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    PLASTIC OPTICAL FIBER AIRWAY IMAGING SYSTEM
    101.
    发明申请
    PLASTIC OPTICAL FIBER AIRWAY IMAGING SYSTEM 审中-公开
    塑料光纤航空成像系统

    公开(公告)号：WO1998014112A2

    公开(公告)日：1998-04-09

    申请号：PCT/US1997017954

    申请日：1997-10-06

    Applicant: UNIVERSITY OF FLORIDA ,  CHOI, Won, Young ,  GRAVENSTEIN, Dietrich ,  LAMPOTANG, Samsun ,  MELKER, Richard ,  WALKER, James, K. ,  GABRIELLI, Andrea

    Inventor： UNIVERSITY OF FLORIDA

    IPC: A61B01/267

    CPC classification number: A61B1/2676 ,  A61B1/0017 ,  A61B1/042 ,  A61B1/07

    Abstract: A system for imaging the human airway having highly advantageous optical and physical characteristics. In a specific embodiment, the human airway can be imaged during the intubation procedure. Plastic fibers are more robust than the glass optical fibers used in currently available imaging systems, and are therefore capable of being bent and/or twisted with less concern of breakage. In addition, the lower costs of plastic fibers enables scopes, in a specific embodiment, to be manufactured for single patient use thereby eliminating the requirement for cleaning, special care, the maintenance of expensive inventory, and most importantly eliminating the opportunity for cross contamination between patients. A further aspect concerns a novel sheath which covers the portion of the imaging system which enters the patient. In this case, the sheath and its optional associated fiber optic illumination is disposable after each use.

    Abstract translation: 一种用于对人类气道进行成像的系统，其具有非常有利的光学和物理特性。 在一个具体实施例中，人气道可以在插管过程中成像。 塑料纤维比当前可用的成像系统中使用的玻璃光纤更坚固，因此能够在较少的断裂的情况下弯曲和/或扭曲。 此外，塑料纤维的较低成本使得在特定实施例中可以制造用于单个患者使用的范围，从而消除对清洁，特殊护理，维护昂贵的库存的要求，并且最重要的是消除了交叉污染的机会 耐心。 另一方面涉及覆盖进入患者的成像系统的部分的新护套。 在这种情况下，护套和其可选的相关联的光纤照明在每次使用之后是一次性的。

    TRANSFORMED WHEAT HAVING IMPROVED BREADMAKING CHARACTERISTICS
    103.
    发明申请
    TRANSFORMED WHEAT HAVING IMPROVED BREADMAKING CHARACTERISTICS 审中-公开
    改良的具有改良的特征的小麦

    公开(公告)号：WO1998007747A1

    公开(公告)日：1998-02-26

    申请号：PCT/US1997014534

    申请日：1997-08-13

    Applicant: UNIVERSITY OF FLORIDA

    Inventor： UNIVERSITY OF FLORIDA ,  VASIL, Indra, K. ,  VASIL, Vimla

    IPC: C07K14/415

    CPC classification number: C07K14/415 ,  C12N15/8242 ,  C12N15/8251

    Abstract: Transgenic plants with increased amounts of high molecular weight glutenin subunits (HMW-GS) have improved breadmaking capability. A specific example of wheat (cv Bob White) transformed to express HMW-GS 1Ax1 is provided. In addition, advantageous uses of the 1Ax1 promoter are described.

    Abstract translation: 具有增加量的高分子量麦谷蛋白亚基（HMW-GS）的转基因植物具有改善的面包制作能力。 提供转化为表达HMW-GS 1Ax1的小麦（cvBob White）的具体实例。 此外，描述了1Ax1启动子的有利用途。

    HYBRID INTERFERON COMPOSITIONS AND METHODS OF USE
    105.
    发明申请
    HYBRID INTERFERON COMPOSITIONS AND METHODS OF USE 审中-公开
    混合干粉组合物及其使用方法

    公开(公告)号：WO1997039127A1

    公开(公告)日：1997-10-23

    申请号：PCT/US1997006114

    申请日：1997-04-11

    Applicant: UNIVERSITY OF FLORIDA

    Inventor： UNIVERSITY OF FLORIDA ,  JOHNSON, Howard, M. ,  SUBRAMANIAM, Prem, S. ,  PONTZER, Carol, H.

    IPC: C12N15/21

    CPC classification number: C07K14/555 ,  A61K38/00 ,  C07K14/56 ,  C07K16/249 ,  C07K2319/00 ,  C07K2319/02

    Abstract: The present invention describes hybrid interferon fusion polypeptides formed of a first segment that contains the N-terminal amino acid sequence of an interferon-tau polypeptide, and a second segment that contains the C-terminal amino acid sequence of a non-tau interferon type I polypeptide. The two segments are joined in the region of a mature interferon polypeptide between about residues 8 and 37. Also described are nucleic acid sequences encoding such interferon fusion polypeptides, expression vectors containing such sequences, and therapeutic applications of the interferon fusion polypeptides. The therapeutic applications include antiviral and anticellular proliferation applications. One advantage of the interferon fusion polypeptides of the present invention is that they do not have cytotoxic side-effects when used to treat cells.

    Abstract translation: 本发明描述了由包含干扰素-τ多肽的N-末端氨基酸序列的第一片段形成的混合干扰素融合多肽，以及包含非τ型干扰素I型的C末端氨基酸序列的第二片段 多肽。 两个片段在大约残基8和37之间的成熟干扰素多肽的区域中连接。还描述了编码这种干扰素融合多肽的核酸序列，含有这种序列的表达载体和干扰素融合多肽的治疗应用。 治疗应用包括抗病毒和抗细胞增殖应用。 本发明的干扰素融合多肽的一个优点是当它们用于治疗细胞时它们不具有细胞毒性副作用。

    LUNG CLASSIFICATION SCHEME, A METHOD OF LUNG CLASS IDENTIFICATION AND INSPIRATORY WAVEFORM SHAPES
    106.
    发明申请
    LUNG CLASSIFICATION SCHEME, A METHOD OF LUNG CLASS IDENTIFICATION AND INSPIRATORY WAVEFORM SHAPES 审中-公开
    肺组分类方法，肺组织鉴定方法及心理波形

    公开(公告)号：WO1997014462A1

    公开(公告)日：1997-04-24

    申请号：PCT/US1996016430

    申请日：1996-10-15

    Applicant: UNIVERSITY OF FLORIDA

    Inventor： UNIVERSITY OF FLORIDA ,  LAMPOTANG, Samsun ,  VAN OOSTROM, Johannes, Hugo, Maria

    IPC: A61M16/00

    CPC classification number: A61M16/204 ,  A61M16/024 ,  A61M2016/0039 ,  A61M2016/0413 ,  A61M2230/432

    Abstract: A method of ventilating a patient comprises initially determining the class of the lungs of a given patient, selecting a pressure or flowrate inspiratory waveform and other ventilatory parameters like inspiratory pause and inspiratory time, among others, appropriate for that lung class, and then ventilating the patient with the selected inspiratory waveform and other ventilatory parameters. New ventilation inspiratory waveforms are provided which have been found to be advantageous for certain lung classes.

    Abstract translation: 通气患者的方法包括：首先确定给定患者的肺类别，选择压力或流量吸气波形以及其他呼吸暂停和吸气时间等通气参数，其中适用于肺类，然后通风 患者选择吸气波形等通气参数。 提供了新的通气吸气波形，这些波形已经被发现对于某些肺类是有利的。

    HYBRID MICROPROCESSOR CONTROLLED VENTILATOR UNIT
    107.
    发明申请
    HYBRID MICROPROCESSOR CONTROLLED VENTILATOR UNIT 审中-公开
    混合微处理器控制的通风机单元

    公开(公告)号：WO1997006844A1

    公开(公告)日：1997-02-27

    申请号：PCT/US1996013304

    申请日：1996-08-16

    Applicant: UNIVERSITY OF FLORIDA

    Inventor： UNIVERSITY OF FLORIDA ,  MELKER, Richard, J. ,  LAMPOTANG, Samsun ,  BLANCH, Paul, B. ,  EULIANO, Neil, R. ,  CAROVANO, Ronald, G. ,  BANNER, Michael, J.

    IPC: A61M16/00

    CPC classification number: A61M16/206 ,  A61M16/0051 ,  A61M16/026 ,  A61M16/0858 ,  A61M16/203 ,  A61M16/205 ,  A61M16/208 ,  A61M16/209 ,  A61M2016/0021 ,  A61M2016/0027 ,  A61M2205/16

    Abstract: A method and apparatus for operating a ventilator in a primary electronic mode or in a back-up pneumatic mode during primary electronic mode failure. A method and apparatus for operating a ventilator in an advanced mode, having a number of ventilatory modes, or in a basic mode, having a limited number of ventilatory modes is also disclosed. A method and apparatus for controlling a ventilator is disclosed wherein the body length of a patient to be ventilated is utilized in determining one or more ventilation parameters. Ventilation limits and alarm settings are also determined in accordance with body length. A method and apparatus is also disclosed for selecting a rate of rise of inspiratory pressure.

    Abstract translation: 一种用于在初级电子模式故障期间以主电子模式或备用气动模式操作呼吸机的方法和装置。 还公开了一种用于以具有有限数量的通气模式的具有多个通气模式或以基本模式操作高级模式的呼吸机的方法和装置。 公开了一种用于控制呼吸机的方法和装置，其中用于确定一个或多个通气参数的待通气患者的体长。 通风限制和报警设置也根据车身长度确定。 还公开了用于选择吸气压力上升率的方法和装置。

    RETROVIRAL SUPERANTIGENS, SUPERANTIGEN PEPTIDES, AND METHODS OF USE
    110.
    发明申请
    RETROVIRAL SUPERANTIGENS, SUPERANTIGEN PEPTIDES, AND METHODS OF USE 审中-公开
    替代性超级细胞，超肽和使用方法

    公开(公告)号：WO1995011975A2

    公开(公告)日：1995-05-04

    申请号：PCT/US1994012499

    申请日：1994-10-31

    Applicant: UNIVERSITY OF FLORIDA

    Inventor： UNIVERSITY OF FLORIDA ,  JOHNSON, Howard, M. ,  TORRES, Barbara, A. ,  YAMAMOTO, Janet, K.

    IPC: C12N15/13

    CPC classification number: C07K14/005 ,  A61K38/00 ,  A61K39/00 ,  C07K16/1045 ,  C12N2740/12022 ,  C12N2740/15022 ,  C12N2740/16322 ,  Y10S930/221

    Abstract: The subject invention concerns novel superantigen proteins and peptides and methods of use of these superantigens. Specifically exemplified are superantigen proteins and peptide antagonists and agonists from mouse mammary tumor virus, feline immunodeficiency virus and human immunodeficiency virus. The proteins and peptides can also be used to produce, purify and detect antibodies that bind to superantigens. These superantigens and their corresponding peptides can be used in both diagnostic and therapeutic protocols.

    Abstract translation: 本发明涉及新型超抗原蛋白和肽以及这些超抗原的使用方法。 具体示例是来自小鼠乳腺肿瘤病毒，猫免疫缺陷病毒和人类免疫缺陷病毒的超抗原蛋白和肽拮抗剂和激动剂。 蛋白质和肽也可用于产生，纯化和检测结合超级抗原的抗体。 这些超抗原及其相应的肽可用于诊断和治疗方案。

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