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公开(公告)号：HU174323B
公开(公告)日：1979-12-28
申请号：HUHO001768
申请日：1975-02-12
Applicant: HOECHST AG
Inventor： BABEJ MILOS , BECK GERHARD , BARTMANN WILHELM , LERCH ULRICH
IPC: A61K31/557 , A61K31/5575 , A61P43/00 , C07C45/56 , C07C45/66 , C07C67/00 , C07C401/00 , C07C405/00 , C07D339/06 , C07C177/00
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公开(公告)号：AU4648079A
公开(公告)日：1979-11-22
申请号：AU4648079
申请日：1979-04-26
Applicant: HOECHST AG
Inventor： BARTMANN WILHELM , KONZ ELMAR , GEYER HARRY MAURICE
IPC: A61K31/47 , A61K31/472 , A61P25/08 , A61P25/24 , A61P25/26 , C07D217/22 , C07D401/04 , C07D403/04 , C07D409/14 , A61K31/495 , A61K31/535 , A61K31/54 , C07D401/12 , C07D401/14 , C07D413/12 , C07D491/04
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公开(公告)号：HU173740B
公开(公告)日：1979-08-28
申请号：HUHO001851
申请日：1975-11-05
Applicant: HOECHST AG
Inventor： KUEHLEIN KLAUS , REUSCHLING DIETER-BERND , BABEJ MILOS , BARTMANN WILHELM , BECK GERHARD
IPC: C07D207/26 , C07D207/277
Abstract: The present invention relates to pyrrolidone derivatives which are analogous to natural prostaglandins and to a process for preparing the same. The compounds according to the present invention have prostaglandin-like properties and may be used as pharmaceuticals.
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公开(公告)号：AU2705777A
公开(公告)日：1979-01-18
申请号：AU2705777
申请日：1977-07-15
Applicant: HOECHST AG
Inventor： BARTMANN WILHELM , LERCH ULRICH , TEUFEL HERMANN , SCHOLKENS BERNWARD , BECK GERHARD
IPC: C07D339/08 , A61K31/19 , A61K31/215 , A61P43/00 , C07C67/00 , C07C401/00 , C07C405/00 , C07D317/72 , C07D339/06 , C07C177/00 , C07C121/46 , C07D319/08 , C07D411/08
Abstract: What is disclosed are prostaglandin-analogous cyclopentane derivatives of the formula I wherein R1 is hydrogen or a linear or branched, saturated or unsaturated aliphatic or cycloaliphatic radical having from 1 to 8 carbon atoms, or an araliphatic radical having from 7 to 9 carbon atoms, or a physiologically tolerable metal, NH4 or substituted ammonium ion derived from a primary, secondary or tertiary amine; R2 is a linear or branched, saturated or unsaturated aliphatic hydrocarbon radical having from 1 to 8 carbon atoms; R3 is hydrogen or a R4CO group wherein R4 is a hydrogen atom or a linear or branched alkyl group having up to 10 carbon atoms; A is a saturated, linear or branched alkylene group having from 2 to 5 carbon atoms, and a process for the manufacture thereof.
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公开(公告)号：AU2705677A
公开(公告)日：1979-01-18
申请号：AU2705677
申请日：1977-07-15
Applicant: HOECHST AG
Inventor： BARTMANN WILHELM , LERCH ULRICH , TEUFEL HERMANN , SCHOLKENS BERNWARD
IPC: A61K31/20 , A61K31/23 , A61P43/00 , C07C67/00 , C07C401/00 , C07C405/00 , C07D317/72 , C07D319/08 , C07D333/32 , C07D339/06 , C07D339/08 , C07F9/40 , C07C177/00 , A61K31/135 , A61K31/16 , A61K31/215 , A61K31/34 , A61K31/37 , A61K31/505 , A61K31/55 , A61K31/57 , A61K31/64 , C07C121/46 , C07D307/42 , C07D307/58 , C07D333/16 , C07D409/08
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Patent Agency Ranking
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公开(公告)号：IE71031B1
公开(公告)日：1997-01-15
申请号：IE209988
申请日：1988-07-08
Applicant: HOECHST AG
Inventor： KESSELER KURT , BECK GERHARD , BARTMANN WILHELM , GRANZER ERNOLD
IPC: A61K31/44 , A61K31/365 , A61K31/4418 , A61K31/443 , A61K31/505 , A61P3/06 , A61P9/10 , C07D213/55 , C07D239/26 , C07D405/06 , C07D405/14 , C07F7/18 , A61K31/00
Abstract: 3-Desmethylmevalonic acid derivatives of the formula I ( delta -lactone) or II (corresponding dihydroxycarboxylic acid derivative) … … in which A-B, Z, R , R , R and R have the meanings given, are used as medicaments.
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公开(公告)号：FI96684B
公开(公告)日：1996-04-30
申请号：FI892291
申请日：1989-05-11
Applicant: HOECHST AG
Inventor： JENDRALLA HEINER , WESS GUENTHER , BARTMANN WILHELM , BECK GERHARD
IPC: A61K31/365 , A61K31/185 , A61K31/19 , A61K31/35 , A61K31/366 , A61P3/06 , C07C39/367 , C07C59/64 , C07C59/68 , C07C323/01 , C07C323/09 , C07D309/30
Abstract: Compounds of the general formula I and the corresponding open-chain dihydroxy carboxylic acids of the formula II in which X, Y and Z have the stated meanings, and their pharmacologically tolerated salts with bases and their pharmacologically tolerated esters, process for preparing this compound, its use as pharmaceutical and pharmaceutical products are described. Also described are phenols and thiophenols of the formula III in which X, Y and Z have the stated meanings.
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公开(公告)号：CA1338018C
公开(公告)日：1996-01-30
申请号：CA599613
申请日：1989-05-12
Applicant: HOECHST AG
Inventor： JENDRALLA HEINER , WESS GUENTHER , BARTMANN WILHELM , BECK GERHARD
IPC: A61K31/365 , A61K31/185 , A61K31/19 , A61K31/35 , A61K31/366 , A61P3/06 , C07C39/367 , C07C59/64 , C07C59/68 , C07C323/01 , C07C323/09 , C07D309/30
Abstract: Novel 6-phenoxymethyl-4-hydroxytetrahydropyran-2-ones and 6-thiophenoxymethyl-4-hydroxytetrahydropyran-2-ones and the corresponding dihydroxycarboxylic acid derivatives, salts and esters, processes for the preparation of these compounds, their use as pharmaceuticals, pharmaceutical preparations and novel phenols and thiophenols Novel compounds of the general formula I I and the corresponding open-chain dihydroxycarboxylic acids of the formula II II in which X, Y and Z have the meanings given, and pharmacologically tolerated salts thereof with bases and pharmacologically tolerated esters thereof, processes for the preparation of these compounds, their use as pharmaceuticals and pharmaceutical preparations are described. Novel phenols and thiophenols of the formula III III in which X, Y and Z have the meanings given, are also described.
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100.发明专利
公开(公告)号：HU210722A9
公开(公告)日：1995-06-28
申请号：HU9500067
申请日：1995-01-10
Applicant: HOECHST AG
Inventor： GRANZER ERNOLD , BECK GERHARD , KESSELER KURT , BARTMANN WILHELM
IPC: A61K31/44 , A61K31/365 , A61K31/4418 , A61K31/443 , A61K31/505 , A61P3/06 , A61P9/10 , C07D213/55 , C07D239/26 , C07D405/06 , C07D405/14 , C07F7/18 , C07D213/00 , C07D413/00
Abstract: 3-Desmethylmevalonic acid derivatives of the formula I ( delta -lactone) or II (corresponding dihydroxycarboxylic acid derivative) … … in which A-B, Z, R , R , R and R have the meanings given, are used as medicaments.
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