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公开(公告)号：WO2004085064A2
公开(公告)日：2004-10-07
申请号：PCT/US0328190
申请日：2003-09-10
Applicant: WISCONSIN ALUMNI RES FOUND
Inventor： LAGALLY MAX G , LAL AMIT , LEE CHUNG HOON , LARSON BRADLEY J
CPC classification number: B01L3/0268 , B01J2219/00367 , B01J2219/00378 , B01J2219/00527 , B01J2219/00533 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00659 , B01J2219/00689 , B01J2219/00722 , B01L99/00 , B01L2300/0819 , B01L2300/0867 , B01L2400/0439 , C40B40/06 , C40B60/14 , G01N2035/1041
Abstract: Devices and methods for depositing fluids on substrates in patterns of spots, lines, or other features use a nozzle, which is preferably configured similarly to a micropipette, having a piezoelectric crystal or other ultrasonic actuator coupled to one of its sides. The nozzle may be charged via capillary action by dipping it into a well containing the fluid to be deposited, and may then be positioned over a desired area of a substrate, at which point activation of the ultrasonic actuator at ultrasonic frequencies will eject the fluid onto the substrate. The needle may subsequently be dipped into a well of rinsing fluid for cleaning. Spots or lines on the order of 5 micrometers width may be generated, making the invention particularly suitable for use in biological applications such as microarray production and in microelectronics applications such as the printing of organic circuitry.
Abstract translation: 用于以点，线或其他特征的图案将流体沉积在基底上的装置和方法使用喷嘴，该喷嘴优选与微量移液管类似地配置，具有耦合到其一侧的压电晶体或其他超声致动器。 通过将喷嘴浸入含有要沉积的流体的孔中，可以通过毛细管作用对喷嘴进行充电，然后可以将喷嘴定位在基底的期望区域上，在超声频率下激活超声致动器将喷射流体到 衬底。 随后可将针浸入冲洗液的一个井中以进行清洁。 可产生大约5微米宽度的点或线，使得本发明特别适用于生物应用，例如微阵列生产和微电子应用，例如有机电路印刷。
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公开(公告)号：WO03045837A2
公开(公告)日：2003-06-05
申请号：PCT/US0237503
申请日：2002-11-22
Applicant: WISCONSIN ALUMNI RES FOUND
Inventor： LAL AMIT , LAGALLY MAX G , LEE CHUNG-HOON , RUGHEIMER PAUL POWEL
IPC: B81B3/00 , B81C1/00 , H01L29/04 , H01L29/786 , H01L29/80 , H01L29/82 , H01L31/036 , H01L31/112
CPC classification number: B81C1/00666 , B81C2201/0167 , B82Y10/00 , B82Y30/00 , H01L29/78603 , H01L29/78639 , Y10S438/962
Abstract: A suspended semiconductor film is anchored to a substrate at at least two opposed anchor positions, and film segments are deposited on the semiconductor film adjacent to one or more of the anchor positions to apply either tensile or compressive stress to the semiconductor film between the film segments. A crystalline silicon film may be anchored to the substrate and have tensile stress applied thereto to reduce the lattice mismatch between the silicon and a silicon-germanium layer deposited onto the silicon film. By controlling the level of stress in the silicon film, the size, density and distribution of quantum dots formed in a high germanium content silicon-germanium film deposited on the silicon film can be controlled.
Abstract translation: 悬浮的半导体膜在至少两个相对的锚定位置处锚定到基底上，并且将薄膜段沉积在与一个或多个锚定位置相邻的半导体膜上，以将拉伸或压缩应力施加到膜段之间的半导体膜 。 结晶硅膜可以锚定到基底并且施加拉伸应力以减小硅和沉积在硅膜上的硅 - 锗层之间的晶格失配。 通过控制硅膜中的应力水平，可以控制沉积在硅膜上的高锗含量硅 - 锗膜中形成的量子点的尺寸，密度和分布。
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公开(公告)号：WO0205708A2
公开(公告)日：2002-01-24
申请号：PCT/US0121754
申请日：2001-07-11
Applicant: WISCONSIN ALUMNI RES FOUND
Inventor： LAL AMIT , LEE CHUNG-HOON
CPC classification number: A61B5/14514 , A61B5/150022 , A61B5/150083 , A61B5/150297 , A61B5/150389 , A61B5/150503 , A61B5/150946 , A61B5/150977 , A61B5/15142 , A61B2010/008 , A61B2017/00765 , A61M37/0092
Abstract: An ultrasonically driven pump, which may be used for sampling body fluids or atomizing liquids, has a stationary outer needle and an inner needle mounted within the bore of the outer needle. The distal end of the inner needle is positioned adjacent to the distal end of the outer needle. The inner needle is ultrasonically vibrated by an ultrasonic actuator without vibrating the outer needle, with resulting draw of liquid through the distal end of the outer needle into the bore of the inner needle for discharge through the proximal end of the inner needle. The outer needle can be formed to have a penetrating tip suited for penetrating the skin of a subject to allow sampling of body fluids including interstitial fluids. The pump can also be used for atomizing liquid, by drawing liquid from a supply that is pumped from the distal end to an open proximal end of the inner needle where the liquid is discharged by automization into the atmosphere.
Abstract translation: 可用于采样体液或雾化液体的超声波驱动泵具有固定的外针和安装在外针孔内的内针。 内针的远端定位在外针的远端附近。 通过超声波致动器使内针超声振动，而不振动外针，从而通过外针的远端将液体吸入内针的孔中，以通过内针的近端排出。 外针可以形成为具有适于穿透对象的皮肤的穿透尖端，以允许采集包括间质液的体液。 泵也可用于雾化液体，通过从从远端泵送到内针的打开的近端的供应源抽取液体，其中液体通过自动化排放到大气中。
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4.发明申请METHOD AND APPARATUS FOR STRESS PULSED RELEASE AND ACTUATION OF MICROMECHANICAL STRUCTURES 审中-公开应力脉冲释放的方法与装置及微观结构的实施
公开(公告)号：WO0075068A3
公开(公告)日：2001-07-12
申请号：PCT/US0014940
申请日：2000-06-01
Applicant: WISCONSIN ALUMNI RES FOUND
Inventor： LAL AMIT , KAAJAKARI VILLE
CPC classification number: G02B6/3578 , B81C1/00968 , G02B6/3512 , G02B6/3518 , G02B6/3546 , G02B6/357 , G02B6/3584 , G02B6/359 , H02N2/028 , H02N2/10
Abstract: Micromechanical parts are freed from a surface of a substrate to which the parts are stiction bonded by applying a pulse stress wave to the substrate that propagates through the substrate and is reflected at the surface to which the micropart is stiction bonded, breaking the bond between the micropart and the substrate surface by a spalling action at the surface. A piezoelectric transducer may be secured to the bottom surface of the substrate such that a voltage pulse supplied to the piezoelectric transducer deforms the piezoelectric element and the substrate to which it is secured to provide a pulse stress wave that propagates through the substrate to the top surface. For microparts that are in contact with but not stiction bonded to the substrate top surface, a pulse stress wave can be applied to the substrate to drive the microparts away from the surface by the rapid displacement of that surface as the pulse stress wave is reflected at the surface. Microparts that are attached to the surface in a way to permit rotation or a translation of movement may be activated by applying a pulse stress wave to the substrate to drive such parts away from contact with the surface into their erected positions.
Abstract translation: 通过向穿过衬底传播的衬底施加脉冲应力波而将微机械部件从衬底的表面上去除，该衬底通过施加脉冲应力波并在微粘结的表面上被反射，从而破坏了 微粒和表面上的剥落作用。 压电传感器可以固定到基板的底表面，使得提供给压电换能器的电压脉冲使压电元件和其所固定的基板变形，从而提供脉冲应力波，该脉冲应力波通过基板传播到顶表面 。 对于与衬底顶表面接触而不是静摩擦的微型零件，可以将脉冲应力波施加到衬底上，以随着脉冲应力波反射在该表面上的快速位移而驱动微组件离开表面 表面。 以允许旋转或平移运动的方式附接到表面的微孔可以通过向基板施加脉冲应力波来驱动这些部件远离与表面接触进入其竖立位置。
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公开(公告)号：DE60230533D1
公开(公告)日：2009-02-05
申请号：DE60230533
申请日：2002-02-08
Applicant: TYCO HEALTHCARE , WISCONSIN ALUMNI RES FOUND
Inventor： ARANYI ERNEST , CUNY DOUGLAS J , HEINRICH RUSSELL , LAL AMIT , LEWIS BILL , ROY PHIL
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Patent Agency Ranking
公开(公告)号：ES2346720T3
公开(公告)日：2010-10-19
申请号：ES08165099
申请日：2002-02-08
Applicant: TYCO HEALTHCARE , WISCONSIN ALUMNI RES FOUND
Inventor： ARANYI ERNEST , CUNY DOUGLAS J , HEINRICH RUSSEL , LAL AMIT , LEWIS BILL , ROY PHIL
Abstract: Un instrumento quirúrgico (12) que comprende: un mango (18) una porción (20) de cuerpo alargada que se extiende distalmente desde el mango, estando dimensionado y configurado el cuerpo alargado para pasar a través de una cánula u orificio de cuerpo; y un efector extremo (22) soportado en el extremo distal de la porción de cuerpo alargada; el efector extremo incluye un miembro ultrasónico (160) que tiene un transductor ultrasónico (106) y un miembro resonante (104), el miembro resonante está conectado de modo operativo al transductor e incluye una superficie (126) de funcionamiento configurada para efectuar la disección de tejidos, cortar, coagular, ligar y/o hemostasis, y además incluye un sensor colocado en el miembro ultrasónico para monitorizar una condición del tejido que va a ser operado, en el que la condición es la impedancia ultrasónica, la impedancia eléctrica y la temperatura.
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公开(公告)号：CA2437582C
公开(公告)日：2009-09-15
申请号：CA2437582
申请日：2002-02-08
Applicant: TYCO HEALTHCARE , WISCONSIN ALUMNI RES FOUND
Inventor： ARANYI ERNEST , ROY PHIL , LEWIS BILL , CUNY DOUGLAS J , HEINRICH RUSSELL , LAL AMIT
Abstract: An ultrasonic surgical instrument is provided which includes a handle assemb ly (218), a body (220) extending distally form the handle assembly and an end effector (222) configured to effect cutting, dissection, coagulation and/or ligation of tissue. The end effector (222) includes an ultrasonic member (226). A transducer (32, 132) is supported adjacent, on or within the ultrasonic member (226) and is connected to a power source. Upon actuation o f Th. power source, the transducer (32, 132) effects vibration of the ultrason ic member (226). In one preferred embodiment, the end effector (222) is mounted for articulation about the distal end of the instrument.
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公开(公告)号：AU7332501A
公开(公告)日：2002-01-30
申请号：AU7332501
申请日：2001-07-11
Applicant: WISCONSIN ALUMNI RES FOUND
Inventor： LAL AMIT , LEE CHUNG-HOON
Abstract: An ultrasonically driven pump, which may be used for sampling body fluids or atomizing liquids, has a stationary outer needle and an inner needle mounted within the bore of the outer needle. The distal end of the inner needle is positioned adjacent to the distal end of the outer needle. The inner needle is ultrasonically vibrated by an ultrasonic actuator without vibrating the outer needle, with resulting draw of liquid through the distal end of the outer needle into the bore of the inner needle for discharge through the proximal end of the inner needle. The outer needle can be formed to have a penetrating tip suited for penetrating the skin of a subject to allow sampling of body fluids including interstitial fluids. The pump can also be used for atomizing liquid, by drawing liquid from a supply that is pumped from the distal end to an open proximal end of the inner needle where the liquid is discharged by atomization into the atmosphere.
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公开(公告)号：CA2437582A1
公开(公告)日：2002-08-15
申请号：CA2437582
申请日：2002-02-08
Applicant: TYCO HEALTHCARE , WISCONSIN ALUMNI RES FOUND
Inventor： HEINRICH RUSSELL , CUNY DOUGLAS J , ARANYI ERNEST , LAL AMIT , LEWIS BILL , ROY PHIL
Abstract: An ultrasonic surgical instrument is provided which includes a handle assemb ly (218), a body (220) extending distally form the handle assembly and an end effector (222) configured to effect cutting, dissection, coagulation and/or ligation of tissue. The end effector (222) includes an ultrasonic member (226). A transducer (32, 132) is supported adjacent, on or within the ultrasonic member (226) and is connected to a power source. Upon actuation o f Th. power source, the transducer (32, 132) effects vibration of the ultrason ic member (226). In one preferred embodiment, the end effector (222) is mounted for articulation about the distal end of the instrument.
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10.发明专利
公开(公告)号：AU5307400A
公开(公告)日：2000-12-28
申请号：AU5307400
申请日：2000-06-01
Applicant: WISCONSIN ALUMNI RES FOUND
Inventor： LAL AMIT , KAAJAKARI VILLE
Abstract: Micromechanical parts are freed from a surface of a substrate to which the parts are stiction bonded by applying a pulse stress wave to the substrate that propagates through the substrate and is reflected at the surface to which the micropart is stiction bonded, breaking the bond between the micropart and the substrate surface by a spalling action at the surface. A piezoelectric transducer may be secured to the bottom surface of the substrate such that a voltage pulse supplied to the piezoelectric transducer deforms the piezoelectric element and the substrate to which it is secured to provide a pulse stress wave that propagates through the substrate to the top surface. For microparts that are in contact with but not stiction bonded to the substrate top surface, a pulse stress wave can be applied to the substrate to drive the microparts away from the surface by the rapid displacement of that surface as the pulse stress wave is reflected at the surface. Microparts that are attached to the surface in a way to permit rotation or a translation of movement may be activated by applying a pulse stress wave to the substrate to drive such parts away from contact with the surface into their erected positions.
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