-
公开(公告)号：WO2015195682A1
公开(公告)日：2015-12-23
申请号：PCT/US2015/036057
申请日：2015-06-16
Applicant: INVISTA TECHNOLOGIES S.À.R.L.
Inventor： BOTES, Adriana Leonora , CONRADIE, Alex Van Eck , HADDOUCHE, Ramdane
CPC classification number: C12P13/001 , C07C47/02 , C07C47/12 , C07C59/01 , C07C59/325 , C07C223/02 , C08G63/06 , C12N9/0008 , C12N9/0077 , C12N9/1007 , C12N9/1096 , C12P7/24 , C12P7/40 , C12P7/42 , C12P7/44 , C12P7/62 , C12P7/6409 , C12P7/6436 , C12Y102/99006 , C12Y114/15001 , C12Y114/15003 , C12Y206/01018 , C12Y206/01019 , C12Y206/01029 , C12Y206/01048 , C12Y206/01082
Abstract: This document describes biochemical pathways for producing 6- hydroxyhexanoate methyl ester and hexanoic acid hexyl ester using one or more of a fatty acid O-methyltransferase, an alcohol O-acetyltransferase and a monooxygenase , as well as recombinant hosts expressing one or more of such enzymes. 6-hydroxyhexanoate methyl esters and hexanoic acid hexyl ester can be enzymatically converted to adipic acid, adipate semialdehyde, 6-aminohexanoate, 6-hydroxyhexanoate, hexamethylenediamine, and 1,6-hexanediol.
Abstract translation: 该文献描述了使用一种或多种脂肪酸O-甲基转移酶，醇O-乙酰转移酶和单加氧酶产生6-羟基己酸甲酯和己酸己酯的生化途径，以及表达一种或多种这样的酶的重组宿主 。 6-羟基己酸甲酯和己酸己酯可以酶促转化为己二酸，己二酸半醛，6-氨基己酸，6-羟基己酸，六亚甲基二胺和1,6-己二醇。
-
公开(公告)号：WO2015195611A2
公开(公告)日：2015-12-23
申请号：PCT/US2015/035947
申请日：2015-06-16
Applicant: INVISTA TECHNOLOGIES S.À.R.L.
Inventor： BOTES, Adriana Leonora , CONRADIE, Alex Van Eck
CPC classification number: C12P7/62 , C07C69/533 , C12N9/0008 , C12N9/1029 , C12N9/1096 , C12N9/16 , C12N9/18 , C12P7/18 , C12P7/24 , C12P7/40 , C12P7/42 , C12P7/44 , C12P11/00 , C12P13/001 , C12P13/005 , C12P17/10 , C12Y102/99006 , C12Y203/01016 , C12Y206/01018 , C12Y206/01019 , C12Y206/01029 , C12Y206/01048 , C12Y206/01082 , C12Y301/01085 , C12Y301/02
Abstract: This document describes biochemical pathways for producing 2(E)-heptenedioyl-CoA methyl ester from precursors such as 2-oxo-glutarate, acetyl-CoA, or succinyl-CoA using one or more of a fatty acid O-methyltransferase, a thioesterase, a CoA-transferase, a CoA ligase , as well as recombinant hosts expressing one or more of such enzymes. 2(E)-heptenedioyl-CoA methyl ester can be enzymatically converted to pimeloyl-CoA using a trans-2-enoyl-CoA reductase , and a methylesterase . Pimeloyl-CoA can be enzymatically converted to pimelic acid, 7-aminoheptanoate, 7-hydroxyheptanoate, heptamethylenediamine, or 1,7-heptanediol.
Abstract translation: 本文件描述了使用一种或多种脂肪酸O-甲基转移酶，硫酯酶，硫酸酯酶等从前体例如2-氧代 - 戊二酸，乙酰辅酶A或琥珀酰-CoA制备2（E） - 庚二酰辅酶A甲酯的生化途径， CoA转移酶，CoA连接酶，以及表达一种或多种这样的酶的重组宿主。 2（E） - 庚二酰辅酶A甲酯可以使用反式-2-烯酰辅酶A还原酶和甲酯酶酶转化为双甲酰基-CoA。 可将Pimeloyl-CoA酶促转化成庚二酸，7-氨基庚酸酯，7-羟基庚酸酯，七亚甲基二胺或1,7-庚二醇。
-
Patent Agency Ranking3.发明公开METHODS OF PRODUCING 7-CARBON CHEMICALS FROM LONG CHAIN FATTY ACIDS VIA OXIDATIVE CLEAVAGE 审中-公开PROCESS FOR通过氧化裂解PRODUCING 7 - 碳CHEMICALS长链脂肪酸
公开(公告)号：EP2938732A1
公开(公告)日：2015-11-04
申请号：EP13824254.0
申请日：2013-12-23
Applicant: Invista Technologies S.à.r.l.
Inventor： BOTES, Adriana Leonora , CONRADIE, Alex Van Eck , CHEN, Changlin , PEARLMAN, Paul S.
CPC classification number: C12P7/46 , C12P7/18 , C12P7/42 , C12P7/44 , C12P13/001 , C12P13/005
Abstract: This document describes biochemical pathways for producing pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl group, in a C7 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on the fatty acid synthesis pathway and oxidative cleavage of long chain acyl-[acp] intermediates by a monooxgenase (e.g., cytochrome P450) such as that encoded by BioI from microorganisms such as Bacillus subtillis.
-
4.发明公开PROCESS FOR PRODUCING GLUTARATE AND GLUTARIC ACID METHYL ESTER 审中-公开VERFAHREN ZUR HERSTELLUNG VON GLUTARAT- UNDGLUTARSÄUREMETHYLESTER
公开(公告)号：EP3155112A1
公开(公告)日：2017-04-19
申请号：EP15731807.2
申请日：2015-06-16
Applicant: Invista Technologies S.à.r.l.
Inventor： BOTES, Adriana Leonora , CONRADIE, Alex Van Eck
CPC classification number: C12P7/62 , C07C69/42 , C07C229/08 , C12N9/0008 , C12N9/1007 , C12N9/1096 , C12N9/16 , C12N9/18 , C12N15/52 , C12P7/42 , C12P7/44 , C12P13/001 , C12Y102/99006 , C12Y201/01197 , C12Y206/01018 , C12Y206/01038 , C12Y301/01085
Abstract: This document describes biochemical pathways for producing glutaric acid, 5-aminopentanoic acid, 5-hydroxypentanoic acid, cadaverine or 1,5-pentanediol by forming one or two terminal functional groups, comprised of carboxyl, amine or hydroxyl group, in a C5 backbone substrate such as malonyl-CoA or malonyl-[acp].
Abstract translation: 本文件描述了通过在C5主链基质如戊二酰辅酶A，戊二酰 - [acp]或戊二酸甲酯中形成一个或两个由羧基或羟基组成的末端官能团来生产2,4-戊二烯酰辅酶A的生化途径 。 2,4-戊二烯酰辅酶A可以酶促转化为1,3-丁二烯。
-
5.发明公开METHODS, REAGENTS AND CELLS FOR BIOSYNTHESIZING COMPOUND 审中-公开VERFAHREN，REENENZIEN UND ZELLEN ZUR BIOSYNEESE EINER VERBINDUNG
公开(公告)号：EP3155106A2
公开(公告)日：2017-04-19
申请号：EP15795047.8
申请日：2015-06-16
Applicant: Invista Technologies S.à.r.l.
Inventor： BOTES, Adriana Leonora , CONRADIE, Alex Van Eck
CPC classification number: C12P7/62 , C07C69/533 , C12N9/0008 , C12N9/1029 , C12N9/1096 , C12N9/16 , C12N9/18 , C12P7/18 , C12P7/24 , C12P7/40 , C12P7/42 , C12P7/44 , C12P11/00 , C12P13/001 , C12P13/005 , C12P17/10 , C12Y102/99006 , C12Y203/01016 , C12Y206/01018 , C12Y206/01019 , C12Y206/01029 , C12Y206/01048 , C12Y206/01082 , C12Y301/01085 , C12Y301/02
Abstract: This document describes biochemical pathways for producing 2(E)-heptenedioyl-CoA methyl ester from precursors such as 2-oxo-glutarate, acetyl-CoA, or succinyl-CoA using one or more of a fatty acid O-methyltransferase, a thioesterase, a CoA-transferase, a CoA ligase, as well as recombinant hosts expressing one or more of such enzymes. 2(E)-heptenedioyl-CoA methyl ester can be enzymatically converted to pimeloyl-CoA using a trans-2-enoyl-CoA reductase, and a methylesterase. Pimeloyl-CoA can be enzymatically converted to pimelic acid, 7-aminoheptanoate, 7-hydroxyheptanoate, heptamethylenediamine, or 1,7-heptanediol.
Abstract translation: 本文件描述了使用一种或多种脂肪酸O-甲基转移酶，硫酯酶，辅酶A转移酶和辅酶A连接酶从前体例如2-氧戊二酸生产2,3-脱氢腺苷酰辅酶A甲酯的生物化学途径，以及 表达一种或多种此类酶的重组宿主。 2,3-脱氢腺苷酰辅酶A甲酯可以使用反式-2-烯酰辅酶A还原酶酶促转化成己二酰辅酶A，甲酯酶又可以酶促转化为己二酸，6-氨基己酸6-羟基己酸酯 ，己内酰胺，六亚甲基二胺或1,6-己二醇。
-
公开(公告)号：EP3155108A1
公开(公告)日：2017-04-19
申请号：EP15731478.2
申请日：2015-06-16
Applicant: Invista Technologies S.à.r.l.
Inventor： BOTES, Adriana Leonora , CONRADIE, Alex Van Eck , HADDOUCHE, Ramdane
CPC classification number: C12P13/001 , C07C47/02 , C07C47/12 , C07C59/01 , C07C59/325 , C07C223/02 , C08G63/06 , C12N9/0008 , C12N9/0077 , C12N9/1007 , C12N9/1096 , C12P7/24 , C12P7/40 , C12P7/42 , C12P7/44 , C12P7/62 , C12P7/6409 , C12P7/6436 , C12Y102/99006 , C12Y114/15001 , C12Y114/15003 , C12Y206/01018 , C12Y206/01019 , C12Y206/01029 , C12Y206/01048 , C12Y206/01082
Abstract: This document describes biochemical pathways for producing 7-hydroxyheptanoate methyl ester and heptanoic acid heptyl ester using one or more of a fatty acid O-methyltransferase, an alcohol O-acetyltransferase, and a monooxygenase, as well as recombinant hosts expressing one or more of such exogenous enzymes. 7-hydroxyheptanoate methyl esters and heptanoic acid heptyl esters can be enzymatically converted to pimelic acid, 7-aminoheptanoate, 7-hydroxyheptanoate, heptamethylenediamine, or 1,7-heptanediol.
-
公开(公告)号：EP3155107A1
公开(公告)日：2017-04-19
申请号：EP15730679.6
申请日：2015-06-16
Applicant: Invista Technologies S.à.r.l.
Inventor： BOTES, Adriana Leonora , CONRADIE, Alex Van Eck
CPC classification number: C12P13/001 , C08G69/26 , C12N9/00 , C12N9/0008 , C12N9/1096 , C12N15/52 , C12P7/18 , C12P7/40 , C12P7/42 , C12P7/44 , C12P7/62 , C12P13/04 , C12Y102/99006 , C12Y206/01018
Abstract: This document describes biochemical pathways for producing glutaric acid, 5-aminopentanoic acid, 5-hydroxypentanoic acid, cadaverine or 1,5-pentanediol by forming one or two terminal functional groups, comprised of carboxyl, amine or hydroxyl group, in a C5 backbone substrate such as 2-oxoglutarate, the substrate being 2-oxo-adipate.
Abstract translation: 该文献描述了通过在C5骨架底物中形成包含羧基，胺或羟基的一个或两个末端官能团来生产戊二酸，5-氨基戊酸，5-羟基戊酸，尸胺或1,5-戊二醇的生物化学途径 如2-酮戊二酸。
-
-
-
-
-
-
Search Results
7
records
(took 0.026 seconds)
