公开(公告)号：AU763413B2

公开(公告)日：2003-07-24

申请号：AU2723600

申请日：2000-01-11

Applicant: MEDISPECTRA INC

Inventor： MODELL MARK ,  HED ZE EV A ,  BEE DAVID ,  NORDSTROM ROBERT ,  KWO JENNIE ,  EMANS MATTHEW ,  LIPSON DAVID

IPC: G01N21/64 ,  A61B1/00 ,  A61B5/00 ,  G01N21/47

公开(公告)号：CA2356623C

公开(公告)日：2005-10-18

申请号：CA2356623

申请日：1999-12-22

Applicant: MEDISPECTRA INC

Inventor： NORDSTROM ROBERT ,  ZELENCHUK ALEXANDER ,  MODELL MARK

IPC: G01N21/64 ,  A61B1/04 ,  A61B5/00 ,  A61B6/00 ,  A61B10/00 ,  G01N20060101 ,  G01N21/17 ,  G01N21/27 ,  G01N21/33 ,  G01N21/47

Abstract: The present invention relates to systems and methods for examining a sample using a substantially monostatic, substantially confocal optical system comprising transmitting optics that focus an illuminating Lig ht upon the sample and receiving optics that collect light emitted from the sample following illumination thereof. In certain embodiments, the receiving optics may be arranged circumferentially around the light path traversed by the illuminating light. In certain embodiments, vide o apparatus may be included to produce images or to align the system in proximity to the target tissue. The systems and methods of the present invention may be directed towards the examination of a body tissue to provide a medical diagnosis.

公开(公告)号：AU760402B2

公开(公告)日：2003-05-15

申请号：AU2959600

申请日：1999-12-23

Applicant: MEDISPECTRA INC

Inventor： NORDSTROM ROBERT ,  MODELL MARK

IPC: G01N21/64 ,  A61B5/00 ,  A61B10/00 ,  G01N21/27 ,  G01N21/35

Abstract: A method and a system is provided for discriminating between healthy cervical tissue and pathologic cervical tissue based on the fluorescence response of the tissue to laser excitation (LIF) and the backscatter response to illumination by white light (in the spectral range of 360 to 750 nm). Combining LIF and white light responses, as well as evaluating a spatial correlation between proximate cervical tissue sites in conjunction with a statistically significant "distance" algorithm, such as the Mahalanobis distance between data sets, can improve the discrimination between normal and abnormal tissue. The results may be displayed in the form of a map of the cervix representing the suspected pathology.

公开(公告)号：AU2959600A

公开(公告)日：2000-07-12

申请号：AU2959600

申请日：1999-12-23

Applicant: MEDISPECTRA INC

Inventor： NORDSTROM ROBERT ,  MODELL MARK

IPC: G01N21/64 ,  A61B5/00 ,  A61B10/00 ,  G01N21/27 ,  G01N21/35

Abstract: A method and a system is provided for discriminating between healthy cervical tissue and pathologic cervical tissue based on the fluorescence response of the tissue to laser excitation (LIF) and the backscatter response to illumination by white light (in the spectral range of 360 to 750 nm). Combining LIF and white light responses, as well as evaluating a spatial correlation between proximate cervical tissue sites in conjunction with a statistically significant "distance" algorithm, such as the Mahalanobis distance between data sets, can improve the discrimination between normal and abnormal tissue. The results may be displayed in the form of a map of the cervix representing the suspected pathology.

公开(公告)号：CA2356623A1

公开(公告)日：2000-06-29

申请号：CA2356623

申请日：1999-12-22

Applicant: MEDISPECTRA INC

Inventor： MODELL MARK ,  NORDSTROM ROBERT ,  ZELENCHUK ALEXANDER

IPC: G01N21/64 ,  A61B1/04 ,  A61B5/00 ,  A61B6/00 ,  A61B10/00 ,  G01N20060101 ,  G01N21/17 ,  G01N21/27 ,  G01N21/33 ,  G01N21/47

Abstract: The present invention relates to systems and methods for examining a sample using a substantially monostatic, substantially confocal optical system comprising transmitting optics that focus an illuminating light upon the sample and receiving optics that collect light emitted from the sample following illumination thereof. In certain embodiments, the receiving optics may be arranged circumferentially around the light path traversed by the illuminating light. In certain embodiments, video apparatus may be included to produce images or to align the system in proximity to the target tissue. The systems and methods of the present invention may be directed towards the examination of a body tissue to provide a medical diagnosis.

公开(公告)号：WO0037917A3

公开(公告)日：2001-08-23

申请号：PCT/US9931001

申请日：1999-12-22

Applicant: MEDISPECTRA INC ,  NORDSTROM ROBERT ,  MODELL MARK ,  ZELENCHUK ALEXANDER

Inventor： NORDSTROM ROBERT ,  MODELL MARK ,  ZELENCHUK ALEXANDER

IPC: G01N21/64 ,  A61B1/04 ,  A61B5/00 ,  A61B6/00 ,  A61B10/00 ,  G01N20060101 ,  G01N21/17 ,  G01N21/27 ,  G01N21/33 ,  G01N21/47

CPC classification number: A61B5/0059 ,  A61B5/0068

Abstract: The present invention relates to systems and methods for examining a sample using a substantially monostatic, substantially confocal optical system comprising transmitting optics that focus an illuminating light upon the sample and receiving optics that collect light emitted from the sample following illumination thereof. In certain embodiments, the receiving optics may be arranged circumferentially around the light path traversed by the illuminating light. In certain embodiments, video apparatus may be included to produce images or to align the system in proximity to the target tissue. The systems and methods of the present invention may be directed towards the examination of a body tissue to provide a medical diagnosis.

公开(公告)号：WO0074556A3

公开(公告)日：2001-07-12

申请号：PCT/US0016014

申请日：2000-06-09

Applicant: MEDISPECTRA INC

Inventor： NORDSTROM ROBERT ,  BEE DAVID ,  MODELL MARK ,  HED ZE EV ,  KWO JENNIE ,  EMANS MATTHEW

IPC: A61B1/00 ,  A61B19/00 ,  A61B5/00

CPC classification number: A61B1/00062 ,  A61B1/00059 ,  A61B1/00082 ,  A61B1/00096 ,  A61B1/00103 ,  A61B1/00135 ,  A61B1/00142 ,  A61B1/043 ,  A61B5/0084 ,  A61B2090/0814 ,  A61B2562/08

Abstract: The present invention recognizes that optical probes function both as medical access devices and as instruments which collect complex optical data. The invention provides an optical probe accessory device which can access luminal spaces within the body of a patient without sacrificing the quality of optical data obtained. The accessory device further comprises either, singly, or in combination, selectable features or options which optimize light transmission, maximize patient comfort, and provide single-use capabilities.

Abstract translation: 本发明认识到，光学探针既用作医疗接入装置，也用作收集复杂光学数据的仪器。 本发明提供一种光学探针附件装置，其可以在不牺牲所获得的光学数据的质量的情况下访问患者体内的腔室空间。 附件设备还包括单独地或组合地可选择的特征或选项，其优化光透射，使患者舒适度最大化并提供一次性使用能力。

公开(公告)号：AU2003254731B2

公开(公告)日：2006-04-27

申请号：AU2003254731

申请日：2003-10-15

Applicant: MEDISPECTRA INC

Inventor： LIPSON DAVID ,  NORDSTROM ROBERT ,  HED ZE EV A ,  EMANS MATTHEW ,  KWO JENNIE ,  MODELL MARK ,  BEE DAVID

IPC: A61B1/00 ,  G01N21/64 ,  A61B5/00 ,  G01N21/47

公开(公告)号：AU768940B2

公开(公告)日：2004-01-08

申请号：AU5332300

申请日：2000-06-09

Applicant: MEDISPECTRA INC

Inventor： NORDSTROM ROBERT ,  BEE DAVID ,  MODELL MARK ,  HED ZE EV ,  KWO JENNIE ,  EMANS MATTHEW

IPC: A61B1/00 ,  A61B19/00

公开(公告)号：AU759282B2

公开(公告)日：2003-04-10

申请号：AU2715300

申请日：1999-12-22

Applicant: MEDISPECTRA INC

Inventor： NORDSTROM ROBERT ,  MODELL MARK ,  ZELENCHUK ALEXANDER

IPC: G01N21/64 ,  A61B1/04 ,  A61B5/00 ,  A61B6/00 ,  A61B10/00 ,  G01N20060101 ,  G01N21/17 ,  G01N21/27 ,  G01N21/33 ,  G01N21/47

Abstract: The present invention relates to systems and methods for examining a sample using a substantially monostatic, substantially confocal optical system comprising transmitting optics that focus an illuminating light upon the sample and receiving optics that collect light emitted from the sample following illumination thereof. In certain embodiments, the receiving optics may be arranged circumferentially around the light path traversed by the illuminating light. In certain embodiments, video apparatus may be included to produce images or to align the system in proximity to the target tissue. The systems and methods of the present invention may be directed towards the examination of a body tissue to provide a medical diagnosis.