed is a method for centrifugal separation which can centrifuge an object to be processed more simply and quickly. The method for centrifugal separation to centrifuge a target component from the object to be processed by centrifugal separation comprises: a step for storing the object to be processed inside a syringe in order for air space to be formed inside the syringe; a step for connecting a separation chamber which can change the volume to a nozzle of the syringe; a step for interlayer-separating the object to be processed into a first specific component, a boundary layer and a second specific component; a step for moving the boundary layer to the nozzle by mutually changing the volume of the syringe and the volume of the separation chamber; a step for spatially separating the first specific component and the boundary layer arranged in the separation chamber from the nozzle by using the air space; a step for separating the separation chamber where the first specific component is accommodated from the syringe; a step for performing second centrifugal separation of the second specific component and the boundary layer remaining in the syringe; and a step for discharging the second specific component arranged on the side of the nozzle by the second centrifugal separation through the nozzle.
Abstract translation: 公开了一种离心分离方法，其可以更简单和快速地离心待处理的物体。 离心分离离心分离方法是通过离心分离将待处理物体离心分离的方法，其特征在于，包括以下步骤：将注射器内的被处理物体储存在注射器的内部，以便在注射器内形成空气空间; 用于连接可以将体积改变到注射器的喷嘴的分离室的步骤; 用于将待处理物体层间分离为第一特定成分，边界层和第二特定成分的步骤; 通过相互改变注射器的体积和分离室的体积来将边界层移动到喷嘴的步骤; 通过使用空气空间将布置在分离室中的第一特定部件和边界层与喷嘴空间分离的步骤; 从所述注射器分离容纳所述第一特定成分的分离室的步骤; 用于进行第二特定成分和残留在注射器中的边界层的第二离心分离的步骤; 以及通过第二离心分离通过喷嘴排出布置在喷嘴侧的第二特定部件的步骤。
-
公开(公告)号：KR1020120140092A
公开(公告)日：2012-12-28
申请号：KR1020110059743
申请日：2011-06-20
Applicant: 서울대학교산학협력단
Inventor： 조현철
CPC classification number: A61M5/31511 , B04B5/02
Abstract: PURPOSE: A syringe for centrifugation and a centrifugation method are provided to prevent a syringe from infecting or deteriorating and to easily extract target components from an object to be extracted. CONSTITUTION: A syringe(200) for centrifugation includes a barrel(210) and a plunger(220). A nozzle is formed at one end part of the barrel, and the plunger is arranged at another end part of the barrel. The plunger is linearly movable in the barrel. The plunger ensures a path(260) through which the barrel is connected to a space in the head of the plunger. The syringe separates one material from another material in the barrel through the path.
Abstract translation: 目的：提供用于离心的注射器和离心方法以防止注射器感染或恶化，并且容易地从被提取物中提取目标成分。 构成：用于离心的注射器（200）包括筒体（210）和柱塞（220）。 在筒体的一个端部形成有喷嘴，并且柱塞布置在筒体的另一端部。 柱塞在筒中可线性移动。 柱塞确保了一个路径（260），筒体通过该路径连接到柱塞的头部中的空间。 注射器通过路径将一种材料与筒体中的另一种材料分开。
-
公开(公告)号：KR101043227B1
公开(公告)日：2011-06-21
申请号：KR1020100099123
申请日：2010-10-12
Applicant: 서울대학교산학협력단
Abstract: PURPOSE: A centrifugation method and syringe for centrifugation are provided to extract blood by using syringe and to pass centrifugation process immediately inside the syringe without the need do move blood to other reservoir or tube. CONSTITUTION: The centrifugation method includes the steps of: storing an processing object inside the syringe(S10); first centrifuging the processing object of inside of syringe in the state of arranging nozzle to face outside of the center of rotation(S20). Density relatively highs among the component comprising the processing object, task specific component, arranged at nozzle by the first centrifugation, is discharged through the nozzle(S30). The syringe is reversed so the nozzle face inside of the center of rotation of syringe and second centrifuges the processing object of inside of the syringe(S40). Density is relatively low among the remaining component comprising the processing object and the other specific component, arranged at the nozzle by the second centrifugation, is discharged through the nozzle(S50).
Abstract translation: 目的：提供离心方法和离心注射器，通过使用注射器提取血液，并在注射器内立即通过离心过程，无需将血液移动到其他储液器或管中。 构成：离心方法包括以下步骤：将处理对象存储在注射器内（S10）; 首先将喷嘴配置在旋转中心外侧的状态下离心注射器内部的加工对象（S20）。 在包括处理对象的部件，通过第一离心布置在喷嘴处的任务专用部件的部件中的密度相对较高通过喷嘴排出（S30）。 注射器反转，使得喷嘴面向注射器旋转中心的内侧，并且将注射器内部的处理对象离心（S40）。 通过喷嘴排出包括处理对象的剩余部件和布置在喷嘴处的第二离心部件的其他特定部件的密度相对较低（S50）。
-
Patent Agency Ranking
公开(公告)号：KR101043233B1
公开(公告)日：2011-06-21
申请号：KR1020100099128
申请日：2010-10-12
Applicant: 서울대학교산학협력단
Abstract: PURPOSE: A syringe is provided to restrain the arrangement of a plunger about a barrel through the self-structure of the syringe without a separate fixing device. CONSTITUTION: A syringe comprises: a barrel(110) in which a nozzle is formed in one end thereof; a plunger(120) which is received into the barrel in order to move in a straight line within the barrel; and a plunger manipulation unit(130) which is arranged in the other end part of the barrel, reciprocates with the plunger, and selectively restrains the arrangement of a plunger about a barrel. The plunger is linked with the reciprocating motion manipulation of plunger manipulation unit and is placed in a specific location within the barrel during centrifuge.
Abstract translation: 目的：提供一种注射器，以通过注射器的自身结构来限制柱塞在枪管周围的布置，而不需要单独的固定装置。 构成：注射器包括：在其一端形成有喷嘴的筒体（110）; 柱塞（120），其被容纳在所述筒体中以便在所述筒体内沿直线移动; 并且布置在筒体的另一端部的柱塞操作单元（130）与柱塞往复运动，并且选择性地限制柱塞围绕筒的布置。 柱塞与柱塞操作单元的往复运动操作相关联，并且在离心机期间放置在筒体内的特定位置。
-
公开(公告)号：KR101043228B1
公开(公告)日：2011-06-21
申请号：KR1020100099124
申请日：2010-10-12
Applicant: 서울대학교산학협력단
Abstract: PURPOSE: A syringe is provided to restrict the arrangement of a plunger about a barrel through the self-structure of the syringe. CONSTITUTION: A syringe comprises: a barrel(110) in which a nozzle is formed in one end thereof; and a plunger(120) which is received into the barrel in order to move in a straight line within the barrel. In the wall of the barrel, a guide slot(114) is penetrated. In the inner wall surface of the guide slot, a plurality of restricting grooves(140) are formed at an interval along the guide slot. A plunger handle(130) is integrally connected to the plunger and is located on the outside of the barrel. The plunger moves straight by the manipulation of the plunger handle. The plunger handle is selectively restricted in the restricting groove.
Abstract translation: 目的：提供注射器以通过注射器的自身结构来限制柱塞在筒周围的布置。 构成：注射器包括：在其一端形成有喷嘴的筒体（110）; 以及柱塞（120），所述柱塞（120）被容纳在所述筒体中以便在所述筒体内沿直线移动。 在桶的壁中，引导槽（114）被穿透。 在引导槽的内壁表面中，沿着引导槽以一定间隔形成多个限制槽（140）。 柱塞手柄（130）与柱塞一体连接并位于筒体的外侧。 柱塞通过操纵柱塞把手直线移动。 在限制槽中选择性地限制柱塞手柄。
-
公开(公告)号：KR101617881B1
公开(公告)日：2016-05-04
申请号：KR1020110020074
申请日：2011-03-07
Applicant: 서울대학교산학협력단
Abstract: 처리대상물을보다신속하고간단하게원심분리할수 있는원심분리방법및 원심분리용주사기가개시된다. 일단에노즐이형성된주사기를이용한원심분리방법은, 주사기내부에처리대상물을저장하는단계, 주사기내부의처리대상물을제1원심분리하는단계, 제1원심분리에의해노즐측에배치된일 특정성분을노즐을통해배출하는단계, 주사기를역전시켜주사기내부의처리대상물을제2원심분리하는단계, 및제2원심분리에의해노즐측에배치된다른특정성분을노즐을통해배출하는단계를포함한다.
-
公开(公告)号：KR1020160006635A
公开(公告)日：2016-01-19
申请号：KR1020150174881
申请日：2015-12-09
Applicant: 서울대학교산학협력단
Abstract: 원심분리에의해처리대상물로부터목적성분을추출하기위해사용되는원심분리용주사기에는, 일단에노즐이형성된배럴, 및배럴의타단에서배럴내부에직선이동가능하게수용되는플런저를포함하며, 플런저의플런저헤드에는목적성분의유착을저감시키기위한유착방지부가형성된다.
Abstract translation: 用于通过离心分离从物体中提取目标成分的用于离心分离的注射器包括在一端包括喷嘴的筒体; 以及存储在所述筒体内的能够从所述筒体的另一端线性移动的柱塞，其中，在所述柱塞的柱塞头上形成有用于减少所述目标部件的粘合的凝固防止部。 本发明提供了一种用于离心分离的注射器，从物体中快速且简单地提取特定的组分。
-
公开(公告)号：KR101043231B1
公开(公告)日：2011-06-21
申请号：KR1020100099126
申请日：2010-10-12
Applicant: 서울대학교산학협력단
Abstract: PURPOSE: A centrifugation and an adapter used for the same are provided to proceed centrifugation using existing syringe without design changes in existing syringe. CONSTITUTION: The adapter includes: adapter body(201); a barrel settling portion(210); and a plunger settling portion(220). The upper side of the adapter is opened and the adapter is fixed to centrifuge to be equipped and separated one way or the other direction altogether. The barrel settling portion is formed in the upper side of the adapter body. The barrel settling portion settles the barrel(110). The plunger settling portion is formed in the upper side of the adapter body. The plunger settling portion settles a plunger(120). The plunger settling portion includes a flange fixing groove(222). A plurality of the flange fixing groove is formed into the different location separated from the barrel settling portion. The flange fixing groove fixes both sides of the end flange(122).
Abstract translation: 目的：提供用于其的离心分离和适配器，以便使用现有的注射器进行离心，而不会在现有的注射器中进行设计改变。 配置：适配器包括：适配器主体（201）; 桶沉降部分（210）; 和柱塞沉降部分（220）。 打开适配器的上侧，并将适配器固定在离心机上，使之完全相互分离或分离。 筒体沉降部分形成在适配器主体的上侧。 桶沉降部分使桶（110）沉降。 柱塞沉降部分形成在适配器主体的上侧。 柱塞沉降部分沉降柱塞（120）。 柱塞沉降部分包括凸缘固定槽（222）。 多个凸缘固定槽形成为与筒沉降部分分离的不同位置。 凸缘固定槽固定端缘（122）的两侧。
-
-
-
-
-
-
-
-
-
Search Results
15
records
(took 0.022 seconds)
