公开(公告)号：US09878321B2

公开(公告)日：2018-01-30

申请号：US15094930

申请日：2016-04-08

Applicant: INVISTA North America S.a.r.l.

Inventor： Mariusz Kamionka ,  Alex Conradie

IPC: C07C209/86 ,  B01J47/04 ,  C01F1/00 ,  B01J47/00 ,  C02F1/42 ,  B01J39/18 ,  B01J47/014 ,  B01J47/11 ,  B01J49/05 ,  C02F1/20 ,  C02F101/34 ,  C02F101/38

CPC classification number: B01J49/05 ,  B01J39/18 ,  B01J47/014 ,  B01J47/11 ,  C02F1/20 ,  C02F1/42 ,  C02F2101/34 ,  C02F2101/38 ,  C02F2303/16 ,  C07C209/86

Abstract: Described herein are processes and apparatus for the high purity and high concentration recovery of multivalent products via continuous ion exchange from aqueous solutions for further down-stream purification.

公开(公告)号：US20180023088A1

公开(公告)日：2018-01-25

申请号：US15659521

申请日：2017-07-25

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Alex VAN ECK CONRADIE ,  Achuthanunni CHOKKATHUKALAM ,  Remi Ako Mbianyor MOMO

IPC: C12N15/52 ,  C08G69/08 ,  C12N9/16 ,  C12P13/00 ,  C12N9/04 ,  C12N9/00

CPC classification number: C12N15/52 ,  C08G69/08 ,  C12N9/0006 ,  C12N9/16 ,  C12N9/93 ,  C12P7/18 ,  C12P7/40 ,  C12P7/42 ,  C12P7/44 ,  C12P13/00 ,  C12P13/005 ,  C12Y101/01001 ,  C12Y101/01284 ,  C12Y301/02012 ,  C12Y603/04003

Abstract: This disclosure describes methods for regulating the biosynthesis of pimelic acid, 7-aminoheptanoate, 7-hydroxyheptanoate, heptamethylenediamine, 7-aminoheptanol, or 1,7-heptanediol by channeling increased flux through the biosynthesis pathway to obtain an intermediate required for growth of the host microorganism.

公开(公告)号：US20170349535A1

公开(公告)日：2017-12-07

申请号：US15491018

申请日：2017-04-19

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： Alex Conradie

IPC: C07C227/40 ,  C07C67/58 ,  C07C51/47 ,  B01D15/18 ,  B01D15/36 ,  B01D15/20 ,  C07C229/06 ,  C07C53/126

CPC classification number: B01D15/362 ,  B01D15/1892 ,  B01D15/20 ,  B01D15/361 ,  C07C51/47 ,  C07C53/126 ,  C07C67/58 ,  C07C227/40 ,  C07C229/06

Abstract: This document describes a process for the high purity and high concentration recovery of monovalent products via continuous ion exchange from aqueous solution for further down-stream purification.

公开(公告)号：US20170240936A1

公开(公告)日：2017-08-24

申请号：US15436315

申请日：2017-02-17

Applicant: INVISTA North America S.a.r.l.

Inventor： Gary SMITH ,  Alex Van Eck CONRADIE ,  Gregory S. KIRBY ,  Paul S. PEARLMAN

IPC: C12P13/00 ,  C12P7/62 ,  C25B1/04 ,  C12M1/00 ,  C12M1/34 ,  C12P5/00 ,  C12P7/06 ,  C12N1/20

CPC classification number: C12P13/001 ,  C12M29/00 ,  C12M41/00 ,  C12N1/20 ,  C12P5/00 ,  C12P5/007 ,  C12P5/02 ,  C12P7/065 ,  C12P7/24 ,  C12P7/625 ,  C12P13/00 ,  C25B1/04 ,  F01D15/10 ,  F01K7/16 ,  F01K11/02 ,  F05D2220/31 ,  Y02E50/17 ,  Y02E50/343 ,  Y02E60/366

Abstract: The present disclosure describes biocatalytic processes for producing a product, comprising providing an aqueous stream (AS) comprising at least one fermentable substrate and a gaseous stream (GS) comprising at least one of CO2/H2, H2, methane, and/or CO to a fermentation zone, wherein the GS and AS stream are optionally contacted and/or mixed; the fermentation zone comprising at least one organism capable of metabolizing an AS substrate and a GS substrate, wherein the fermentation operates at conditions to mixotrophically metabolize at least one gaseous substrate in the GS and at least one substrate in the AS, producing the product. The present disclosure also describes compositions comprising an AS, a GS, and an organism, wherein the organism or an equivalent or engineered equivalent thereof is a methanotroph or a hydrogen-metabolizing or CO-metabolizing chemolithotrophic organism, and wherein the organism is capable of mixotrophic metabolism of at least one gaseous substrate in the GS and at least one substrate in the AS. The present disclosure also describes a process wherein said fermentation operates at conditions to mixotrophically metabolize at least H2 in the gaseous stream and glycerol and lactic acid in the aqueous stream. The present disclosure also describes a system for producing a fermentation or bio-derived product.

公开(公告)号：US20170159092A1

公开(公告)日：2017-06-08

申请号：US15368092

申请日：2016-12-02

Applicant: INVISTA North America S.a.r.l.

Inventor： Alexander Van Eck CONRADIE ,  Adriana Leonora BOTES ,  Jonathan KENNEDY ,  Nadia Fatma KADI

IPC: C12P19/32 ,  C12N9/02 ,  C08G69/02 ,  C12P7/48 ,  C12P7/42 ,  C12P7/18 ,  C12N9/10 ,  C12P13/00

CPC classification number: C12P19/32 ,  C08G69/02 ,  C12N9/0008 ,  C12N9/1029 ,  C12N9/1096 ,  C12N9/13 ,  C12P7/18 ,  C12P7/42 ,  C12P7/48 ,  C12P11/00 ,  C12P13/00 ,  C12P13/001 ,  C12P21/00 ,  C12Y102/99006 ,  C12Y203/01 ,  C12Y203/01016 ,  C12Y203/01041 ,  C12Y203/01174 ,  C12Y203/01179 ,  C12Y203/0118 ,  C12Y206/01018 ,  C12Y208/03

Abstract: This document describes biochemical pathways for producing 7-aminoheptanoic acid using a β-ketoacyl synthase or a β-ketothiolase to form an N-acetyl-5-amino-3-oxopentanoyl-CoA intermediate. 7-aminoheptanoic acid can be enzymatically converted to pimelic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol or corresponding salts thereof. This document also describes recombinant microorganisms producing 7-aminoheptanoic acid as well as pimelic acid, 7-hydroxyheptanoic acid, heptamethylenediamine and 1,7-heptanediol or corresponding salts thereof.

公开(公告)号：US20160297746A1

公开(公告)日：2016-10-13

申请号：US15094770

申请日：2016-04-08

Applicant: INVISTA NORTH AMERICA S.a.r.l.

Inventor： Gary Smith ,  Gregory S Kirby ,  Paul Pearlman

IPC: C07C227/40 ,  C07C213/10 ,  C07C209/86

CPC classification number: B01D15/185 ,  B01D15/1892 ,  C07C209/82 ,  C07C209/86 ,  C07C211/09 ,  C07C213/10 ,  C07C227/38 ,  C07C227/40 ,  C12P13/001 ,  C12P13/005 ,  C07C211/12 ,  C07C229/08

Abstract: The present disclosure relates to methods for separating at least one amine chosen from diamines and omega-aminoacids from a feed mixture using a simulated moving bed (SMB) adsorptive technology.

Abstract translation: 本公开涉及使用模拟移动床（SMB）吸附技术从进料混合物中分离选自二胺和ω-氨基酸的至少一种胺的方法。

公开(公告)号：US20160251645A1

公开(公告)日：2016-09-01

申请号：US15056026

申请日：2016-02-29

Applicant: INVISTA North America S.a.r.l.

Inventor： ADRIANA L. BOTES ,  Nadia Kadi ,  Mihai Luchian Azoitei ,  Yih-En A. Ban ,  Daniela Grabs-Röthlisberger ,  Alexander Pisarchik ,  Alexandre Zanghellini ,  Eric Althoff

IPC: C12N9/88 ,  C07K16/40 ,  G01N33/573 ,  C12P5/00 ,  C08F36/06 ,  C07C11/18 ,  C07C11/21 ,  C08F36/08 ,  C08F36/22 ,  C12P5/02 ,  C07C11/167

Abstract: The present disclosure provides novel polypeptides with 3-buten-2-ol dehydratase activity, polypeptides with catalytic activity in the conversion of 3-methyl-3-buten-2-ol to isoprene, and crystal structure data for one of such polypeptides. Methods of making and using the polypeptides and their related crystal structure data are also provided.

公开(公告)号：US09220742B1

公开(公告)日：2015-12-29

申请号：US14800961

申请日：2015-07-16

Applicant: INVISTA North America S.a.r.l.

Inventor： Adriana Botes ,  Nadia Kadi ,  Mihai Luchian Azoitei ,  Yih-En A Ban ,  Daniela Grabs-Röthlisberger ,  Alexander Pisarchik ,  Alexandre Zanghellini ,  Eric Althoff

IPC: A61K38/51 ,  C12N9/90 ,  A61K38/00

CPC classification number: C12N9/88 ,  A61K38/00 ,  C07C11/167 ,  C07C11/18 ,  C07C11/21 ,  C07K16/40 ,  C07K2299/00 ,  C08F36/06 ,  C08F36/08 ,  C08F36/22 ,  C08F136/06 ,  C08F136/08 ,  C12P5/007 ,  C12P5/026 ,  C12Y402/01053 ,  C12Y402/01095 ,  C12Y402/01127 ,  C12Y402/01131 ,  G01N33/573

Abstract: The present disclosure provides novel polypeptides with 3-buten-2-ol dehydratase activity, polypeptides with catalytic activity in the conversion of 3-methyl-3-buten-2-ol to isoprene, and crystal structure data for one of such polypeptides. Methods of making and using the polypeptides and their related crystal structure data are also provided.

Abstract translation: 本公开提供具有3-丁烯-2-醇脱水酶活性的新型多肽，在3-甲基-3-丁烯-2-醇转化为异戊二烯时具有催化活性的多肽，以及这些多肽之一的晶体结构数据。 还提供了制备和使用多肽及其相关晶体结构数据的方法。

公开(公告)号：US20150360965A1

公开(公告)日：2015-12-17

申请号：US14741978

申请日：2013-12-12

Applicant: INVISTA TECHNOLOGIES S.A.R.L. ,  INVISTA NORTH AMERICA S.A.R.L.

Inventor： Stewart FORSYTH ,  Aiguo LIU ,  Martin J. RENNER ,  Brent J. STAHLMAN

IPC: C01C3/02 ,  B01D53/26

CPC classification number: C01C3/0212 ,  B01D53/26 ,  C01C3/022

Abstract: The system and methods described herein solve problems of inaccurate flow control, loss of optimum reactant gas feed ratios, and the associated inefficiencies brought on by variable humidity in reactant feedstream gases during production of hydrogen cyanide by an Andrussow process.

Abstract translation: 本文所述的系统和方法解决了通过安德鲁斯（Andrussow）工艺生产氰化氢期间反应物进料流气体中由不可变湿度引起的流量控制不正确，最佳反应气体进料比的损失以及相关的无效率问题。

公开(公告)号：US20150217877A1

公开(公告)日：2015-08-06

申请号：US14420972

申请日：2013-08-13

Applicant: INVISTA NORTH AMERICA S.A.R.L.

Inventor： David W. Schumann

IPC: B65B1/08 ,  B65B1/22 ,  B65B1/24 ,  B65B1/16

CPC classification number: B65B1/08 ,  B65B1/16 ,  B65B1/22 ,  B65B1/24 ,  B65H54/84 ,  B65H2701/31

Abstract: Included are apparatus and methods for preparing a yarn package for a small portion of yarn that provides substantially uniform tension on removal. The method includes providing an amount of yarn up to two pounds which is introduced to a small package with vacuum applied at the bottom of the container and vibration to assist yarn uniform packing of the yarn.

Abstract translation: 包括用于制备用于小部分纱线的纱线卷装的设备和方法，其在移除时提供基本均匀的张力。 该方法包括提供高达2磅的纱线，其被引入到小包装件中，真空施加在容器的底部并进行振动以辅助纱线的纱线均匀包装。