公开(公告)号：US3649665A

公开(公告)日：1972-03-14

申请号：US3649665D

申请日：1969-04-23

Applicant: TEXACO INC

Inventor： CHAFETZ HARRY ,  BLACKLEY WILLIAM D ,  KREUZ KENNETH L

IPC: C07C45/33 ,  C07C45/36 ,  C07C51/31 ,  C07C201/02 ,  C07C201/04 ,  C07C203/00 ,  C07C205/02 ,  C07C205/06 ,  C07C77/00 ,  C07C77/02 ,  C07C79/02

CPC classification number: C07C201/02 ,  C07C45/33 ,  C07C45/36 ,  C07C51/316 ,  C07C201/04 ,  C07C201/06 ,  C07C2601/14 ,  C07C203/02 ,  C07C203/00 ,  C07C205/06 ,  C07C205/02

Abstract: THIS INVENTION RELATES TO THE RELATIVELY LOW TEMPERATURE TREATMENT OF HYDROCARBONS WITH NITRIC OIDE (NO) AND OXYGEN TO RPODUCE NITRATES, NITRITES AND KETONES AND OTHER OXIDATION PRODUCTS. THROUGH THE USE OF ALKALINE INHIBITORS SUCH AS ALKALI METAL BICARBONATES, THE PRODUCTION OF KETONES AND OTHER NON-NITROGEN CONTAINING OXIDATION PRODUCTS CAN BE MINIMIZED WHILE THE PRODUCTION OF ITRATES AND NITRIES ARE MAXIMIZED.

公开(公告)号：US3377387A

公开(公告)日：1968-04-09

申请号：US59820466

申请日：1966-12-01

Applicant: PURDUE RESEARCH FOUNDATION

Inventor： BRYANT BACHMAN GUSTAVE ,  STRAWN KENNETH G

IPC: C07C45/40 ,  C07C201/06 ,  C07C205/02 ,  C07C205/06 ,  C07C205/15

CPC classification number: C07C201/06 ,  C07C45/40 ,  C07C49/04 ,  C07C205/02 ,  C07C205/06 ,  C07C205/15

公开(公告)号：EP2751064A1

公开(公告)日：2014-07-09

申请号：EP12762554.9

申请日：2012-08-29

Applicant: Bayer Intellectual Property GmbH

Inventor： KNAUF, Thomas ,  MERKEL, Michael

IPC: C07C201/08 ,  C07C201/16 ,  C07C209/36 ,  C07C205/06 ,  C07C211/46

CPC classification number: C07C201/06 ,  C07C201/08 ,  C07C201/16 ,  C07C205/06 ,  C07C209/36 ,  C07C211/46

Abstract: The invention relates to a method for the continuous production of nitrobenzene, wherein crude nitrobenzene is first produced from benzene by nitration and is then washed successively in at least one acidic wash, in at least one alkaline wash and in at least one neutral wash, wherein at least one additional wash with an aqueous solution of a potassium salt is inserted between the last alkaline wash and the first neutral wash.

公开(公告)号：EP2455376A1

公开(公告)日：2012-05-23

申请号：EP12155991.8

申请日：2010-06-10

Applicant: Abbott Laboratories

Inventor： Randolph, John T. ,  Matulenko, Mark A. ,  Keddy, Ryan G. ,  Jinkerson, Tammie K. ,  Hutchinson, Douglas K. ,  Flentge, Charles A. ,  Wagner, Rolf ,  Maring, Clarence J. ,  Tufano, Michael D. ,  Betebenner, David A. ,  Rockway, Todd W. ,  Degoey, David A. ,  Liu, Dachun ,  Pratt, John K. ,  Sarris, Kathy ,  Woller, Kevin R. ,  Wagaw, Seble H. ,  Califano, Jean C. ,  Li, Wenke ,  Caspi, Daniel D. ,  Bellizzi, Mary, E. ,  Gao, Yi ,  Kati, Warren M. ,  Hutchins, Charles W. ,  Donner, Pamela L. ,  Krueger, Allan C. ,  Motter, Christopher E ,  Nelson, Lissa T. ,  Patel, Sachin V.

IPC: C07D403/14 ,  C07D401/14 ,  C07D417/14 ,  A61K31/4025 ,  A61K31/4178 ,  A61K31/4184 ,  A61K31/4196 ,  A61K31/4439 ,  A61P31/14

CPC classification number: C07F9/65583 ,  C07C33/26 ,  C07C201/06 ,  C07C205/19 ,  C07D207/08 ,  C07D207/09 ,  C07D207/16 ,  C07D401/14 ,  C07D403/14 ,  C07D405/14 ,  C07D413/14 ,  C07D417/14 ,  C07D453/00 ,  C07D471/04 ,  C07D491/113 ,  C07K5/06

Abstract: Compounds effective in inhibiting replication of Hepatitis C virus ("HCV") are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.

Abstract translation: 描述了有效抑制丙型肝炎病毒（“HCV”）复制的化合物。 本发明还涉及制备这种化合物的方法，包含这些化合物的组合物，以及使用这些化合物治疗HCV感染的方法。

公开(公告)号：EP2035364A2

公开(公告)日：2009-03-18

申请号：EP07796585.3

申请日：2007-06-29

Applicant: Schering Corporation

Inventor： THIRUVENGADAM, Tiruvettipuram, K. ,  WANG, Tao ,  CHIU, John, S. ,  LIAO, Jing

IPC: C07C201/06 ,  C07C205/55 ,  C07C251/44

CPC classification number: C07C251/44 ,  C07C201/06 ,  C07C249/08 ,  C07C2601/16 ,  C07C205/56 ,  C07C251/42

Abstract: This application discloses provides a process for the introduction of nitro-group functionality into a compound which contains also a site of unsaturation and/or oxygen functionality by direct (one step) oxidation of an oxime functional group mediated by a molybdenum VI/VII peroxo complex, the process comprising: (a) providing a substrate of Formula I containing an oxime functional group; Chemical formula should be inserted here as it appears on the abstract in paper form. wherein R1 and R2 are selected independently from linear, branched or cyclic alkyl and linear, branched or cyclic alkenyl groups, optionally substituted, with the proviso that at least one of R1 or R2 contains a carbon/carbon double bond; and (b) contacting said substrate of Formula I with a molybdenum oxidation complex, thereby oxidizing said oxime functional group to a nitro functional group to yield the structure of Formula III. Chemical formula should be inserted here as it appears on the abstract in paper form. Where R1 and R2 are as defined above.

Abstract translation: 该申请公开提供了一种通过由钼VI / VII过氧配合物介导的肟官能团的直接（一步）氧化将硝基官能团引入到还含有不饱和位和/或氧官能团位点的化合物的方法 该方法包括：（a）提供含有肟官能团的式I的底物; 其中R 1和R 2独立地选自直链，支链或环状的烷基和直链，支链或环状的烯基，任选被取代，条件是R 1或R 2中的至少一个含有碳/碳双键; 和（b）使式I的底物与钼氧化络合物接触，从而将所述肟官能团氧化为硝基官能团，得到式III的结构。 其中R1和R2如上所定义。

公开(公告)号：EP0346185B1

公开(公告)日：1992-12-30

申请号：EP89401485.1

申请日：1989-05-31

Applicant: W.R. Grace & Co.-Conn.

Inventor： Mari, Roger ,  Quibel, Jacques

IPC: C07C205/02 ,  C07C201/10

CPC classification number: C07C201/06 ,  C07C205/02

公开(公告)号：EP0146204B1

公开(公告)日：1988-05-18

申请号：EP84305504.7

申请日：1984-08-13

Applicant: W.R. GRACE & CO.

Inventor： Wang, Shu-chieh Paul ,  Sherwin, Martin B.

IPC: C07C76/02 ,  C07C79/04

CPC classification number: C07C201/06 ,  C07C205/02 ,  C07C205/06

公开(公告)号：EP0146204A3

公开(公告)日：1986-03-05

申请号：EP84305504

申请日：1984-08-13

Applicant: W.R. GRACE & CO.

Inventor： Wang, Shu-chieh Paul ,  Sherwin, Martin B.

IPC: C07C76/02 ,  C07C79/04

CPC classification number: C07C201/06 ,  C07C205/02 ,  C07C205/06

Abstract: Nitroalkanes are selectively formed by contacting, at elevated temperature and pressure and in a homogeneous gas phase, an organic carboxylic acid having from two to ten carbon atoms with N0 2 alone or in the presence of oxygen and/or water.

公开(公告)号：EP2877441B1

公开(公告)日：2016-09-14

申请号：EP13739715.4

申请日：2013-07-23

Applicant: Covestro Deutschland AG

Inventor： KNAUF, Thomas ,  MERKEL, Michael ,  MAIRATA, Antoni

IPC: C07C201/08

CPC classification number: C07C201/06 ,  C07C201/08 ,  C07C205/06

公开(公告)号：EP2751064B1

公开(公告)日：2016-08-10

申请号：EP12762554.9

申请日：2012-08-29

Applicant: Covestro Deutschland AG

Inventor： KNAUF, Thomas ,  MERKEL, Michael

IPC: C07C201/08 ,  C07C201/16 ,  C07C209/36 ,  C07C205/06 ,  C07C211/46

CPC classification number: C07C201/06 ,  C07C201/08 ,  C07C201/16 ,  C07C205/06 ,  C07C209/36 ,  C07C211/46