公开(公告)号：EP2586596B1

公开(公告)日：2017-08-09

申请号：EP11797981.5

申请日：2011-06-07

Applicant: Japan Science and Technology Agency

Inventor： IKUTA Koji ,  IKEUCHI Masashi

IPC: B29C67/00 ,  B81C1/00 ,  A61M37/00

CPC classification number: B29C67/0081 ,  A61M2037/0023 ,  A61M2037/0053 ,  B29C64/135 ,  B29L2031/7544 ,  B33Y10/00 ,  B33Y70/00 ,  B81B2201/055 ,  B81C1/00373 ,  B81C2201/0188 ,  Y10T428/2933 ,  Y10T428/31678

公开(公告)号：EP2618197A1

公开(公告)日：2013-07-24

申请号：EP11824911.9

申请日：2011-07-27

Applicant: Japan Science and Technology Agency

Inventor： IKUTA Koji ,  IKEUCHI Masashi

IPC: G02B21/00 ,  G02B21/32 ,  G02B21/36

CPC classification number: G02B21/367 ,  B33Y80/00 ,  G02B21/006 ,  G02B21/0076 ,  G02B21/32 ,  G02B21/365

Abstract: Provided is a 3-dimensional confocal microscopy apparatus which is manufactured by combining a confocal microscope and an optical tweezers technique, wherein a pair of lenses for focal plane displacement where one lens is movable in the optical axis direction is arranged between a fixed objective lens and a fluorescent light imaging camera, and the 3-dimensional confocal microscopy apparatus also includes a mean which corrects the aberration of a fluorescent confocal image obtained by the fluorescent imaging camera. Accordingly, it is possible to provide a 3-dimensional confocal microscopy apparatus which can acquire a 3-dimensional image of a specimen during a manipulation of the specimen using optical tweezers without affecting an optical trap.

公开(公告)号：EP2586596A1

公开(公告)日：2013-05-01

申请号：EP11797981.5

申请日：2011-06-07

Applicant: Japan Science and Technology Agency

Inventor： IKUTA Koji ,  IKEUCHI Masashi

IPC: B29C67/00

CPC classification number: B29C67/0081 ,  A61M2037/0023 ,  A61M2037/0053 ,  B29C64/135 ,  B29L2031/7544 ,  B33Y10/00 ,  B33Y70/00 ,  B81B2201/055 ,  B81C1/00373 ,  B81C2201/0188 ,  Y10T428/2933 ,  Y10T428/31678

Abstract: Disclosed is a method for producing a three-dimensional polymer-metal complex microstructure including forming a polymer structure by stereolithography using a photocurable resin having a reactive group X and dipping it in a liquid of a metal-containing nanoparticle having a reactive group X' which is bound to the reactive group X, thereby forming a metal-containing layer on the polymer structure through binding the reactive group X and the reactive group X'.
According to this method, it is possible to produce a polymer-metal complex structure having a steric structure and to produce a three-dimensional polymer-metal complex microstructure which does not denature biomolecules in a metal complexation process.