公开(公告)号：WO2015195682A1

公开(公告)日：2015-12-23

申请号：PCT/US2015/036057

申请日：2015-06-16

Applicant: INVISTA TECHNOLOGIES S.À.R.L.

Inventor： BOTES, Adriana Leonora ,  CONRADIE, Alex Van Eck ,  HADDOUCHE, Ramdane

IPC: C12P7/42 ,  C12P7/44

CPC classification number: C12P13/001 ,  C07C47/02 ,  C07C47/12 ,  C07C59/01 ,  C07C59/325 ,  C07C223/02 ,  C08G63/06 ,  C12N9/0008 ,  C12N9/0077 ,  C12N9/1007 ,  C12N9/1096 ,  C12P7/24 ,  C12P7/40 ,  C12P7/42 ,  C12P7/44 ,  C12P7/62 ,  C12P7/6409 ,  C12P7/6436 ,  C12Y102/99006 ,  C12Y114/15001 ,  C12Y114/15003 ,  C12Y206/01018 ,  C12Y206/01019 ,  C12Y206/01029 ,  C12Y206/01048 ,  C12Y206/01082

Abstract: This document describes biochemical pathways for producing 6- hydroxyhexanoate methyl ester and hexanoic acid hexyl ester using one or more of a fatty acid O-methyltransferase, an alcohol O-acetyltransferase and a monooxygenase , as well as recombinant hosts expressing one or more of such enzymes. 6-hydroxyhexanoate methyl esters and hexanoic acid hexyl ester can be enzymatically converted to adipic acid, adipate semialdehyde, 6-aminohexanoate, 6-hydroxyhexanoate, hexamethylenediamine, and 1,6-hexanediol.

Abstract translation: 该文献描述了使用一种或多种脂肪酸O-甲基转移酶，醇O-乙酰转移酶和单加氧酶产生6-羟基己酸甲酯和己酸己酯的生化途径，以及表达一种或多种这样的酶的重组宿主 。 6-羟基己酸甲酯和己酸己酯可以酶促转化为己二酸，己二酸半醛，6-氨基己酸，6-羟基己酸，六亚甲基二胺和1,6-己二醇。

公开(公告)号：EP3155108A1

公开(公告)日：2017-04-19

申请号：EP15731478.2

申请日：2015-06-16

Applicant: Invista Technologies S.à.r.l.

Inventor： BOTES, Adriana Leonora ,  CONRADIE, Alex Van Eck ,  HADDOUCHE, Ramdane

IPC: C12P7/42 ,  C12P7/44

CPC classification number: C12P13/001 ,  C07C47/02 ,  C07C47/12 ,  C07C59/01 ,  C07C59/325 ,  C07C223/02 ,  C08G63/06 ,  C12N9/0008 ,  C12N9/0077 ,  C12N9/1007 ,  C12N9/1096 ,  C12P7/24 ,  C12P7/40 ,  C12P7/42 ,  C12P7/44 ,  C12P7/62 ,  C12P7/6409 ,  C12P7/6436 ,  C12Y102/99006 ,  C12Y114/15001 ,  C12Y114/15003 ,  C12Y206/01018 ,  C12Y206/01019 ,  C12Y206/01029 ,  C12Y206/01048 ,  C12Y206/01082

Abstract: This document describes biochemical pathways for producing 7-hydroxyheptanoate methyl ester and heptanoic acid heptyl ester using one or more of a fatty acid O-methyltransferase, an alcohol O-acetyltransferase, and a monooxygenase, as well as recombinant hosts expressing one or more of such exogenous enzymes. 7-hydroxyheptanoate methyl esters and heptanoic acid heptyl esters can be enzymatically converted to pimelic acid, 7-aminoheptanoate, 7-hydroxyheptanoate, heptamethylenediamine, or 1,7-heptanediol.