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公开(公告)号：US20190352682A1
公开(公告)日：2019-11-21
申请号：US16372083
申请日：2019-04-01
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor： Alexander Brett Foster , Jonathan Kennedy , Paul S. Pearlman
Abstract: This disclosure relates to strategies for in vivo production of certain carbon-based products, for example, aminated aliphatic compounds having a carbon chain length of C5-C19.
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公开(公告)号：US10889839B2
公开(公告)日：2021-01-12
申请号：US16685290
申请日：2019-11-15
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor： Alexander Steinbüchel , Jessica Eggers , Alexander Brett Foster , Jonathan Kennedy
Abstract: Nonnaturally occurring organisms exhibiting improved carbon utilization and methods for production and use of these nonnaturally occurring organisms in chemical production from carbon containing feedstocks are provided.
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公开(公告)号：US20190233857A1
公开(公告)日：2019-08-01
申请号：US16264774
申请日：2019-02-01
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor： Daniel Bawdon , Mariusz Stanislaw Kamionka , Alexander Brett Foster , Arghya Barman
CPC classification number: C12P13/06 , C12N9/0006 , C12N9/1096 , C12N9/16 , C12N15/74 , C12Y101/01095 , C12Y206/01052 , C12Y301/03003
Abstract: Biosynthetic methods and materials for the production of compounds involved in serine metabolism, derivatives thereof and/or compounds related thereto are provided. Also provided are products produced in accordance with these methods and materials.
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公开(公告)号：US20190233849A1
公开(公告)日：2019-08-01
申请号：US16264739
申请日：2019-02-01
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor： Jonathan Paul Combe , Alexander Brett Foster , Arghya Barman
CPC classification number: C12P7/42 , C12N9/1029 , C12R1/01 , C12Y203/01009
Abstract: Methods and materials for the production of hydroxy fatty acid anions, including 2-hydroxyisobutyric acid (2-HIBA), and/or derivatives thereof and compounds related thereto are provided. Also provided are products produced in accordance with these methods and materials.
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公开(公告)号：US20190002927A1
公开(公告)日：2019-01-03
申请号：US16023055
申请日：2018-06-29
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor： Alexander Brett Foster , Leonard Keith Pattenden , Jonathan David Rand , Ana Teresa dos Santos Brito Mendes Roberts , Andrew Shaw , Mark Paul Taylor
Abstract: Systems, networks, methods, compositions and recombinant hosts for biosynthesizing hydrocarbons from a feedstock, such as gas, are provided.
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Patent Agency Ranking
公开(公告)号：US20190338376A1
公开(公告)日：2019-11-07
申请号：US16398384
申请日：2019-04-30
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor： Alexander Brett Foster , Jonathan Kennedy
Abstract: Methods for increasing carbon-based chemical product yield in an organism by genetically modifying one or more genes involved in a stringent response and/or in a regulatory network, nonnaturally occurring organisms having increased carbon-based chemical product yield, and methods for use in production of carbon-based chemical products are provided.
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7.发明申请公开(公告)号：US20180094282A1
公开(公告)日：2018-04-05
申请号：US15717065
申请日：2017-09-27
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor： Stephen Thomas Cartman , Alexander Brett Foster , Ana Teresa dos Santos Brito Mendes , Mark Paul Taylor
Abstract: Methods and compositions for synthesizing dienes and derivative thereof, such as isoprene, in Cupriavidus necator are provided.
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公开(公告)号：US10801046B2
公开(公告)日：2020-10-13
申请号：US15659505
申请日：2017-07-25
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor： Alexander Brett Foster , Stephen Thomas Cartman , Jonathan Kennedy , William Joseph Simmons
IPC: C12P7/62 , C12P7/42 , C12N15/09 , C12P7/64 , C12N15/52 , C12P13/00 , C12P7/24 , C12P7/40 , C07C47/12 , C07C47/19 , C07C55/16 , C07C59/147 , C07C223/02 , C07C225/06 , C07C229/08 , C12N9/04 , C12N9/10 , C12N9/16 , C12N9/88 , C12P7/18 , C12P7/44
Abstract: This document describes biochemical pathways for producing a difunctional product having an odd number of carbon atoms in vitro or in a recombinant host, or salts or derivatives thereof, by forming two terminal functional groups selected from carboxyl, amine, formyl, and hydroxyl groups in an aliphatic carbon chain backbone having an odd number of carbon atoms synthesized from (i) acetyl-CoA and propanedioyl-CoA via one or more cycles of methyl ester shielded carbon chain elongation or (ii) propanedioyl-[acp] via one or more cycles of methyl ester shielded carbon chain elongation. The biochemical pathways and metabolic engineering and cultivation strategies described herein rely on enzymes or homologs accepting methyl ester shielded aliphatic carbon chain backbones and maintaining the methyl ester shield for at least one further enzymatic step following one or more cycles of methyl ester shielded carbon chain elongation.
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9.发明授权公开(公告)号：US10538788B2
公开(公告)日：2020-01-21
申请号：US15717065
申请日：2017-09-27
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor： Stephen Thomas Cartman , Alexander Brett Foster , Ana Teresa dos Santos Brito Mendes Roberts , Mark Paul Taylor
Abstract: Methods and compositions for synthesizing dienes and derivative thereof, such as isoprene, in Cupriavidus necator are provided.
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公开(公告)号：US20190338375A1
公开(公告)日：2019-11-07
申请号：US16398351
申请日：2019-04-30
Applicant: INVISTA NORTH AMERICA S.A.R.L.
Inventor： Alexander Brett Foster , Jonathan Paul Combe , Arghya Barman
Abstract: Methods for increasing carbon-based chemical product yield in an organism by perturbing redox balance in an organism as well as nonnaturally occurring organisms with perturbed redox balance and methods for their use in producing carbon-based chemical products are provided.
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