Abstract:
This application describes methods, including non-naturally occurring methods, for biosynthesizing 3-hydroxy-3-methylglutaryl-coA and intermediates thereof, as well as non-naturally occurring hosts for producing 3-hydroxy-3-methylglutaryl-coA. This application also describes methods, including non-naturally occurring methods, for biosynthesizing isoprene and intermediates thereof, as well as non-naturally occurring hosts for producing isoprene.
Abstract:
Biocatalytic processes for producing a product wherein an aqueous stream comprising at least one fermentable substrate and/or a gaseous stream comprising at least one of CO 2 /H 2 , H 2 , methane, and/or CO are povided to a fermentation zone comprising at least one organism capable of metabolizing a substance present in one of the streams. The fermentation may operate at conditions to mixotrophically metabolize at least one gaseous substrate and at least one substrate present in the aqueous stream.
Abstract:
Biocatalytic processes for producing a product wherein an aqueous stream comprising at least one fermentable substrate and/or a gaseous stream comprising at least one of CO 2 /H 2 , H 2 , methane, and/or CO are povided to a fermentation zone comprising at least one organism capable of metabolizing a substance present in one of the streams. The fermentation may operate at conditions to mixotrophically metabolize at least one gaseous substrate and at least one substrate present in the aqueous stream.
Abstract translation:用于生产产物的生物催化方法,其中包含至少一种可发酵底物的含水物流和/或包含CO 2 / H 2中的至少一种的气态物流 甲烷和/或CO被提供给包含至少一种能够代谢存在于其中一种物质中的物质的生物体的发酵区。 发酵可以在混合营养代谢至少一种气态底物和存在于含水流中的至少一种底物的条件下进行。 p>
Abstract:
The present disclosure describes biocatalytic processes for producing a product, comprising providing an aqueous stream (AS) comprising at least one fermentable substrate and a gaseous stream (GS) comprising at least one of CO 2 /H 2 , H 2 , methane, and/or CO to a fermentation zone, wherein the GS and AS stream are optionally contacted and/or mixed; the fermentation zone comprising at least one organism capable of metabolizing an AS substrate and a GS substrate, wherein the fermentation operates at conditions to mixotrophically metabolize at least one gaseous substrate in the GS and at least one substrate in the AS, producing the product. The present disclosure also describes compositions comprising an AS, a GS, and an organism, wherein the organism or an equivalent or engineered equivalent thereof is a methanotroph or a hydrogen-metabolizing or CO-metabolizing chemolithotrophic organism, and wherein the organism is capable of mixotrophic metabolism of at least one gaseous substrate in the GS and at least one substrate in the AS. The present disclosure also describes a process wherein said fermentation operates at conditions to mixotrophically metabolize at least H 2 in the gaseous stream and glycerol and lactic acid in the aqueous stream. The present disclosure also describes a system for producing a fermentation or bio-derived product.
Abstract:
Embodiments of the present invention relate to methods for the biosynthesis of di- or trifunctional C7 alkanes in the presence of isolated enzymes or in the presence of a recombinant host cell expressing those enzymes. The di- or trifunctional C7 alkanes are useful as intermediates in the production of nylon-7, nylon-7,x, nylon-x,7, and polyesters.