-
公开(公告)号：JP2012228248A
公开(公告)日：2012-11-22
申请号：JP2012116896
申请日：2012-05-22
Applicant: Abbott Lab , アボット・ラボラトリーズAbbott Laboratories
Inventor： WU CHENGBIN , GHAYUR TARIQ , DIXON RICHARD W , SALFELD JOCHEN G
IPC: C12N15/09 , A61K39/395 , A61K45/00 , A61P1/04 , A61P1/16 , A61P1/18 , A61P3/06 , A61P3/08 , A61P3/10 , A61P3/14 , A61P5/14 , A61P5/18 , A61P7/00 , A61P7/04 , A61P7/06 , A61P9/04 , A61P9/06 , A61P9/08 , A61P9/10 , A61P9/12 , A61P11/00 , A61P11/02 , A61P11/06 , A61P13/12 , A61P15/08 , A61P17/00 , A61P17/02 , A61P17/06 , A61P17/14 , A61P19/02 , A61P19/10 , A61P21/00 , A61P21/04 , A61P25/00 , A61P25/06 , A61P25/14 , A61P25/16 , A61P25/18 , A61P25/24 , A61P25/28 , A61P25/32 , A61P27/02 , A61P29/00 , A61P31/00 , A61P31/04 , A61P31/10 , A61P31/12 , A61P31/18 , A61P33/00 , A61P33/02 , A61P33/06 , A61P33/08 , A61P35/00 , A61P35/02 , A61P37/06 , A61P37/08 , C07K16/24 , C07K16/28 , C07K16/46 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12P21/08
CPC classification number: Y02A50/386 , Y02A50/401 , Y02A50/41 , Y02A50/412 , Y02A50/478 , Y02A50/58
Abstract: PROBLEM TO BE SOLVED: To provide engineered multivalent and multispecific binding proteins, methods for making the proteins, and methods for using the proteins in the prevention and/or treatment of acute and chronic inflammatory and other diseases.SOLUTION: The binding protein comprises a polypeptide chain, wherein the polypeptide chain comprises VD1-(X1)-VD2-C-(X2), wherein VD1 is a first variable domain, VD2 is a second variable domain, C is a constant domain, X1 represents an amino acid or polypeptide, X2 represents an Fc region and n is 0 or 1.
Abstract translation: 要解决的问题：提供工程化的多价和多特异性结合蛋白，制备蛋白质的方法，以及使用蛋白质预防和/或治疗急性和慢性炎症和其他疾病的方法。 解决方案：结合蛋白包含多肽链，其中多肽链包含VD1-（X1）-VD2-C-（X2）
版权所有（C）2013，JPO＆INPIT -
公开(公告)号：WO2009149189A3
公开(公告)日：2010-03-04
申请号：PCT/US2009046137
申请日：2009-06-03
Applicant: ABBOTT LAB , GHAYUR TARIQ , ISAKSON PETER C , OLSON LISA M , WU CHENGBIN , HUGUNIN MARGARET , KAMATH RAJESH V , CUFF CAROLYN A , ALLEN HAMISH J
Inventor： GHAYUR TARIQ , ISAKSON PETER C , OLSON LISA M , WU CHENGBIN , HUGUNIN MARGARET , KAMATH RAJESH V , CUFF CAROLYN A , ALLEN HAMISH J
CPC classification number: C07K16/2887 , A61K39/3955 , A61K45/06 , A61K47/48546 , A61K47/6845 , A61K2039/505 , A61K2039/70 , C07K16/22 , C07K16/241 , C07K16/244 , C07K16/245 , C07K16/247 , C07K16/248 , C07K16/2866 , C07K16/468 , C07K2317/24 , C07K2317/31 , C07K2317/35 , C07K2317/64 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/92 , G01N33/6869 , G01N2333/545
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
Abstract translation: 本发明涉及工程化的多价和多特异性结合蛋白，制备方法，具体涉及用于预防，诊断和/或治疗疾病的用途。
-
公开(公告)号：WO2007024715A3
公开(公告)日：2008-10-30
申请号：PCT/US2006032398
申请日：2006-08-18
Applicant: ABBOTT LAB , WU CHENGBIN , GHAYUR TARIQ , DIXON RICHARD W , SALFELD JOCHEN G
Inventor： WU CHENGBIN , GHAYUR TARIQ , DIXON RICHARD W , SALFELD JOCHEN G
CPC classification number: C07K16/241 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K16/244 , C07K16/28 , C07K16/468 , C07K2317/21 , C07K2317/31 , C07K2317/64 , C07K2317/94
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention and/or treatment of acute and chronic inflammatory and other diseases.
Abstract translation: 本发明涉及工程化的多价和多特异性结合蛋白，制备方法，特别涉及它们在预防和/或治疗急性和慢性炎症和其他疾病中的用途。
-
公开(公告)号：WO2008024188A8
公开(公告)日：2008-07-03
申请号：PCT/US2007017340
申请日：2007-08-03
Applicant: ABBOTT LAB , WU CHENGBIN , GHAYUR TARIQ , DIXON RICHARD W , SALFELD JOCHEN G
Inventor： WU CHENGBIN , GHAYUR TARIQ , DIXON RICHARD W , SALFELD JOCHEN G
CPC classification number: C07K16/468 , A61K39/3955 , A61K45/06 , A61K47/42 , A61K47/48384 , A61K47/6803 , A61K51/1093 , A61K2039/505 , C07K16/22 , C07K16/24 , C07K16/241 , C07K16/244 , C07K16/245 , C07K16/2809 , C07K16/2887 , C07K16/2896 , C07K16/40 , C07K16/46 , C07K16/467 , C07K2317/24 , C07K2317/31 , C07K2317/51 , C07K2317/522 , C07K2317/56 , C07K2317/64 , C07K2317/76
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention and/or treatment of acute and chronic inflammatory and other diseases.
Abstract translation: 本发明涉及工程化的多价和多特异性结合蛋白，制备方法，特别涉及它们在预防和/或治疗急性和慢性炎症和其他疾病中的用途。
-
5.发明申请
公开(公告)号：WO2012088290A2
公开(公告)日：2012-06-28
申请号：PCT/US2011066530
申请日：2011-12-21
Applicant: ABBOTT LAB , WU CHENGBIN , YING HUA , GHAYUR TARIQ , GOODREAU CARRIE , BARDWELL PHILIP
Inventor： WU CHENGBIN , YING HUA , GHAYUR TARIQ , GOODREAU CARRIE , BARDWELL PHILIP
IPC: A61K39/395 , A61P37/04 , C07K16/24 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/13 , C12N15/63 , C12P21/00 , G01N33/53
CPC classification number: C07K16/468 , A61K2039/505 , C07K16/241 , C07K16/244 , C07K16/26 , C07K16/2809 , C07K16/2863 , C07K16/2887 , C07K16/32 , C07K2317/31 , C07K2317/35 , C07K2317/56 , C07K2317/64 , C07K2317/73 , C07K2317/76 , C07K2317/92 , G01N2333/525 , G01N2333/54 , G01N2405/00
Abstract: The present invention provides engineered multivalent and multispecific binding proteins, as well as methods of making them. Methods for using the multivalent and multispecific binding proteins of the invention in the prevention, diagnosis, and/or treatment of disease are also provided.
Abstract translation: 本发明提供工程化的多价和多特异性结合蛋白，以及制备它们的方法。 还提供了在预防，诊断和/或治疗疾病中使用本发明的多价和多特异性结合蛋白的方法。
-
Patent Agency Ranking
公开(公告)号：WO2007024715A2
公开(公告)日：2007-03-01
申请号：PCT/US2006032398
申请日：2006-08-18
Applicant: ABBOTT LAB , WU CHENGBIN , GHAYUR TARIQ , DIXON RICHARD W , SALFELD JOCHEN G
Inventor： WU CHENGBIN , GHAYUR TARIQ , DIXON RICHARD W , SALFELD JOCHEN G
IPC: A61K49/00 , A61K31/192 , A61K31/343 , A61K31/365 , A61K31/4152 , A61K31/445 , A61K31/496 , A61K31/551 , A61K31/60 , A61K39/395
CPC classification number: C07K16/241 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K16/244 , C07K16/28 , C07K16/468 , C07K2317/21 , C07K2317/31 , C07K2317/64 , C07K2317/94
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention and/or treatment of acute and chronic inflammatory and other diseases.
Abstract translation: 本发明涉及工程化的多价和多特异性结合蛋白，制备方法，特别涉及其用于预防和/或治疗急性和慢性炎症和其它疾病的用途。
-
7.发明申请IL-1 -ALPHA AND -BETA BISPECIFIC DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND THEIR USE 审中-公开IL-1 -ALPHA和-BETA双重可变域免疫球蛋白及其用途
公开(公告)号：WO2012121775A3
公开(公告)日：2012-11-01
申请号：PCT/US2011066130
申请日：2011-12-20
Applicant: ABBOTT LAB , WU CHENGBIN
Inventor： WU CHENGBIN
IPC: C07K16/24
CPC classification number: A61K39/395 , A61K2039/505 , A61K2039/507 , C07K16/245 , C07K16/468 , C07K2317/31 , C07K2317/35 , C07K2317/64 , C07K2317/76 , C07K2317/92 , C07K2319/00
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
Abstract translation: 本发明涉及工程化的多价和多特异性结合蛋白，制备方法，具体涉及用于预防，诊断和/或治疗疾病的用途。
-
公开(公告)号：WO2008024188A3
公开(公告)日：2008-09-04
申请号：PCT/US2007017340
申请日：2007-08-03
Applicant: ABBOTT LAB , WU CHENGBIN , GHAYUR TARIQ , DIXON RICHARD W , SALFELD JOCHEN G
Inventor： WU CHENGBIN , GHAYUR TARIQ , DIXON RICHARD W , SALFELD JOCHEN G
IPC: A61K39/00
CPC classification number: C07K16/468 , A61K39/3955 , A61K45/06 , A61K47/42 , A61K47/48384 , A61K47/6803 , A61K51/1093 , A61K2039/505 , C07K16/22 , C07K16/24 , C07K16/241 , C07K16/244 , C07K16/245 , C07K16/2809 , C07K16/2887 , C07K16/2896 , C07K16/40 , C07K16/46 , C07K16/467 , C07K2317/24 , C07K2317/31 , C07K2317/51 , C07K2317/522 , C07K2317/56 , C07K2317/64 , C07K2317/76
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention and/or treatment of acute and chronic inflammatory and other diseases.
Abstract translation: 本发明涉及工程化的多价和多特异性结合蛋白，制备方法，特别涉及其用于预防和/或治疗急性和慢性炎症和其它疾病的用途。
-
9.发明公开
公开(公告)号：EP1928506A4
公开(公告)日：2009-10-21
申请号：EP06813554
申请日：2006-08-18
Applicant: ABBOTT LAB
Inventor： WU CHENGBIN , GHAYUR TARIQ , DIXON RICHARD W , SALFELD JOCHEN G
CPC classification number: C07K16/241 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K16/244 , C07K16/28 , C07K16/468 , C07K2317/21 , C07K2317/31 , C07K2317/64 , C07K2317/94
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention and/or treatment of acute and chronic inflammatory and other diseases.
Abstract translation: 本发明涉及工程化的多价和多特异性结合蛋白，制备方法，特别涉及其用于预防和/或治疗急性和慢性炎症和其它疾病的用途。
-
公开(公告)号：WO2012121775A2
公开(公告)日：2012-09-13
申请号：PCT/US2011066130
申请日：2011-12-20
Applicant: ABBOTT LAB , WU CHENGBIN
Inventor： WU CHENGBIN
IPC: C07K16/24
CPC classification number: A61K39/395 , A61K2039/505 , A61K2039/507 , C07K16/245 , C07K16/468 , C07K2317/31 , C07K2317/35 , C07K2317/64 , C07K2317/76 , C07K2317/92 , C07K2319/00
Abstract: The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
-
-
-
-
-
-
-
-
-
Search Results
74
records
(took 0.029 seconds)
