公开(公告)号：WO2003049803A3

公开(公告)日：2003-06-19

申请号：PCT/US2002/039240

申请日：2002-12-06

Applicant: MEDTRONIC PHYSIO CONTROL MANUFACTURING CORP.

Inventor： STICKNEY, Ronald, E. ,  TAYLOR, James, W. ,  O'HEARN, Patricia ,  JAYNE, Cynthia, P. ,  LANK, Paula ,  HAMPTON, David, R.

IPC: A61B05/00

Abstract: The presence of a cardiac pulse in a patient is determined by evaluating fluctuations in an electrical signal that represents a measurement of the patient's transthoracic impedance. Impedance signal data obtained from the patient is analyzed for a feature indicative of the presence of a cardiac pulse. Whether a cardiac pulse is present in the patient is determined based on the feature in the impedance signal data. Electrocardiogram (ECG) data may also be obtained in time coordination with the impedance signal data. Various applications for the pulse detection of the invention include detection of PEA and prompting PEA-specific therapy, prompting defibrillation therapy and/or CPR, and prompting rescue breathing depending on detection of respiration.

公开(公告)号：WO2003009763A1

公开(公告)日：2003-02-06

申请号：PCT/US2002/023539

申请日：2002-07-24

Applicant: HEALTHETECH, INC.

Inventor： MAULT, James, R.

IPC: A61B05/00

CPC classification number: A61B5/0833

Abstract: A method and apparatus for measuring changes in the concentration of a particular gas component of a breathing gas mixture after inhalation and exhalation by means of a degradable sensor (41). This is done by exposing, during inhalation, the sensor (41) to a breathing gas mixture of known concentration to produce an inhalation output corresponding to the measured concentration of the gas component in the inhalation. From the known concentration of the gas component in the breathing gas mixture and the measured concentration in the inhalation output, a degradation parameter is determined representing the instantaneous degradation condition of the sensor. The sensor (41) is exposed to the breathing gas mixture during exhalation output corresponding to the measured concentration of the gas component in the exhalation; the exhalation output of the sensor (41) is modified according to the determined degradation parameter; and the change in concentration is computed from the modified exhalation output and the measured inhalation output.

Abstract translation: 一种用于测量通过可降解传感器（41）吸入和呼气之后呼吸气体混合物的特定气体组分的浓度变化的方法和装置。 这是通过在吸入期间将传感器（41）暴露于已知浓度的呼吸气体混合物，以产生对应于吸入中测量的气体成分浓度的吸入输出来完成的。 根据呼吸气体混合物中气体成分的已知浓度和吸入输出中测量的浓度，确定表示传感器的瞬时劣化状态的降解参数。 在呼气输出期间，传感器（41）暴露于呼吸气体混合物，对应于呼气中气体成分的测量浓度; 传感器（41）的呼出输出根据确定的劣化参数进行修改; 并且从改进的呼气输出和测量的吸入输出计算浓度的变化。

公开(公告)号：WO2002098296A1

公开(公告)日：2002-12-12

申请号：PCT/US2002/017062

申请日：2002-05-31

Applicant: APEX MEDICAL, INC.

Inventor： REICH, Sanford ,  BULLISTER, Edward, Theodore

IPC: A61B05/00

CPC classification number: A61B5/6876 ,  A61B5/02014 ,  A61B5/0215 ,  A61B5/076 ,  A61B5/6862 ,  A61B2560/0219 ,  A61F2/07 ,  A61F2/90 ,  A61F2002/075 ,  A61F2250/0002

Abstract: An endovascular implant or endograft (18) includes a tubular sleeve having integral inner and outer layers (20, 22). A pressure sensor (S1-3) is embedded between the two layers and is covered thereby. And, the sleeve is flexible at the pressure sensor to permit transfer of pressure through the sleeve for detection by the pressure sensor in use.

Abstract translation: 血管内植入物或内移植物（18）包括具有整体内层和外层（20,22）的管状套筒。 压力传感器（S1-3）嵌入在两层之间，由此覆盖。 并且，套筒在压力传感器处是柔性的，以允许压力通过套筒传递，以便在使用中由压力传感器检测。

公开(公告)号：WO2002065894A3

公开(公告)日：2002-08-29

申请号：PCT/US2002/004648

申请日：2002-02-19

Applicant: DATA SCIENCES INTERNATIONAL, INC.

Inventor： BROCKWAY, Brian ,  DOTEN, Gregory ,  HOLTZ, Michael ,  KALM, Michael, L. ,  KUEHN, Scott ,  LAMBERT, Scott ,  LICHTSCHEIDL, Gregg ,  MILLS, Perry ,  MOSESOV, Oleg ,  NICOLOFF, Demetre, M. ,  ODDEN, Karen ,  PARK, Soon ,  QUINN, Christopher ,  STOFER, Alyse ,  TAYLOR, Jeff ,  VANHEE, Justin ,  ZWIERS, Lynn

IPC: A61B05/00

Abstract: Endocardial pressure measurement devices, systems and methods for effective treatment of congestive heart failure and its underlying causes, in addition to other clinical applications. A representative device includes an implantable pressure measuring system including a pressure transducer (31) and a fluid filled catheter (34), the catheter having a proximal portion (34A) and a distal portion (34B). The proximal portion (34a) is connected to the pressure transducer (31) and the distal portion (34b) has an opening (36) with a barrier (26). The proximal portion (34a) is relatively crush-resistant and the distal portion (34b) is relatively flexible.

公开(公告)号：WO1998036681A1

公开(公告)日：1998-08-27

申请号：PCT/US1997008852

申请日：1997-06-05

Applicant: EMERGING TECHNOLOGY SYSTEMS, LLC ,  PETERS, Richard, K. ,  ELMERICK, Donald

Inventor： EMERGING TECHNOLOGY SYSTEMS, LLC

IPC: A61B05/00

CPC classification number: A61B5/1455 ,  A61B5/14532 ,  A61B5/6816 ,  A61B5/7267 ,  A61B2562/0233 ,  A61B2562/043

Abstract: This invention is a glucose measuring device for determining the concentration of glucose in intravascular blood within a body part of a subject. The device includes at least one light source (12) having a wavelength of 650, 880, 940, or 1300 nm to illuminate the fluid. At least one receptor (14) associated with the light source for receiving light and generating a transmission signal representing the light transmitted is also provided. A support piece is included for supporting the light source associated with the respective receptor. The support piece is adapted to engage a body part of a subject. A method for determining the glucose concentration is also provided which calibrates a measuring device and sets the operating current for illuminating the light sources during operation of the device. Once a transmission signal is generated by receptors (14) receiving light via the light source and illuminated blood, and the high and low values from each of the signals are selected and stored in the device (20), the values are subtracted to obtain a single transmission value for each of the light sources. These calculated values are then compared to a database of target values, either using a neural network, or directly compared to determine the glucose concentration, which value is then displayed (28) on the device.

Abstract translation: 本发明是用于测定受试者体内部血管内血液中葡萄糖浓度的葡萄糖测定装置。 该装置包括至少一个波长为650,880,940或1300nm的光源（12）以照射流体。 还提供了与用于接收光并且产生表示所发射的光的传输信号相关联的至少一个接收器（14）。 包括用于支撑与相应受体相关联的光源的支撑件。 支撑片适于接合被摄体的身体部分。 还提供了用于确定葡萄糖浓度的方法，其校准测量装置并且在装置的操作期间设定用于照射光源的操作电流。 一旦通过经由光源和照射的血液接收光的受体（14）产生传输信号，并且从每个信号中选择并存储在装置（20）中的高和低值，则将这些值减去以获得 每个光源的单传输值。 然后将这些计算值与目标值的数据库进行比较，使用神经网络，或直接比较以确定葡萄糖浓度，然后将该值显示（28）在设备上。

公开(公告)号：WO1998026710A1

公开(公告)日：1998-06-25

申请号：PCT/US1997024263

申请日：1997-12-18

Applicant: NOVAMETRIX MEDICAL SYSTEMS, INC.

Inventor： NOVAMETRIX MEDICAL SYSTEMS, INC. ,  ORR, Joseph, A. ,  KOFOED, Scott, A. ,  WESTENSKOW, Dwayne ,  JAFFE, Michael, B.

IPC: A61B05/00

CPC classification number: A61B5/029 ,  A61B5/0836 ,  A61M16/0045 ,  A61M16/0833 ,  A61M2016/0036 ,  A61M2230/432 ,  G01N33/004 ,  Y02A50/243

Abstract: Apparatus and methods for non-invasively determining cardiac output using partial re-breathing techniques are disclosed in which the apparatus is constructed with an instantaneously adjustable deadspace (70) for accommodating differences in breathing capacities various patients. The apparatus (50) is constructed of inexpensive elements, including a single two-way valve (22) which renders the apparatus very simple to use and inexpensive so that the unit may be readily disposable. The method of the invention provides a novel means (46) of estimating cardiac output based on alveolar CO2 values rather than end-tidal CO2 values as previously practiced. A program for calculating cardiac output is also disclosed.

Abstract translation: 公开了使用部分再呼吸技术非侵入性地确定心输出量的装置和方法，其中该装置构造有瞬时可调的死区（70），用于容纳不同患者的呼吸能力差异。 设备（50）由便宜的元件构成，包括单个二通阀（22），其使得该设备使用起来非常简单并且便宜，使得该单元可以容易地被一次性使用。 本发明的方法提供了一种新颖的方法（46），其基于肺泡二氧化碳值估计心输出量，而不是如先前所述的潮汐CO 2值。 还公开了一种用于计算心输出量的程序。

公开(公告)号：WO1998024360A1

公开(公告)日：1998-06-11

申请号：PCT/CA1997000919

申请日：1997-12-04

Applicant: LUI, Harvey ,  ZENG, Haishan ,  MacAULAY, Calum, E. ,  PALCIC, Branko ,  McLEAN, David, I.

IPC: A61B05/00

CPC classification number: A61B5/444 ,  A61B5/0059 ,  A61B5/0071 ,  A61B2090/502

Abstract: Apparatus for the diagnosis of a skin disease site (3) by visual fluorescence inspection comprising an excitation light source (1)for illuminating the disease site (3), a light guide (2) for transmitting the excitation light directly to the disease site to generate fluorescence light and viewing goggles (4) for processing the excitation light reflected and the fluorescence light emitted from the disease site to provide a fluorescence image of the disease site to a user. The fluorescence image is used to aid the medical assessment of skin conditions and the diagnosis of cutaneous diseases by supplementing the visual assessment of skin lesions made by the naked eye. The apparatus can be used in several modes of operation that permit the viewing of full color fluorescence images and enhanced two color images. The apparatus can also use image intensifying equipment (10) to amplify fluorescence light so that even very weak fluorescing objects can be seen. A method for acquiring and viewing the fluorescence images is also disclosed.

Abstract translation: 用于通过视觉荧光检查诊断皮肤疾病部位（3）的装置，包括用于照射疾病部位（3）的激发光源（1），用于将激发光直接传播到疾病部位的光导（2） 产生荧光和观察护目镜（4），用于处理反射的激发光和从疾病部位发射的荧光，向用户提供疾病部位的荧光图像。 荧光图像用于通过补充肉眼皮肤损伤的视觉评估来帮助对皮肤状况的医学评估和皮肤疾病的诊断。 该装置可以用于允许观看全色荧光图像和增强的双色图像的几种操作模式。 该装置还可以使用图像增强设备（10）来放大荧光，使得甚至可以看到非常弱的荧光物体。 还公开了一种用于获取和观察荧光图像的方法。

公开(公告)号：WO1998020790A1

公开(公告)日：1998-05-22

申请号：PCT/JP1997003977

申请日：1997-10-31

Applicant: CITIZEN WATCH CO., LTD. ,  EGAWA, Shunji

Inventor： CITIZEN WATCH CO., LTD.

IPC: A61B05/00

CPC classification number: G01J5/04 ,  G01J5/045 ,  G01J5/049 ,  G01J5/08 ,  G01J5/0818 ,  G01J5/0875 ,  G01J2005/066 ,  G01J2005/068 ,  H01L2224/48091 ,  H01L2924/00014

Abstract: A light guide tube (15) which guides an infrared radiation from a measured object, a 1st infrared sensor (10) which detects the infrared radiation from the light guide tube (15), a temperature sensor (12) which generates a reference temperature signal, a reference cavity (17) which shows a temperature status approximately the same as the temperature status of the light guide tube (15) and is closed so as to prevent the incidence of an external infrared radiation, a 2nd infrared sensor (11) which detects an infrared radiation from the reference cavity (17), a temperature calculating means (13) which calculates the temperature of the object in accordance with the signals from the 1st infrared sensor (10), the 2nd infrared radiation sensor (11) and the temperature sensor (12) and a display (14) which displays the temperature in accordance with a signal from the temperature calculating means (13) are provided. The diameter of at least one of the light guide tube (15) and the reference cavity (17) is gradually reduced from the side of the 1st and 2nd infrared sensors (10 and 11) toward the light incidence opening of the light guide tube (15).

Abstract translation: 引导来自测量对象的红外辐射的导光管（15），检测来自导光管（15）的红外辐射的第一红外传感器（10），产生参考温度信号的温度传感器 ，参考空腔（17），其显示与导光管（15）的温度状态大致相同的温度状态，并且被封闭以防止外部红外线辐射的入射，第二红外线传感器（11） 根据来自第一红外线传感器（10），第二红外线传感器（11）和第二红外线传感器（11）的信号，检测来自基准空腔（17）的红外线辐射，温度计算装置（13） 提供了根据来自温度计算装置（13）的信号显示温度的温度传感器（12）和显示器（14）。 导光管（15）和基准空腔（17）中的至少一个的直径从第一和第二红外线传感器（10和11）的侧面朝向导光管的光入射开口逐渐减小 15）。

公开(公告)号：WO1998019591A1

公开(公告)日：1998-05-14

申请号：PCT/DE1997002590

申请日：1997-11-03

Applicant: NANOTRON GESELLSCHAFT FÜR MIKROTECHNIK MBH ,  KOSLAR, Manfred

Inventor： NANOTRON GESELLSCHAFT FÜR MIKROTECHNIK MBH

IPC: A61B05/00

CPC classification number: A61N1/3727 ,  H04B7/00

Abstract: A method of wireless communication with a medical device, especially one implanted in the human body. A message input signal (S1, g4) undergoes angular modulation in a transmitter (2 - 8, 16 - 26) and reaches a receiver via a transmission channel (11-15,16 - 26). The transmitter produces angularly modulated pulses having a frequency spectrum and carrying information, in such a way that said pulses can be time-compressed in the transmitter by means of a filter (13) with a frequency dependent transit time, especially a dispersion filter (13,32, 33) so that pulses with reduced duration and higher amplitude can arise, and at least one part of the information that makes up the message is impressed after a further modulation or message technology coding process and is subsequently received and/or at least one part of the information that makes up the message is impressed in addition to the angular modulation.

Abstract translation: 与无线通信的在人体中的方法，特别是植入的医疗装置，其中在发射器的消息输入信号（S1，G4）（2至8个，16至26）进行角度调制，并且通过传输信道向接收机 （11至15，29至37）通过，其中，所述发射机发送所述消息，具有，生成频谱角度调制脉冲，使得这些在所述接收器（11至15，29至37）通过与频率有关的时间的过滤器的装置，特别是一 分散过滤器（13，32,33）是这样的时可压缩，该脉冲发生在发射的脉冲更短的持续时间和增加振幅，进一步地，其中在发送器一侧的脉冲是电信技术的进一步的调制或编码处理之后，在构成信息的消息的印象深刻的至少一部分 接收和/或至少一个对d的部分 构成角调制即消息信息也留下深刻印象。

公开(公告)号：WO1998012962A1

公开(公告)日：1998-04-02

申请号：PCT/US1997015706

申请日：1997-09-05

Applicant: AVITAR, INC.

Inventor： AVITAR, INC. ,  CESARCZYK, Edward, J.

IPC: A61B05/00

CPC classification number: A61B10/0051

Abstract: A specimen collecting device (10) has an elongated foam member (15) that is circumscribed by a hollow tubular member (12) along a portion of its longitudinal axis. The hollow tubular member (12) has a cross-sectional area less than the uncompressed cross-sectional area of the foam member (15) so that the foam member (15) is compressed along the circumscribed portion.

Abstract translation: 样品收集装置（10）具有细长的泡沫构件（15），其沿着其纵向轴线的一部分被中空管状构件（12）外接。 中空管状构件（12）具有小于泡沫构件（15）的未压缩横截面面积的横截面积，使得泡沫构件（15）沿着外接部分被压缩。