公开(公告)号：WO2015030580A1

公开(公告)日：2015-03-05

申请号：PCT/NL2014/050575

申请日：2014-08-26

Applicant: STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK

Inventor： LE NÔTRE, Jérôme Emile Lucien ,  SCOTT, Elinor Lindsey ,  CROES, Roeland Leo ,  VAN HAVEREN, Jacobus

IPC: C07C51/38 ,  C07C57/04 ,  C12P7/46 ,  C12P7/48

CPC classification number: C07C51/38 ,  C07C57/04

Abstract: Disclosed is a method of making methacrylic acid, or a carboxylic derivative thereof, from itaconic acid, isomers, or precursors thereof. A starting material comprising an acid selected from the group consisting of itaconic acid, citraconic acid, mesaconic acid, citric acid, aconitic acid, isocitric acid and mixtures thereof, is subjected to contact with 0.1 eq. to 3.0 eq. of a base, at a temperature of 150°C to 350°C, under the influence of a transition metal-containing heterogeneous catalyst. A better yield at lower temperatures is achieved.

Abstract translation: 公开了从衣康酸，异构体或其前体制备甲基丙烯酸或其羧酸衍生物的方法。 包含选自衣康酸，柠康酸，中康酸，柠檬酸，乌头酸，异柠檬酸及其混合物的酸的原料与0.1eq接触。 至3.0当量 的碱，在150℃至350℃的温度下，在含过渡金属的非均相催化剂的影响下。 在较低温度下获得更好的产率。

公开(公告)号：WO2014193230A1

公开(公告)日：2014-12-04

申请号：PCT/NL2014/050341

申请日：2014-05-28

Applicant: STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK

Inventor： FOEKEMA, Edwin Matheus

IPC: C02F1/66 ,  C02F103/02

CPC classification number: C02F1/66 ,  C02F2103/023 ,  C02F2103/08 ,  C02F2303/20

Abstract: The invention relates to environmentally friendly methods of reducing and/or preventing fouling on a surface of a component that is in contact with water. The invention further relates to a cooling system that is suited for employing the methods of the invention, and to a power plant, comprising such cooling system.

Abstract translation: 本发明涉及在与水接触的组分的表面上减少和/或防止结垢的环境友好的方法。 本发明还涉及适于采用本发明的方法的冷却系统以及包括这种冷却系统的发电厂。

公开(公告)号：WO2014083383A1

公开(公告)日：2014-06-05

申请号：PCT/IB2012/056789

申请日：2012-11-28

Applicant: STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK ,  FIERS, Martijn ,  BOUTILIER, Kimberly

Inventor： FIERS, Martijn ,  BOUTILIER, Kimberly

IPC: C07D401/04 ,  A01H4/00 ,  A01N43/40 ,  A01N43/42 ,  A01P21/00 ,  C07D215/54 ,  C12N5/04

CPC classification number: A01N43/42 ,  A01H4/001 ,  A01N43/38 ,  A01N43/40 ,  C07D215/54 ,  C07D401/04

Abstract: Cyclopentyl 2,7,7-trimethyl-5-oxo-4-(4-pyridinyl)-1,4,5,6,7,8-hexahydro-3- quinolinecarboxylate and similar compounds are potentiators of auxin-induced somatic embryogenesis in plants. In particular, the inventors have discovered certain of these compounds induce somatic embryogenesis in Arabidopsis in the presence of 2,4-D. Also tested is BAY K 8644. Methods of inducing somatic embryogenesis comprise exposing selected plant tissues, e.g. seed embryos, to auxins, e.g. 2.4-D and the compounds.

Abstract translation: 环戊基2,7,7-三甲基-5-氧代-4-（4-吡啶基）-1,4,5,6,7,8-六氢-3-喹啉羧酸酯和类似化合物是生长素诱导的体细胞胚发生的增强剂 植物。 特别地，本发明人发现这些化合物中的某些化合物在2,4-D存在下诱导拟南芥中的体细胞胚发生。 还测试了BAY K 8644.诱导体细胞胚发生的方法包括将所选择的植物组织，例如， 种子胚，到生长素，例如 2.4-D和化合物。

公开(公告)号：WO2013180565A1

公开(公告)日：2013-12-05

申请号：PCT/NL2013/050385

申请日：2013-05-28

Applicant: STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK

Inventor： GOSSELINK, Richard Johannes Antonius ,  VAN DAM, Jan Evert Gerard ,  TEUNISSEN, Wouter

IPC: A01N61/02 ,  A01N43/08 ,  B27K3/50 ,  A01P3/00

CPC classification number: B27K3/50 ,  A01N61/00 ,  B27K3/15 ,  B27K3/48 ,  B27K5/001 ,  B27K2240/70 ,  Y10T428/662 ,  A01N25/00 ,  A01N25/10 ,  A01N2300/00

Abstract: The invention relates to a lignocellulose preservative composition comprising in the range of from 50 to 98 wt% of a pyrolysis oil obtainable by pyrolysis of lignocellulosic material, a polymerisable furan compound and a catalyst for polymerising the furan compound in a catalytically effective amount. The invention further relates to a process for producing preserved lignocellulosic material comprising impregnating lignocellulosic material by immersion in such composition and subsequently curing the impregnated material and to preserved lignocellulosic material obtainable by such process and to an engineered wood or non- wood product comprising such lignocellulosic material.

Abstract translation: 本发明涉及一种木质纤维素防腐组合物，其包含50至98重量％的通过木质纤维素材料的热解可获得的热解油的范围，可聚合的呋喃化合物和用于使呋喃化合物以催化有效量聚合的催化剂。 本发明还涉及一种生产保藏的木质纤维素材料的方法，包括通过浸入该组合物中浸渍木质纤维素材料并随后固化浸渍的材料和通过这种方法获得的保存的木质纤维素材料和包含这种木质纤维素材料的工程木材或非木质产品 。

公开(公告)号：WO2013151428A1

公开(公告)日：2013-10-10

申请号：PCT/NL2013/050234

申请日：2013-03-28

Applicant: STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK

Inventor： VAN ES, Daniël Stephan ,  VAN HAVEREN, Jacobus ,  RAAIJMAKERS, Henricus Wilhelmus Carolina ,  VAN DER KLIS, Frits ,  VAN ENGELEN, Gerardus Petrus Franciscus Maria ,  FRISSEN, Augustinus Emmanuël

IPC: C07H1/00 ,  C07H7/033 ,  C07C51/235 ,  C07C59/285 ,  B01J23/52

CPC classification number: C07C51/235 ,  B01J21/04 ,  B01J21/063 ,  B01J23/52 ,  B01J23/66 ,  C07C59/285 ,  C07H1/00 ,  C07H7/033

Abstract: Disclosed is the oxidation of uronic acids, such as galacturonic acid, to the corresponding aldaric acids (characterized by the formula HOOC-(CHOH)n-COOH, with n being an integer of from 1 to 5) such as galactaric acids. The starting material comprising the uronic acid is subjected to oxygen under the influence of a supported gold catalyst and in the presence of a base. The oxidation occurs in good selectivity and yield, under unexpectedly mild conditions. A source of galacturonic acids is pectin, such as that derived from sugar beet pulp.

Abstract translation: 公开了将糖醛酸如半乳糖醛酸氧化成相应的阿拉德酸（其特征在于式HOOC-（CHOH）n-COOH，n为1至5的整数），如乳糖酸。 包含糖醛酸的起始材料在负载的金催化剂的影响下和在碱的存在下进行氧化。 在意想不到的温和条件下，氧化以良好的选择性和产率出现。 半乳糖醛酸的来源是果胶，例如衍生自甜菜糖浆的果胶。

公开(公告)号：WO2013141703A1

公开(公告)日：2013-09-26

申请号：PCT/NL2013/050202

申请日：2013-03-19

Applicant: STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK

Inventor： TIMMERMANS, Rian, Adriana, Hendrika ,  DE MORAES, Ricardo, Ermirio ,  MATSWIJK, Hendrikus, Cornelis ,  MATSER, Ariette, Margaretha

IPC: H05B3/60 ,  A23B5/01 ,  A23L3/005

CPC classification number: A23L2/48 ,  A23B5/01 ,  A23C3/02 ,  A23L3/005 ,  A23L3/01 ,  A23V2002/00 ,  H05B3/60

Abstract: The invention relates to an apparatus for fast and homogeneously heating a liquid product to a heating temperature by means of resistive heating, the apparatus comprising at least two vertically mounted, longitudinal, heating chambers that are arranged in series. The invention further relates to a process for fast and homogeneously heating a liquid product to a heating temperature by means of resistive heating in such apparatus comprising (a) continuously supplying the liquid product to the first heating chamber in series and flowing the liquid product continuously through the at least two heating chambers; (b) continuously generating an electrical current through the liquid product flowing through the heating chambers by continuously applying an electrical potential over each heating chamber, wherein the direction of the current is continuously alternated with a frequency of at least 500 Hz, to obtain heated liquid product; and (c) continuously discharging heated liquid product from the last heating chamber in series, wherein the liquid product has an electrical conductivity of at least 0.03 S/m.

Abstract translation: 本发明涉及一种用于通过电阻加热将液体产品快速均匀地加热到加热温度的装置，该装置包括串联布置的至少两个垂直安装的纵向加热室。 本发明还涉及通过这种设备中的电阻加热将液体产物快速均匀地加热至加热温度的方法，包括：（a）将液体产物串联连续供应到第一加热室，并将液体产物连续地流过 所述至少两个加热室; （b）通过在每个加热室上连续地施加电位，连续地通过流过加热室的液体产物产生电流，其中电流的方向以至少500Hz的频率连续地交替，以获得加热的液体 产品; 和（c）连续地从最后一个加热室排出加热的液体产物，其中液体产物具有至少0.03S / m的电导率。

公开(公告)号：WO2013125950A1

公开(公告)日：2013-08-29

申请号：PCT/NL2013/050105

申请日：2013-02-19

Applicant: STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK

Inventor： HAGBERG, Erik ,  MARTIN, Kevin ,  VAN EE, Jan ,  LE NÔTRE, Jérôme ,  VAN ES, Daniël Stephan ,  VAN HAVEREN, Jacobus

IPC: C07D493/04

CPC classification number: C07D493/04 ,  B01J23/42 ,  B01J23/44 ,  B01J23/462 ,  B01J23/464 ,  B01J23/52 ,  B01J23/755

Abstract: Disclosed is a process for the preparation of isoidide from isosorbide. An aqueous solution of isosorbide is subjected to epimerization in the presence of hydrogen under the influence of a catalyst comprising ruthenium on a support, preferably a carbon support. The process of the invention can be conducted using a relatively low hydrogen pressure, and leads to a desired distribution of epimers, favoring isoidide over isomannide and isosorbide.

Abstract translation: 公开了从异山梨醇制备异氰酸酯的方法。 在氢气存在下，在包含钌的催化剂在载体，优选碳载体上的影响下，使异山梨醇的水溶液进行差向异构化。 本发明的方法可以使用相对较低的氢气压力进行，并导致差向异构体的期望分布，有利于异麦芽酮糖苷和异山梨醇上的异氰酸酯。

公开(公告)号：WO2012150317A1

公开(公告)日：2012-11-08

申请号：PCT/EP2012/058194

申请日：2012-05-04

Applicant: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) ,  STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) ,  UNIVERSITÉ DE STRASBOURG ,  VERDELHO TRINDADE VAN, Gerven, Luisa Miguel ,  GRONEMEYER, Hinrich ,  PATTABHIRAMAN, Shankara Narayanan

Inventor： VERDELHO TRINDADE VAN, Gerven, Luisa Miguel ,  GRONEMEYER, Hinrich ,  PATTABHIRAMAN, Shankara Narayanan

IPC: C12Q1/68

CPC classification number: C12Q1/6806 ,  C12Q1/6865 ,  C12Q2522/101 ,  C12Q2525/143 ,  C12Q2535/122 ,  C12Q2521/131 ,  C12Q2525/173 ,  C12Q2531/101

Abstract: The present invention provides materials and methods for DNA amplification, in particular linear amplification methods using RNA polymerase. These methods permit high- throughput sequencing of pictogram amounts of DNA and are of use in a range of applications including genome-wide profiling of transcription factors and epigenetic DNA and histone modifications, global transcript profiling, mapping of chromatin conformations, as well as for forensic use and archaeological studies.

Abstract translation: 本发明提供用于DNA扩增的材料和方法，特别是使用RNA聚合酶的线性扩增方法。 这些方法允许图形量的DNA的高通量测序，并且在一系列应用中使用，包括转录因子和表观遗传学DNA的全基因组谱和组蛋白修饰，全局转录谱分析，染色质构象的映射以及法医学 使用和考古研究。

公开(公告)号：WO2012057617A2

公开(公告)日：2012-05-03

申请号：PCT/NL2011/050715

申请日：2011-10-18

Applicant: UNIVERSITEIT LEIDEN ,  STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK ,  VERPOORTE, Robert ,  LUBBE, Andrea ,  GUDE, Hendrikus

Inventor： VERPOORTE, Robert ,  LUBBE, Andrea ,  GUDE, Hendrikus

IPC: A01N43/16 ,  A01P15/00 ,  A01N43/08

CPC classification number: A01N43/16 ,  A01N65/42 ,  A01N25/00

Abstract: The present invention relates to a method for the production of sugars, in particular glycosides, from bulbs, comprising the steps of a) inducing gummosis in a bulb;b) optionally separating the gum from the bulb to obtain the gum;c) optionally extracting the sugar from the gum under polar or semipolar conditions.

Abstract translation: 本发明涉及一种从球茎生产糖类，特别是糖苷的方法，其包括以下步骤：a）在球茎中诱导胶化; b）任选地将球粒从球茎分离成 获得口香糖; c）任选地在极性或半极性条件下从口香糖中提取糖。

公开(公告)号：WO2012044168A1

公开(公告)日：2012-04-05

申请号：PCT/NL2011/050659

申请日：2011-09-29

Applicant: STICHTING DIENST LANDBOUWKUNDIG ONDERZOEK ,  VAN ES, Daniël Stephan ,  VAN DER KLIS, Frits ,  VAN HAVEREN, Jacobus

Inventor： VAN ES, Daniël Stephan ,  VAN DER KLIS, Frits ,  VAN HAVEREN, Jacobus

IPC: C07C51/27 ,  C07D307/60 ,  C07C55/10

CPC classification number: C07C51/27 ,  C07D307/60 ,  C07C55/06 ,  C07C55/10

Abstract: Disclosed is a method that allows obtaining succinic acid or succinic anhydride from biomass, with good yield, under mild conditions and yet avoiding fermentative processes. The method comprises obtaining levulinic acid from biomass, and converting the levulinic acid into succinic acid. According to the invention, the latter process is conducted by subjecting succinic acid to elevated temperature in the presence of nitric acid. Preferably vanadium pentoxide is added as a catalyst.

Abstract translation: 公开了一种能够在温和条件下从生物质获得琥珀酸或琥珀酸酐，而且能够以良好的产率获得并避免发酵过程的方法。 该方法包括从生物质获得乙酰丙酸，并将乙酰丙酸转化成琥珀酸。 根据本发明，后一种方法通过在硝酸存在下使琥珀酸升高而进行。 优选加入五氧化二钒作为催化剂。