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    SCALING AND PARAMETERIZING A CONTROLLER
    91.
    发明申请
    SCALING AND PARAMETERIZING A CONTROLLER 有权
    扩展和参数控制器

    公开(公告)号：US20140107813A1

    公开(公告)日：2014-04-17

    申请号：US14042983

    申请日：2013-10-01

    Applicant: Cleveland State University

    Inventor： Zhiqiang Gao

    IPC: G05B13/04

    CPC classification number: G05B13/024 ,  G05B5/01 ,  G05B11/42 ,  G05B13/042 ,  G05B15/02 ,  G05B19/416 ,  G05B2219/33347

    Abstract: Controller scaling and parameterization are described. Techniques that can be improved by employing the scaling and parameterization include, but are not limited to, controller design, tuning and optimization. The scaling and parameterization methods described here apply to transfer function based controllers, including PID controllers. The parameterization methods also applies to state feedback and state observer based controllers, as well as linear active disturbance rejection controllers. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the application. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.

    Abstract translation: 描述控制器缩放和参数化。 可以通过使用缩放和参数化来改进的技术包括但不限于控制器设计，调整和优化。 这里描述的缩放和参数化方法适用于基于传递函数的控制器，包括PID控制器。 参数化方法也适用于状态反馈和基于状态观察器的控制器，以及线性有源扰动抑制控制器。 要强调的是，该摘要被提供以符合要求抽象的规则，允许搜索者或其他读者快速确定申请的主题。 提交它的理解是，它不会用于解释或限制权利要求的范围或含义。

    AMIDE DERIVATIVES OF BENZENE-SULFONANILIDE, PHARMACEUTICAL COMPOSITION THEREOF AND METHOD FOR CANCER TREATMENT USING THE SAME
    95.
    发明公开
    AMIDE DERIVATIVES OF BENZENE-SULFONANILIDE, PHARMACEUTICAL COMPOSITION THEREOF AND METHOD FOR CANCER TREATMENT USING THE SAME 审中-公开
    阿米德衍生物FROM BENZENSULFONANILID，其药物组合物和方法用于癌症的治疗，

    公开(公告)号：EP2629767A1

    公开(公告)日：2013-08-28

    申请号：EP11834950.5

    申请日：2011-10-18

    Applicant: Cleveland State University

    Inventor： SU, Bin ,  ZHOU, Aimin ,  XU, Yan

    IPC: A61K31/18 ,  A61K31/165

    CPC classification number: C07C311/08 ,  C07C2601/08 ,  C07D261/18 ,  C07D307/68 ,  C07D317/60 ,  C07D333/38

    Abstract: The invention provides a compound of formula (I), a pharmaceutical composition thereof, a method of preparing a medicament for the treatment of a cancer, and a method of treating cancers. The invention exhibits merits against cancers such as significantly higher potency and effectiveness over a broader range of cancers. In formula (I), Ra is a benzyl group with alkyl and/or alkoxy; Rb is selected from H and alkyl groups; Rf is an alkyl; and R3 is selected from a substituted phenyl, a heterocyclic group, and wherein Rc is selected from a fused ring, fused rings, and any bivalent cyclic group.

    Abstract translation: 本发明提供式（I）的化合物，其药物组合物，制备药物用于治疗癌症，以及治疗癌症的方法的方法。 本发明表现出对癌症的优点：如显着更高的效力和有效性在更宽范围的癌症。 在式（I）中，Ra是具有烷基和/或烷苄基; R b选自H和烷基; R f是一个烷基; 且R 3选自取代的苯基，杂环基，和R c是从worin稠环，稠环，和任何二价环状基团。

    Controllers, observer, and applications thereof
    96.
    发明公开
    Controllers, observer, and applications thereof 审中-公开
    Steuerungen，Beobachter和Anwendungendafür

    公开(公告)号：EP2447792A1

    公开(公告)日：2012-05-02

    申请号：EP11009615.3

    申请日：2006-09-18

    Applicant: Cleveland State University

    Inventor： Gao, Zhiqiang ,  Miklosovic, Robert ,  Radke, Aaron ,  Zhou, Wankun ,  Zheng, Qing

    IPC: G05B13/04 ,  G05B23/02

    CPC classification number: G05B13/04 ,  F05B2260/80 ,  G05B2219/25298

    Abstract: Controller scaling and parameterization are described. Techniques that can be improved by employing the scaling and parameterization include, but are not limited to, controller design, tuning and optimization, and fault detection and isolation. The scaling and parameterization methods described here apply to transfer function based controllers, including PID controllers. The parameterization methods also apply to state feedback and state observer based controllers, as well as linear active disturbance rejection (ADRC) controllers. Parameterization simplifies the use of ADRC. A discrete extended state observer (DESO) and a generalized extended state observer (GESO) are described. They improve the performance of the ESO and therefore ADRC. A tracking control algorithm is also described that improves the performance of the ADRC controller. A general algorithm is described for applying ADRC to multi-input multi-output systems. Several specific applications of the control systems and processes are disclosed, such as web tensioning control systems and jet engine control.

    Abstract translation: 描述控制器缩放和参数化。 可以通过使用缩放和参数化来改进的技术包括但不限于控制器设计，调整和优化以及故障检测和隔离。 这里描述的缩放和参数化方法适用于基于传递函数的控制器，包括PID控制器。 参数化方法也适用于状态反馈和基于状态观察器的控制器，以及线性有源扰动抑制（ADRC）控制器。 参数化简化了ADRC的使用。 描述了离散扩展状态观察器（DESO）和广义扩展状态观察器（GESO）。 它们提高了ESO和ADRC的性能。 还描述了改善ADRC控制器的性能的跟踪控制算法。 描述了将ADRC应用于多输入多输出系统的一般算法。 公开了控制系统和过程的几个具体应用，例如卷筒纸张紧控制系统和喷气发动机控制。

    AGGLOMERATED PARTICLES FOR AEROSOL DRUG DELIVERY
    98.
    发明公开
    AGGLOMERATED PARTICLES FOR AEROSOL DRUG DELIVERY 审中-公开
    活性颗粒为产品的气溶胶形式供应

    公开(公告)号：EP1480691A2

    公开(公告)日：2004-12-01

    申请号：EP03713926.8

    申请日：2003-03-05

    Applicant: CLEVELAND STATE UNIVERSITY

    Inventor： ANNAPRAGADA, Annanth ,  BHAVANE, Rohan

    IPC: A61M1/00

    CPC classification number: A61K9/0078 ,  A61K9/1271 ,  A61K47/6911 ,  A61K47/6941

    Abstract: The invention provides a drug delivery vehicle for inhalation by a patient. The drug delivery vehicle comprises biocompatible particles between 0.1 and 1.0 microns in diameter, that are loaded with one or more drugs and which are crosslinked together to form agglomerates. The agglomerates can also provide for delivery of contrast-enhancing agents for clinical imaging. The invention also provides methods of making the inventive agglomerates, pharmaceutical compositions comprising the agglomerates, and methods for delivering drugs or contrast-enhancing agents to a patient by inhalation of pharmaceutical compositions containing the agglomerates.

    ACTUATING DEVICE FOR POWERED ORTHOSIS
    99.
    发明公开
    ACTUATING DEVICE FOR POWERED ORTHOSIS 审中-公开

    公开(公告)号：EP3848012A1

    公开(公告)日：2021-07-14

    申请号：EP21158642.5

    申请日：2018-04-12

    Applicant: Cleveland State University

    Inventor： Sawicki, Jerzy T. ,  Laubscher, Curt A. ,  Farris, Ryan J. ,  Etheridge, Steven J-S

    IPC: A61H1/02 ,  A61H3/00 ,  F16H7/08 ,  F16H7/02

    Abstract: An actuating device for orthosis including a housing, a motor, a transmission disposed in the housing, and an actuating arm. The transmission is operatively connected to the motor such that the motor provides power to the transmission. The transmission includes a first stage, a second stage, and a third stage. The first stage has a first sprocket, a second sprocket, and a first drive belt tensioned between the first sprocket and the second sprocket. The first sprocket is attached to a shaft of the motor. The second stage has a third sprocket, a fourth sprocket, and a second drive belt tensioned by the third sprocket and the fourth sprocket. The third sprocket is attached to the second sprocket of the first stage. The third stage has a fifth sprocket, a sixth sprocket, and a third drive belt tensioned by the fifth sprocket and the sixth sprocket. The fifth sprocket is attached to the fourth sprocket of the second stage. The transmission additionally includes a first shaft and a second shaft. The second sprocket, the third sprocket, and the sixth sprocket are attached to the first shaft, and the fourth sprocket and the fifth sprocket are attached to the second shaft. The actuating arm is operatively connected to the sixth sprocket of the third stage of the transmission such that the power provided to the transmission by the motor causes the actuating arm to provide an output torque.

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