公开(公告)号：AU2024278436A1

公开(公告)日：2025-01-30

申请号：AU2024278436

申请日：2024-12-16

Applicant: BIO RAD EUROPE GMBH ,  BIO RAD LABORATORIES INC

Inventor： HANDIQUE KALYAN ,  LEBOFSKY RONALD ,  MACKE EMILIE CELINE CLAUDIE ,  DIEVART REBECCA ,  QUIRING CHRISTOPHE ,  PIERRE SOPHIE

IPC: C12M1/34 ,  B01L3/00 ,  C12M1/18 ,  C12M3/00 ,  G01N33/48 ,  G01N37/00

Abstract: Abstract A system for target detection, the system including: a base substrate; a set of sample processing regions defined at a broad surface of the substrate, wherein each of the set of sample processing regions includes: a set of microwell subarrays arranged in a gradient between an upstream end and a downstream end of each respective sample processing region, and a boundary separating each respective sample processing region from adjacent sample processing regions; and a cover substrate configured to mate with the base substrate in a coupled mode, the cover substrate comprising a network of venting channels aligned with the set of sample processing regions upon mating the base substrate with the cover substrate in the coupled mode, the network of venting channels providing gas exchange between the base substrate and an environment surrounding the microwell assembly. Sample Processing Initial Region Base 120 Substrate Subarray 110 --- 90 Terminal Boundary Subarray 190 Microwell Initial Assembly Subarray 100 Subsrate Terminal Subarray CROSS-SECTIONAL VIEW

公开(公告)号：EP3161157A4

公开(公告)日：2017-12-20

申请号：EP15790435

申请日：2015-06-24

Applicant: BIO-RAD LABORATORIES INC

Inventor： AGRESTI JEREMY ,  COOPER SAMANTHA ,  KARLIN-NEUMANN GEORGE ,  HEREDIA NICK ,  LEBOFSKY RONALD

IPC: C12Q1/68 ,  C12N15/10

CPC classification number: C12N15/1065 ,  C12Q1/6806 ,  C12Q1/6853 ,  C12Q2521/531 ,  C12Q2525/161 ,  C12Q2525/204 ,  C12Q2535/122 ,  C12Q2565/629 ,  C12Q2563/149 ,  C12Q2563/159 ,  C12Q2563/179 ,  C12Q2565/514

Abstract: Methods, compositions, and kits are provided for nucleic acid analysis, including single cell analysis.