CHROMATOGRAPHY COLUMN USING GRADUALLY VARIED FILTER MATERIAL FOR REDUCING INCREASE IN BACK PRESSURE

    公开(公告)号:JP2000065813A

    公开(公告)日:2000-03-03

    申请号:JP23462999

    申请日:1999-08-20

    Inventor: DEWAELE CHRIS

    Abstract: PROBLEM TO BE SOLVED: To prevent increase in a back pressure of a column because of fragments of solid accompanying a carrier fluid by constructing a filter material into a multilayer structure of non-woven sintered stainless steel fiber and gradually increasing density of the fiber along the flow direction in charging of the fiber. SOLUTION: A cartridge made of metal such as stainless steel is constructed into a hollow cylindrical tube 11. In the upstream end and the downstream end of a chamber 21 for a separator, screens 23, 24 made of sintered non-woven stainless steel fiber filter material discs are arranged, and in the screens 23, 24, the side provided with a larger pore size is oriented on the flow direction upstream side. As the screens 23, 24 are thin and flexible, they are supported by means of porous sintered stainless steel discs 25, 26. A difference in the pore size of the filters is about 1-50 μm and is abut 2-20 μm desirably. As the gradually variable filter material, a filter varied in about 3-6 steps is preferable.

    4.
    发明专利
    未知

    公开(公告)号:DE69939043D1

    公开(公告)日:2008-08-21

    申请号:DE69939043

    申请日:1999-08-18

    Inventor: DEWAELE CHRIS

    Abstract: Cartridges (11) for high performance liquid chromatography are designed for use with a large number of repeated injections without excessive buildup of back pressure by the inclusion of a filter medium (23,24) consisting of sintered stainless steel fibers formed into a nonwoven structure whose pore size decreases in the direction of flow down to a pore size of less than ten microns.

    GRADED EXTERNAL PREFILTER ELEMENT FOR CONTINUOUS-FLOW SYSTEMS

    公开(公告)号:CA2658777A1

    公开(公告)日:2008-01-31

    申请号:CA2658777

    申请日:2007-07-24

    Abstract: A prefilter element for continuous flow systems as illustrated by a high- performance liquid chromatography cartridge or column is constructed with a gradient filter that has a gradient in average pore size over its thickness, the pore size decreasing in the direction of flow. This prefilter element i s retained in a housing separate from any functional components of the conti nuous-flow system other than the prefilter element itself, the prefilter ele ment being separable from the other functional components to allow the prefi lter to be replaced without disturbing any other functional components.

    GRADED EXTERNAL PREFILTER ELEMENT FOR CONTINUOUS-FLOW SYSTEMS
    7.
    发明申请
    GRADED EXTERNAL PREFILTER ELEMENT FOR CONTINUOUS-FLOW SYSTEMS 审中-公开
    用于连续流动系统的分级外部先导元件

    公开(公告)号:WO2008014237A3

    公开(公告)日:2008-08-07

    申请号:PCT/US2007074182

    申请日:2007-07-24

    CPC classification number: G01N30/603 B01D15/12 G01N30/6091

    Abstract: A prefilter element for continuous flow systems as illustrated by a high-performance liquid chromatography cartridge or column is constructed with a gradient filter that has a gradient in average pore size over its thickness, the pore size decreasing in the direction of flow. This prefilter element is retained in a housing separate from any functional components of the continuous-flow system other than the prefilter element itself, the prefilter element being separable from the other functional components to allow the prefilter to be replaced without disturbing any other functional components.

    Abstract translation: 如高性能液相色谱柱或柱所示的用于连续流动系统的预过滤器元件由在其厚度上具有平均孔径梯度的梯度过滤器构成,孔径在流动方向上减小。 该预滤器元件被保持在与预滤器元件本身不同的任何功能部件的外壳中,预滤器元件可与其他功能部件分离,以允许预滤器被替换而不干扰任何其他功能部件。

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