Scanner type fluorescence detection apparatus for treating numerous samples
    2.
    发明授权
    Scanner type fluorescence detection apparatus for treating numerous samples 失效
    用于处理多种样品的扫描仪型荧光检测装置

    公开(公告)号:US06396581B1

    公开(公告)日:2002-05-28

    申请号:US09492302

    申请日:2000-01-27

    Abstract: A fluorescence detection apparatus is provided which comprises a sample holder for holding stationarily sample vessels deployed along a circle line or concentric circle lines having different radiuses, a partition plate connected to a driving means to be rotatable around the center of the circle line or concentric circle lines, an optical means for excitation light and an optical means for fluorescence light fixed respectively to the partition plate to be rotatable in integration therewith, a first light guide constituted of numerous optical fibers, a photosensor, and a light source for generating the excitation light, wherein the partition plate, the optical means for excitation light, and the optical means for fluorescence are integrally rotated, and thereby the fluorescence of the sample arranged along the circle line is successively detected and the detected fluorescence is transmitted to the photosensor. This fluorescence detection apparatus is useful in real-time monitoring of fluorescence signals, and satisfies the requirements of precise temperature control, quick treatment of many samples, high sensitivity, high reliability, low cost, and small size of the apparatus.

    Abstract translation: 提供了一种荧光检测装置,其包括用于保持沿着圆线展开的固定样品容器的样本保持器或具有不同半径的同心圆线,连接到驱动装置的分隔板,以可围绕圆线或同心圆的中心旋转 线路,用于激发光的光学装置和用于荧光的光学装置分别固定在分隔板上以使其一体旋转;由多个光纤构成的第一导光体,光电传感器和用于产生激发光的光源 其中分隔板,用于激发光的光学装置和用于荧光的光学装置一体地旋转,从而连续检测沿着圆线排列的样品的荧光,并将检测到的荧光传输到光电传感器。 该荧光检测装置可用于实时监测荧光信号,满足精密温度控制,快速处理多种样品,高灵敏度,高可靠性,低成本,体积小的要求。

    Multipoint measurement system and method
    3.
    发明申请
    Multipoint measurement system and method 审中-公开
    多点测量系统及方法

    公开(公告)号:US20040189979A1

    公开(公告)日:2004-09-30

    申请号:US10486584

    申请日:2004-02-11

    Abstract: There is presented a multipoint measurement system comprising light sources (1, 2); a plurality of illuminating fibers (5, 6) for transmitting light from the light sources to a sample so as to illuminate a plurality of points of the sample (A, B); a plurality of receiving fibers (8, 9) for collecting light beams including transmitted, reflected, scattered light beams at the plurality of points; a beam selector (10) which comprises a rotatable disk (12) having an aperture for transmitting a light beam collected by one of the plurality of receiving fibers (8, 9) through the receiving fiber (11); and an MCPD (4). When the rotatable disk (12) is rotated so that the aperture is displaced to and stops at a position at which light at the desired channel passes through, it is possible to perform measurement only on the light passing through the corresponding receiving fiber (8, 9, 11). Light at any other channel may be measured by rotating the rotatable disk (12) by a predetermined angle.

    Abstract translation: 提出了包括光源(1,2)的多点测量系统; 多个照明光纤(5,6),用于将来自所述光源的光透射到样品以照射所述样品(A,B)的多个点; 多个接收光纤(8,9),用于在多个点处收集包括透射的,反射的散射光束的光束; 光束选择器(10),其包括具有用于透射通过所述接收光纤(11)从所述多个接收光纤(8,9)之一收集的光束的孔的可旋转盘(12)。 和一个MCPD(4)。 当可旋转盘(12)旋转使得孔径移动到并停止在期望通道上的光通过的位置时,可以仅对通过相应的接收光纤(8,8)的光进行测量, 9,11)。 可以通过将可旋转盘(12)旋转预定角度来测量任何其它通道处的光。

    Multiple-sample scanner-type fluorescence detection apparatus
    4.
    发明公开
    Multiple-sample scanner-type fluorescence detection apparatus 有权
    Abtastende FluoreszenznachweisvorrichtungfürMehrfachproben。

    公开(公告)号:EP1024355A1

    公开(公告)日:2000-08-02

    申请号:EP00101404.2

    申请日:2000-01-25

    Abstract: A fluorescence detection apparatus is provided which comprises a sample holder (4) for holding stationarily sample vessels deployed along a circle line or concentric circle lines having different radiuses, a partition plate (3) connected to a driving means (7) to be rotatable around the center of the circle line or concentric circle lines, optical means (5) for excitation light and optical means (6) for fluorescence light fixed respectively to the partition plate to be rotatable in integration therewith, a first light guide (1) constituted of numerous optical fibers, a photosensor (2), and a light source (8) for generating the excitation light, wherein the partition plate, the optical means for excitation light, and the optical means for fluorescence are integrally rotated, and thereby the fluorescence of the sample arranged along the circle line is successively detected and the detected fluorescence is transmitted to the photosensor. This fluorescence detection apparatus is useful in real-time monitoring of fluorescence signals, and satisfies the requirements of precise temperature control, quick treatment of many samples, high sensitivity, high reliability, low cost, and small size of the apparatus.

    Abstract translation: 提供了一种荧光检测装置,其包括用于保持沿着圆线展开的固定样品容器的样本保持器(4)或具有不同半径的同心圆线;连接到驱动装置(7)以可旋转的分隔板(3) 圆线或同心圆线的中心,用于激发光的光学装置(5)和用于荧光的光学装置(6),分别固定在分隔板上以与其一体旋转;第一光导(1),由 多个光纤,光电传感器(2)和用于产生激发光的光源(8),其中分隔板,用于激发光的光学装置和用于荧光的光学装置一体地旋转,由此荧光 连续检测沿圆线排列的样品,并将检测到的荧光传输到光电传感器。 该荧光检测装置可以实时监测荧光信号,满足精密温度控制,快速处理多种样品,高灵敏度,高可靠性,低成本,小尺寸等要求。

    MULTIPOINT MEASUREMENT SYSTEM AND METHOD
    6.
    发明申请
    MULTIPOINT MEASUREMENT SYSTEM AND METHOD 审中-公开
    多点测量系统和方法

    公开(公告)号:WO2003083456A1

    公开(公告)日:2003-10-09

    申请号:PCT/JP2003/003497

    申请日:2003-03-24

    Abstract: There is presented a multipoint measurement system comprising light sources (1, 2) ; a plurality of illuminating fibers (5, 6) for transmitting light from the light sources to a sample so as to illuminate a plurality of points of the sample (A, B) ; a plurality of receiving fibers (8, 9) for collecting light beams including transmitted, reflected, scattered light beams at the plurality of points; a beam selector (10) which comprises a rotatable disk (12) having an aperture for transmitting a light beam collected by one of the plurality of receiving fibers (8, 9) through the receiving fiber (11) ; and an MCPD (4) . When the rotatable disk (12) is rotated so that the aperture is displaced to and stops at a position at which light at the desired channel passes through, it is possible to perform measurement only on the light passing through the corresponding receiving fiber (8, 9, 11) . Light at any other channel may be measured by rotating the rotatable disk (12) by a predetermined angle.

    Abstract translation: 提出了包括光源(1,2)的多点测量系统; 多个照明光纤(5,6),用于将来自所述光源的光透射到样品以照射所述样品(A,B)的多个点; 多个接收光纤(8,9),用于在多个点处收集包括透射的,反射的散射光束的光束; 光束选择器(10),其包括具有用于透射通过所述接收光纤(11)从所述多个接收光纤(8,9)之一收集的光束的孔的可旋转盘(12)。 和MCPD(4)。 当可旋转盘(12)旋转使得孔径移动到并停止在期望通道上的光通过的位置时,可以仅对通过相应的接收光纤(8,8)的光进行测量, 9,11)。 可以通过将可旋转盘(12)旋转预定角度来测量任何其它通道处的光。

    Apparatus and method for multipoint measurement
    8.
    发明专利
    Apparatus and method for multipoint measurement 审中-公开
    多点测量的装置和方法

    公开(公告)号:JP2003294609A

    公开(公告)日:2003-10-15

    申请号:JP2002095671

    申请日:2002-03-29

    Abstract: PROBLEM TO BE SOLVED: To provide a multipoint measuring apparatus by which a plurality of points are simultaneously measured by selecting and changing over an optical path even when only a single measuring channel of an optical measuring device exists. SOLUTION: The multipoint measuring apparatus is provided with a light source 1 and a light source 2; a plurality of projection fibers 5, 6 used to irradiate beams of light from the light sources at the plurality of points; a plurality of light receiving fibers 8, 9 used to collect beams of transmitted light, reflected light, scattered light and the like from the plurality of points; a beam selector 10 composed of a rotating disk 12 having one transmission hole used to pass the beams of light collected by the plurality of fibers 8, 9 to any one light receiving fiber; and an MCPD 4. Consequently, when the rotating disk 12 is turned and when the transmission hole is brought to, and made at a standstill in, a position passing the beams of light in a channel to be measured, the beams of light in the light receiving fiber are transmitted and measured. When the beams of light in other channels are measured, the rotating disk is turned by a prescribed angle. COPYRIGHT: (C)2004,JPO

    Abstract translation: 要解决的问题:提供一种多点测量装置,即使当仅存在光学测量装置的单个测量通道时,通过选择和切换光路来同时测量多个点。 解决方案:多点测量装置设置有光源1和光源2; 多个用于在多个点处照射来自光源的光束的投影光纤5,6; 用于从多个点收集透射光,反射光,散射光等的光束的多个受光光纤8,9; 由具有一个传输孔的旋转盘12组成的光束选择器10,用于将由多个光纤8,9收集的光束传递到任何一个光接收光纤; 因此,当旋转盘12转动时,并且当传输孔被带到静止时,通过待测量通道中的光束的位置时,光束在 光接收光纤被传输和测量。 当测量其他通道中的光束时,旋转盘转动规定的角度。 版权所有(C)2004,JPO

    多點測定裝置及方法 MULTIPOINT MEASUREMENT SYSTEM AND METHOD
    10.
    发明专利
    多點測定裝置及方法 MULTIPOINT MEASUREMENT SYSTEM AND METHOD 失效
    多点测定设备及方法 MULTIPOINT MEASUREMENT SYSTEM AND METHOD

    公开(公告)号:TWI231363B

    公开(公告)日:2005-04-21

    申请号:TW092107081

    申请日:2003-03-28

    IPC: G01J

    Abstract: 本發明是一種多點測定裝置,具備有:光源1,2;多根之投光光纖5,6,用來將光源之光照射在試料之多個點;多根之受光光纖8,9,用來採集來自該多個點之透過光、反射光和散射光等;射束選擇器10,由具有1個透過孔之旋轉圓板12構成,用來使該多根之受光光纖8,9所採集到之光,通到任何1根之受光光纖;和MCPD4。當使旋轉圓板12旋轉,使之移動到可以讓欲測定之通道光通過透過孔後保持靜止的話,如此光便只透過該受光光纖而進行測定。要測定其他通道之光時,可以使旋轉圓板旋轉指定之角度。

    Abstract in simplified Chinese: 本发明是一种多点测定设备,具备有:光源1,2;多根之投光光纤5,6,用来将光源之光照射在试料之多个点;多根之受光光纤8,9,用来采集来自该多个点之透过光、反射光和散射光等;射束选择器10,由具有1个透过孔之旋转圆板12构成,用来使该多根之受光光纤8,9所采集到之光,通到任何1根之受光光纤;和MCPD4。当使旋转圆板12旋转,使之移动到可以让欲测定之信道光通过透过孔后保持静止的话,如此光便只透过该受光光纤而进行测定。要测定其他信道之光时,可以使旋转圆板旋转指定之角度。

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