公开(公告)号：WO2012078337A2

公开(公告)日：2012-06-14

申请号：PCT/US2011/061305

申请日：2011-11-18

Applicant: COLGATE-PALMOLIVE COMPANY ,  CHOPRA, Suman ,  PATEL, Rahul ,  ZAIDEL, Lynette Anne

Inventor： CHOPRA, Suman ,  PATEL, Rahul ,  ZAIDEL, Lynette Anne

IPC: A61Q11/00

CPC classification number: A61Q11/00 ,  A61K8/0241 ,  A61K8/25 ,  A61K8/44 ,  A61K2800/412

Abstract: An oral care composition includes an effective amount of a basic amino acid in free or salt form; and an effective amount of calcium silicate particles. The calcium silicate particles have an average diameter of less than about 5 microns, such that they can occlude dentinal tubules of the teeth. An oral care method includes applying the composition to an oral cavity of a subject to reduce or inhibit hypersensitivity of the teeth and to achieve other benefits.

Abstract translation: 口腔护理组合物包含有效量的游离或盐形式的碱性氨基酸; 和有效量的硅酸钙颗粒。 硅酸钙颗粒的平均直径小于约5微米，使得它们可以堵塞牙齿的牙质小管。 口腔护理方法包括将组合物施用于受试者的口腔以减少或抑制牙齿的超敏反应并实现其它益处。

公开(公告)号：WO2013105924A2

公开(公告)日：2013-07-18

申请号：PCT/US2011/066496

申请日：2011-12-21

Applicant: COLGATE-PALMOLIVE COMPANY ,  MALONEY, Venda Porter ,  CHOPRA, Suman ,  LEITE, Sergio ,  PAN, Long ,  PATEL, Rahul

Inventor： MALONEY, Venda Porter ,  CHOPRA, Suman ,  LEITE, Sergio ,  PAN, Long ,  PATEL, Rahul

IPC: A61K31/28

CPC classification number: A61K8/28 ,  A61K8/345 ,  A61K8/37 ,  A61K8/375 ,  A61K8/44 ,  A61K8/492 ,  A61K2800/31 ,  A61K2800/58 ,  A61Q11/00

Abstract: Described herein are compositions comprising zirconium amino acid complexes suspended in a hydrophobic carrier; and methods of making and using the same.

Abstract translation: 本文描述了包含悬浮于疏水性载体中的锆氨基酸络合物的组合物; 以及制作和使用它们的方法。

公开(公告)号：WO2016014012A1

公开(公告)日：2016-01-28

申请号：PCT/US2014/047355

申请日：2014-07-21

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： MALONEY, Venda ,  CHOPRA, Suman ,  PATEL, Rahul

IPC: A61K8/24 ,  A61K8/25 ,  A61Q11/00 ,  A61K8/02

CPC classification number: A61K8/24 ,  A61K8/0241 ,  A61K8/21 ,  A61K8/25 ,  A61K8/345 ,  A61K8/442 ,  A61K8/463 ,  A61K8/49 ,  A61K8/73 ,  A61K8/731 ,  A61K8/86 ,  A61K2800/28 ,  A61K2800/412 ,  A61K2800/48 ,  A61K2800/92 ,  A61Q11/00

Abstract: The present invention provides an oral care composition comprising from 3 to 12 weight% calcium pyrophosphate and from 10 to 19 weight% precipitated silica, based on the total weight of the composition, wherein the precipitated silica has a pellicle cleaning ratio of greater than 85. The present invention further provides a method of cleaning and/or polishing and/or whitening an oral surface comprising contacting the oral surface with the oral care composition.

Abstract translation: 本发明提供一种包含3-12重量％焦磷酸钙和10-19重量％沉淀二氧化硅的口腔护理组合物，基于组合物的总重量，其中沉淀二氧化硅具有大于85的防护薄膜清洁率。 本发明还提供了一种清洁和/或抛光和/或增白口腔表面的方法，包括使口腔表面与口腔护理组合物接触。

公开(公告)号：WO2012087281A1

公开(公告)日：2012-06-28

申请号：PCT/US2010/061324

申请日：2010-12-20

Applicant: COLGATE-PALMOLIVE COMPANY ,  BOYD, Thomas James ,  CHOPRA, Suman Kumar ,  MELLO, Sarita Vera ,  PATEL, Rahul ,  ONTUMI, Dennis Kembero

Inventor： BOYD, Thomas James ,  CHOPRA, Suman Kumar ,  MELLO, Sarita Vera ,  PATEL, Rahul ,  ONTUMI, Dennis Kembero

IPC: A61K8/11 ,  A61K8/24 ,  A61K8/44 ,  A61K8/65 ,  A61K8/81 ,  A61K8/92 ,  A61Q11/00

CPC classification number: A61K8/8164 ,  A61K8/11 ,  A61K8/24 ,  A61K8/44 ,  A61K8/65 ,  A61K8/922 ,  A61K2800/31 ,  A61Q11/00

Abstract: A oral care composition includes: (a) a hydrophilic film-forming polymer; and (b) a hydrophobic carrier, wherein the hydrophilic film-forming polymer is a film-forming polymer effective to occlude dentinal tubules and the oral care composition contains 0-10 wt.% water. The hydrophilic film-forming polymer is preferably GANTREZ S. The hydrophobic carrier is preferably a vegetable oil. A method of cleaning teeth includes applying to the teeth the oral care composition such that the hydrophilic film-forming polymer occludes dentinal tubules. A toothbrush includes: a handle; a head mounted to the handle, the head comprising an outer surface and a plurality of tooth cleaning elements extending outwardly from the outer surface; and a gelatin capsule containing the oral care composition positioned on the head.

Abstract translation: 口腔护理组合物包括：（a）亲水成膜聚合物; 和（b）疏水性载体，其中亲水性成膜聚合物是有效闭塞牙质小管的成膜聚合物，口腔护理组合物含有0-10重量％的水。 亲水性成膜聚合物优选为GANTREZ S.疏水载体优选为植物油。 清洁牙齿的方法包括将口腔护理组合物施用于牙齿，使得亲水成膜聚合物封闭牙质小管。 牙刷包括：手柄; 头部，其安装到手柄上，头部包括外表面和从外表面向外延伸的多个牙齿清洁元件; 和含有定位在头部上的口腔护理组合物的明胶胶囊。

公开(公告)号：WO2015099638A1

公开(公告)日：2015-07-02

申请号：PCT/US2013/077373

申请日：2013-12-23

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： MALONEY, Venda P. ,  CHOPRA, Suman K. ,  PATEL, Rahul

IPC: A61K8/49 ,  A61Q11/00 ,  A61K8/73 ,  A61K8/02

CPC classification number: A61K8/731 ,  A61K8/0216 ,  A61K8/0254 ,  A61K8/25 ,  A61K8/345 ,  A61K8/463 ,  A61K8/492 ,  A61K8/58 ,  A61K8/60 ,  A61K8/8111 ,  A61K8/8141 ,  A61K8/8164 ,  A61K2800/30 ,  A61K2800/41 ,  A61K2800/43 ,  A61K2800/48 ,  A61K2800/5424 ,  A61K2800/5922 ,  A61K2800/594 ,  A61K2800/596 ,  A61Q11/00

Abstract: A tooth whitening composition containing film flakes of a hydroxyalkyl methyl cellulose and a pigment in combination with an orally acceptable carrier vehicle.

Abstract translation: 一种牙齿美白组合物，其含有羟烷基甲基纤维素的薄膜片和与口腔可接受的载体载体组合的颜料。

公开(公告)号：WO2012078136A1

公开(公告)日：2012-06-14

申请号：PCT/US2010/059182

申请日：2010-12-07

Applicant: COLGATE-PALMOLIVE COMPANY ,  CHOPRA, Suman Kumar ,  PATEL, Rahul

Inventor： CHOPRA, Suman Kumar ,  PATEL, Rahul

IPC: A61K8/04 ,  A61K8/25 ,  A61Q11/00 ,  C01B33/24

CPC classification number: A61K8/25 ,  A61K8/044 ,  A61K2800/412 ,  A61Q11/00 ,  C01B33/24 ,  C01P2004/61 ,  C01P2004/62 ,  C01P2006/12

Abstract: An oral care composition includes an effective amount of calcium silicate particles. The calcium silicate particles have an average diameter of less than about 5 microns, such that they can occlude dentinal tubules of the teeth. An oral care method includes applying the composition to an oral cavity of a subject to reduce or inhibit hypersensitivity of the teeth and to achieve other benefits.

Abstract translation: 口腔护理组合物包含有效量的硅酸钙颗粒。 硅酸钙颗粒的平均直径小于约5微米，使得它们可以堵塞牙齿的牙质小管。 口腔护理方法包括将组合物施用于受试者的口腔以减少或抑制牙齿的超敏反应并实现其它益处。

公开(公告)号：WO2017196299A1

公开(公告)日：2017-11-16

申请号：PCT/US2016/031608

申请日：2016-05-10

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： PAN, Long ,  SEO, Jung ,  NABI, Zeenat ,  CHENG, Shujiang ,  SOLIMAN, Nadia ,  DU-THUMM, Laurence ,  SCALA, Diana ,  HOLERCA, Nick ,  ROBBINS, Kyle ,  PATEL, Rahul

IPC: A61K8/46 ,  A61Q15/00 ,  A61K8/97

Abstract: Personal care compositions containing active ingredients and an anti-irritant combination of aloe and taurine are disclosed. Methods of preparing the personal care composition and uses of the personal care composition are also disclosed.

Abstract translation: 公开了含有活性成分和芦荟和牛磺酸的抗刺激剂组合的个人护理组合物。 还公开了制备个人护理组合物的方法和个人护理组合物的用途。

公开(公告)号：WO2013095435A1

公开(公告)日：2013-06-27

申请号：PCT/US2011/066485

申请日：2011-12-21

Applicant: COLGATE-PALMOLIVE COMPANY ,  CHOPRA, Suman ,  FEI, Lin ,  PATEL, Rahul

Inventor： CHOPRA, Suman ,  FEI, Lin ,  PATEL, Rahul

IPC: A61K8/25 ,  A61K8/81 ,  A61Q11/00

CPC classification number: A61K8/25 ,  A61K8/8164 ,  A61Q11/00

Abstract: Described herein are oral care compositions comprising (i) a magnesium alkali metal silicate complex clay, and (ii) an orally acceptable anionic polymer, in a dentifrice base, which compositions are useful for alleviating dental sensitivity. Also provided for, are methods of making and using the compositions described herein.

Abstract translation: 本文描述了口腔护理组合物，其包含（i）镁碱金属硅酸盐复合粘土和（ii）口腔可接受的阴离子聚合物，其在洁齿剂基质中，该组合物可用于减轻牙齿敏感性。 还提供了制备和使用本文所述组合物的方法。

公开(公告)号：WO2012087279A1

公开(公告)日：2012-06-28

申请号：PCT/US2010/061305

申请日：2010-12-20

Applicant: COLGATE-PALMOLIVE COMPANY ,  ONTUMI, Dennis, Kembero ,  MELLO, Sarita, Vera ,  CHOPRA, Suman, Kumar ,  BROWN, James, Richard ,  BOYD, Thomas, James ,  PATEL, Rahul

Inventor： ONTUMI, Dennis, Kembero ,  MELLO, Sarita, Vera ,  CHOPRA, Suman, Kumar ,  BROWN, James, Richard ,  BOYD, Thomas, James ,  PATEL, Rahul

IPC: A61K8/11 ,  A61K8/31 ,  A61K8/44 ,  A61K8/65 ,  A61K8/81 ,  A61K8/92 ,  A61Q11/00

CPC classification number: A61K8/11 ,  A46B11/001 ,  A61K8/31 ,  A61K8/44 ,  A61K8/65 ,  A61K8/8111 ,  A61K8/8164 ,  A61K8/922 ,  A61K2800/31 ,  A61Q11/00

Abstract: A oral care composition includes: (a) a guanidine active; (b) a film-forming polymer; (c) a hydrophobic viscosity modifier in an amount sufficient to provide the oral care composition with a particle settling time greater than 20 minutes; and (d) an oil carrier. The guanidine active is preferably L-arginine. The film-forming polymer is preferably GANTREZ. The hydrophobic viscosity modifier is preferably a gelled mineral oil. The oil carrier is preferably a vegetable oil. A method of cleaning teeth includes applying to the teeth the oral care composition such that the oral care composition cleans the teeth. A oral care implement includes: a handle; a head mounted to the handle, the head having an outer surface and a plurality of tooth cleaning elements extending outwardly from the outer surface; and a gelatin capsule containing the oral care composition positioned on the head.

Abstract translation: 口腔护理组合物包括：（a）活性的胍; （b）成膜聚合物; （c）疏水性粘度调节剂，其量足以使口腔护理组合物的沉降时间大于20分钟; 和（d）油载体。 胍活性剂优选为L-精氨酸。 成膜聚合物优选为GANTREZ。 疏水性粘度调节剂优选为凝胶状矿物油。 油载体优选为植物油。 清洁牙齿的方法包括将口腔护理组合物施用于牙齿，使得口腔护理组合物清洁牙齿。 口腔护理器具包括：手柄; 头部，其安装到手柄上，头部具有外表面和从外表面向外延伸的多个牙齿清洁元件; 和含有定位在头部上的口腔护理组合物的明胶胶囊。

公开(公告)号：EP3086768B1

公开(公告)日：2019-02-20

申请号：EP13821363.2

申请日：2013-12-23

Applicant: Colgate-Palmolive Company

Inventor： MALONEY, Venda Porter ,  CHOPRA, Suman K. ,  PATEL, Rahul

IPC: A61K8/25 ,  A61K8/73