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公开(公告)号：CN106338524A
公开(公告)日：2017-01-18
申请号：CN201610709591.9
申请日：2016-08-23
Applicant: 中国科学院自动化研究所
IPC: G01N21/95 , G01N21/958
CPC classification number: G01N21/95 , G01N21/958 , G01N2021/9511 , G01N2201/103 , G01N2201/108
Abstract: 本发明公开了一种竖直光学元件表面损伤的显微扫描成像采集装置和方法。该装置包括：二维扫描运动平台、一维调焦轴、自动变倍显微镜头、面阵彩色CCD、同轴光源、环形光源、色散共焦位移传感器、系统控制器、工控机、隔震平台和显示器。该装置能够自动采集、存储图像，能够自动完成图像拼接，具备图像分析能力，能够统计图像中损伤点的数量和尺度。本发明能够实现光路中竖直放置光学元件表面的在线快速高精度显微扫描成像采集和损伤检测，具有广泛的应用前景和可观的社会经济效益。
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2.发明授权System and method for self-referencing a sensor in a micron-sized deep flow chamber 失效用于在微米级深流动室中自我参考传感器的系统和方法公开(公告)号：US08021613B2
公开(公告)日：2011-09-20
申请号：US11900263
申请日：2007-09-11
Applicant: Norman H. Fontaine , Prantik Mazumder , Mark A. Quesada , Eric J. Mozdy , Po Ki Yuen
Inventor： Norman H. Fontaine , Prantik Mazumder , Mark A. Quesada , Eric J. Mozdy , Po Ki Yuen
CPC classification number: G01N21/7743 , G01N21/05 , G01N21/276 , G01N21/553 , G01N2021/0346 , G01N2021/058 , G01N2201/108 , G01N2201/1211 , G01N2201/1217 , G01N2201/127 , G01N2201/12723 , G01N2201/128 , Y10T436/117497 , Y10T436/2575
Abstract: A system and method are described herein for self-referencing a sensor that is used to detect a biomolecular binding event and/or kinetics which occur in a sample solution flowing along side a reference solution in a micron-sized deep flow channel.
Abstract translation: 本文描述了一种系统和方法，用于自我参考用于检测在微米尺寸深流动通道中沿着参考溶液侧流动的样品溶液中发生的生物分子结合事件和/或动力学的传感器。
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3.发明申请System and method for self-referencing a sensor in a micron-sized deep flow chamber 失效用于在微米级深流动室中自我参考传感器的系统和方法公开(公告)号：US20060106557A1
公开(公告)日：2006-05-18
申请号：US10993565
申请日：2004-11-18
Applicant: Norman Fontaine , Prantik Mazumder , Mark Quesada , Eric Mozdy , Po Yuen
Inventor： Norman Fontaine , Prantik Mazumder , Mark Quesada , Eric Mozdy , Po Yuen
IPC: G01R35/00
CPC classification number: G01N21/7743 , G01N21/05 , G01N21/276 , G01N21/553 , G01N2021/0346 , G01N2021/058 , G01N2201/108 , G01N2201/1211 , G01N2201/1217 , G01N2201/127 , G01N2201/12723 , G01N2201/128 , Y10T436/117497 , Y10T436/2575
Abstract: A system and method are described herein for self-referencing a sensor that is used to detect a biomolecular binding event and/or kinetics which occur in a sample solution flowing along side a reference solution in a micron-sized deep flow channel.
Abstract translation: 本文描述了一种系统和方法，用于自我参考用于检测在微米尺寸深流动通道中沿着参考溶液侧流动的样品溶液中发生的生物分子结合事件和/或动力学的传感器。
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公开(公告)号：US20110305598A1
公开(公告)日：2011-12-15
申请号：US13213744
申请日：2011-08-19
Applicant: Norman H. Fontaine , Prantik Mazumder , Mark A. Quesada , Eric J. Mozdy , Po Ki Yuen
Inventor： Norman H. Fontaine , Prantik Mazumder , Mark A. Quesada , Eric J. Mozdy , Po Ki Yuen
IPC: G01N33/48
CPC classification number: G01N21/7743 , G01N21/05 , G01N21/276 , G01N21/553 , G01N2021/0346 , G01N2021/058 , G01N2201/108 , G01N2201/1211 , G01N2201/1217 , G01N2201/127 , G01N2201/12723 , G01N2201/128 , Y10T436/117497 , Y10T436/2575
Abstract: A microfluidic device is described herein which comprises a micron-sized deep flow channel and a sensor. The micron-sized deep flow channel is configured such that a sample solution and a reference solution flow side-by-side to one another in a single sensing region of the sensor. The single sensing region is divided into a detection region and a reference region which are contiguous to one another and which are respectively interfaced with the sample solution and the reference solution that flow side-by-side to one another in a longitudinal direction within the micron-sized deep flow channel.
Abstract translation: 本文描述了一种微流体装置，其包括微米级的深流动通道和传感器。 微米尺寸深流通道被配置为使得样品溶液和参比溶液在传感器的单个感测区域中彼此并排流动。 单个感测区域被分成彼此邻接的检测区域和参考区域，它们分别与样品溶液和在微米内沿纵向彼此并排流动的参比溶液接合。 深流道。
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5.发明申请System and method for self-referencing a sensor in a micron-sized deep flow chamber 失效用于在微米级深流动室中自我参考传感器的系统和方法公开(公告)号：US20080063569A1
公开(公告)日：2008-03-13
申请号：US11900263
申请日：2007-09-11
Applicant: Norman Fontaine , Prantik Mazumder , Mark Quesada , Eric Mozdy , Po Yuen
Inventor： Norman Fontaine , Prantik Mazumder , Mark Quesada , Eric Mozdy , Po Yuen
IPC: G01N21/01
CPC classification number: G01N21/7743 , G01N21/05 , G01N21/276 , G01N21/553 , G01N2021/0346 , G01N2021/058 , G01N2201/108 , G01N2201/1211 , G01N2201/1217 , G01N2201/127 , G01N2201/12723 , G01N2201/128 , Y10T436/117497 , Y10T436/2575
Abstract: A system and method are described herein for self-referencing a sensor that is used to detect a biomolecular binding event and/or kinetics which occur in a sample solution flowing along side a reference solution in a micron-sized deep flow channel.
Abstract translation: 本文描述了一种系统和方法，用于自我参考用于检测在微米尺寸深流动通道中沿着参考溶液侧流动的样品溶液中发生的生物分子结合事件和/或动力学的传感器。
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Patent Agency Ranking
6.发明授权System and method for self-referencing a sensor in a micron-sized deep flow chamber 失效用于在微米级深流动室中自我参考传感器的系统和方法公开(公告)号：US07285420B2
公开(公告)日：2007-10-23
申请号：US10993565
申请日：2004-11-18
Applicant: Norman H. Fontaine , Prantik Mazumder , Mark A. Quesada , Eric J. Mozdy , Po Ki Yuen
Inventor： Norman H. Fontaine , Prantik Mazumder , Mark A. Quesada , Eric J. Mozdy , Po Ki Yuen
CPC classification number: G01N21/7743 , G01N21/05 , G01N21/276 , G01N21/553 , G01N2021/0346 , G01N2021/058 , G01N2201/108 , G01N2201/1211 , G01N2201/1217 , G01N2201/127 , G01N2201/12723 , G01N2201/128 , Y10T436/117497 , Y10T436/2575
Abstract: A system and method are described herein for self-referencing a sensor that is used to detect a biomolecular binding event and/or kinetics which occur in a sample solution flowing along side a reference solution in a micron-sized deep flow channel.
Abstract translation: 本文描述了一种系统和方法，用于自我参考用于检测在微米尺寸深流动通道中沿着参考溶液侧流动的样品溶液中发生的生物分子结合事件和/或动力学的传感器。
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7.发明公开SYSTEM AND METHOD FOR SELF-REFERENCING A SENSOR IN A MICRON-SIZED DEEP FLOW CHAMBER 审中-公开系统和方法自引用在深流室中的传感器的微小直径
公开(公告)号：EP1812786A1
公开(公告)日：2007-08-01
申请号：EP05819802.9
申请日：2005-11-09
Applicant: Corning Incorporated
Inventor： MOZDY, Eric J , YUEN, Po Ki , FONTAINE, Norman H , MAZUMDER, Prantik , QUESADA, Mark A
CPC classification number: G01N21/7743 , G01N21/05 , G01N21/276 , G01N21/553 , G01N2021/0346 , G01N2021/058 , G01N2201/108 , G01N2201/1211 , G01N2201/1217 , G01N2201/127 , G01N2201/12723 , G01N2201/128 , Y10T436/117497 , Y10T436/2575
Abstract: A system and method are described herein for self-referencing a sensor that is used to detect a biomolecular binding event and/or kinetics which occur in a sample solution flowing along side a reference solution in a micron-sized deep flow channel.
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8.发明申请SYSTEM AND METHOD FOR SELF-REFERENCING A SENSOR IN A MICRON-SIZED DEEP FLOW CHAMBER 审中-公开自动深孔深度传感器自动调节系统及方法
公开(公告)号：WO2006055401A1
公开(公告)日：2006-05-26
申请号：PCT/US2005/040845
申请日：2005-11-09
Applicant: CORNING INCORPORATED , MOZDY, Eric J , YUEN, Po Ki , FONTAINE, Norman H , MAZUMDER, Prantik , QUESADA, Mark A
Inventor： MOZDY, Eric J , YUEN, Po Ki , FONTAINE, Norman H , MAZUMDER, Prantik , QUESADA, Mark A
CPC classification number: G01N21/7743 , G01N21/05 , G01N21/276 , G01N21/553 , G01N2021/0346 , G01N2021/058 , G01N2201/108 , G01N2201/1211 , G01N2201/1217 , G01N2201/127 , G01N2201/12723 , G01N2201/128 , Y10T436/117497 , Y10T436/2575
Abstract: A system and method are described herein for self-referencing a sensor that is used to detect a biomolecular binding event and/or kinetics which occur in a sample solution flowing along side a reference solution in a micron-sized deep flow channel.
Abstract translation: 本文描述了一种系统和方法，用于自我参考用于检测在微米尺寸深流动通道中沿着参考溶液侧流动的样品溶液中发生的生物分子结合事件和/或动力学的传感器。
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公开(公告)号：JP4866364B2
公开(公告)日：2012-02-01
申请号：JP2007543132
申请日：2005-11-09
Applicant: コーニング インコーポレイテッド
Inventor： エイ ケサダ，マーク , エイチ フォンテイン，ノーマン , マズムデル，プランティク , ジェイ モズディー，エリック , キ ユエン，ポー
IPC: G01N21/27 , G01N33/543
CPC classification number: G01N21/7743 , G01N21/05 , G01N21/276 , G01N21/553 , G01N2021/0346 , G01N2021/058 , G01N2201/108 , G01N2201/1211 , G01N2201/1217 , G01N2201/127 , G01N2201/12723 , G01N2201/128 , Y10T436/117497 , Y10T436/2575
Abstract: A system and method are described herein for self-referencing a sensor that is used to detect a biomolecular binding event and/or kinetics which occur in a sample solution flowing along side a reference solution in a micron-sized deep flow channel.
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公开(公告)号：JP2008521005A
公开(公告)日：2008-06-19
申请号：JP2007543132
申请日：2005-11-09
Applicant: コーニング インコーポレイテッド
Inventor： エイ ケサダ，マーク , エイチ フォンテイン，ノーマン , マズムデル，プランティク , ジェイ モズディー，エリック , キ ユエン，ポー
IPC: G01N21/27 , G01N33/543 , G01N37/00
CPC classification number: G01N21/7743 , G01N21/05 , G01N21/276 , G01N21/553 , G01N2021/0346 , G01N2021/058 , G01N2201/108 , G01N2201/1211 , G01N2201/1217 , G01N2201/127 , G01N2201/12723 , G01N2201/128 , Y10T436/117497 , Y10T436/2575
Abstract: A system and method are described herein for self-referencing a sensor that is used to detect a biomolecular binding event and/or kinetics which occur in a sample solution flowing along side a reference solution in a micron-sized deep flow channel.
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