公开(公告)号：MX2010010600A

公开(公告)日：2011-03-30

申请号：MX2010010600

申请日：2009-03-27

Applicant: PACIFIC BIOSCIENCES CALIFORNIA INC

Inventor： TURNER STEPHEN ,  TRAVERS KEVIN ,  OTTO GEOFF ,  HEINER CHERYL ,  MA CONGCONG

IPC: C12Q1/68

Abstract: Se describen composiciones y métodos para secuenciación de ácido nucleico que incluyen constructos de plantilla que comprenden porciones de doble hebra en constructos parcial o completamente contiguos, para proveer determinación de secuencia redundante por medio de una o ambas de secuenciación de hebras de sentido y anti-sentido y secuenciación iterativamente de todo el constructo múltiples veces. Componentes de secuencia adicionales son también incluidos opcionalmente dentro de tales constructos de plantilla. También se proveen métodos para el uso y preparación de estos constructor, también corno composiciones de secuenciación para su aplicación.

公开(公告)号：CA2991818A1

公开(公告)日：2009-10-01

申请号：CA2991818

申请日：2009-03-27

Applicant: PACIFIC BIOSCIENCES CALIFORNIA INC

Inventor： TRAVERS KEVIN ,  OTTO GEOFF ,  TURNER STEPHEN ,  HEINER CHERYL ,  MA CONGCONG

IPC: C12Q1/6869 ,  G16B30/00 ,  C12Q1/6806 ,  G16B30/10

Abstract: Compositions for nucleic acid sequencing are provided that include template constructs that comprise double stranded portions in partially or completely contiguous constructs, to provide for redundant sequence determination through one or both of sequencing sense and antisense strands, and iteratively sequencing the entire construct multiple times. Additional sequence components are also optionally included within such template constructs. Methods are also provided for the use and preparation of these constructs as well as sequencing compositions for their application.

公开(公告)号：CA2719747C

公开(公告)日：2018-02-20

申请号：CA2719747

申请日：2009-03-27

Applicant: PACIFIC BIOSCIENCES CALIFORNIA INC

Inventor： TRAVERS KEVIN ,  OTTO GEOFF ,  TURNER STEPHEN ,  HEINER CHERYL ,  MA CONGCONG

IPC: C12Q1/68 ,  C12Q1/6869

Abstract: Compositions and methods for nucleic acid sequencing include template constructs that comprise double stranded portions in a partially or completely contiguous constructs, to provide for redundant sequence determination through one or both of sequencing sense and antisense strands, and iteratively sequencing the entire construct multiple times. Additional sequence components are also optionally included within such template constructs. Methods are also provided for the use and preparation of these constructs as well as sequencing compositions for their application.

公开(公告)号：AU2015202111B9

公开(公告)日：2017-07-27

申请号：AU2015202111

申请日：2015-04-24

Applicant: PACIFIC BIOSCIENCES CALIFORNIA INC

Inventor： TRAVERS KEVIN ,  OTTO GEOFF ,  TURNER STEPHEN ,  HEINER CHERYL ,  MA CONGCONG

IPC: C12Q1/68

Abstract: Compositions and methods for nucleic acid sequencing include template constructs that comprise double stranded portions in a partially or completely contiguous constructs, to provide for redundant sequence determination through one or both of sequencing sense and antisense strands, and iteratively sequencing the entire construct multiple times. Additional sequence components are also optionally included within such template constructs. Methods are also provided for the use and preparation of these constructs as well as sequencing compositions for their application.

公开(公告)号：CA2991818C

公开(公告)日：2022-10-11

申请号：CA2991818

申请日：2009-03-27

Applicant: PACIFIC BIOSCIENCES CALIFORNIA INC

Inventor： TRAVERS KEVIN ,  OTTO GEOFF ,  TURNER STEPHEN ,  HEINER CHERYL ,  MA CONGCONG

IPC: C12Q1/6869 ,  C12Q1/6806

Abstract: Compositions for nucleic acid sequencing are provided that include template constructs that comprise double stranded portions in partially or completely contiguous constructs, to provide for redundant sequence determination through one or both of sequencing sense and antisense strands, and iteratively sequencing the entire construct multiple times. Additional sequence components are also optionally included within such template constructs. Methods are also provided for the use and preparation of these constructs as well as sequencing compositions for their application.

公开(公告)号：AU2015202111B2

公开(公告)日：2017-03-16

申请号：AU2015202111

申请日：2015-04-24

Applicant: PACIFIC BIOSCIENCES CALIFORNIA INC

Inventor： TRAVERS KEVIN ,  OTTO GEOFF ,  TURNER STEPHEN ,  HEINER CHERYL ,  MA CONGCONG

IPC: C12Q1/68

公开(公告)号：AU2009229157B2

公开(公告)日：2015-01-29

申请号：AU2009229157

申请日：2009-03-27

Applicant: PACIFIC BIOSCIENCES CALIFORNIA INC

Inventor： MA CONGCONG ,  TURNER STEPHEN ,  TRAVERS KEVIN ,  HEINER CHERYL ,  OTTO GEOFF

IPC: C12Q1/68

Abstract: Compositions and methods for nucleic acid sequencing include template constructs that comprise double stranded portions in a partially or completely contiguous constructs, to provide for redundant sequence determination through one or both of sequencing sense and antisense strands, and iteratively sequencing the entire construct multiple times. Additional sequence components are also optionally included within such template constructs. Methods are also provided for the use and preparation of these constructs as well as sequencing compositions for their application.