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    Mammography apparatus
    103.
    发明专利
    Mammography apparatus 有权
    摄影装置

    公开(公告)号：JP2013116214A

    公开(公告)日：2013-06-13

    申请号：JP2011264891

    申请日：2011-12-02

    Applicant: Hamamatsu Photonics Kk ,  浜松ホトニクス株式会社 ,  Hamamatsu Univ School Of Medicine ,  国立大学法人浜松医科大学

    Inventor： SUZUKI TOSHIHIKO ,  YAMASHITA YUTAKA ,  UEDA YUKIO ,  YAMAKI ETSUKO ,  YAMASHITA DAISUKE ,  YOSHIMOTO KENJI ,  SAKAHARA HARUMI ,  OGURA HIROYUKI ,  NASU HATSUKO

    IPC: A61B10/00 ,  A61B8/00

    CPC classification number: A61B5/0091 ,  A61B5/0035 ,  A61B5/708 ,  A61B8/0825 ,  A61B8/4416 ,  A61B2562/046 ,  A61B2562/146 ,  A61B2562/168 ,  G01N21/4795 ,  G01N2021/4797 ,  G01N2201/0826 ,  G01N2201/0833

    Abstract: PROBLEM TO BE SOLVED: To provide a mammography apparatus capable of lessening an impact on the accuracy of interior information due to differences in shapes or sizes of a breast.SOLUTION: A mammography apparatus 1 for illuminating the breast B of a subject A with light, and acquires information of the interior of the breast B by detecting diffuse light, includes a container 3 surrounding the breast B, and a plurality of optical fibers 11 attached toward the inner side of the container 3 and carrying out illumination and detection of the light. The container 3 includes a base member 30 having an opening 30a, a plurality of ring-shaped members 40 communicating with the opening 30a and positioned in series, and a bottom part member 50 positioned on the inner side of the ring-shaped member 40 the furthest from the base member 30. Each ring-shaped member 40 and the bottom part member 50 are configured to be relatively displaceable in the communication direction of either the ring-shaped member 40 adjacent to the base member 30 side or the base member 30. At least part of the plurality of the optical fibers 11 are attached to the plurality of the ring-shaped members 40.

    Abstract translation: 要解决的问题：提供一种能够减轻由于乳房的形状或尺寸的差异对内部信息的精度的影响的乳房X线照相设备。 解决方案：用于通过光照射被检体A的乳房B并通过检测漫射光获取乳房B的内部的信息的乳房照相术设备1包括围绕乳房B的容器3和多个光学 光纤11朝向容器3的内侧安装并进行照明和光的检测。 容器3包括具有开口30a的底座构件30，与开口30a连通并且串联连接的多个环形构件40和位于环形构件40的内侧的底部构件50 每个环形构件40和底部构件50被构造成可以在与基部构件30侧或基底构件30相邻的环形构件40的连通方向上相对移动。 多个光纤11的至少一部分被安装在多个环状部件40上。（C）2013，JPO＆INPIT

    Cell imaging systems and methods
    110.
    发明授权
    Cell imaging systems and methods 有权

    公开(公告)号：US11650149B2

    公开(公告)日：2023-05-16

    申请号：US17040647

    申请日：2019-03-26

    Applicant: Georgia Tech Research Corporation

    Inventor： Francisco Robles ,  Patrick Ledwig

    IPC: G01N21/41 ,  G01N33/483 ,  G02B21/36 ,  G02B21/06 ,  G06K9/00 ,  G06V20/69

    CPC classification number: G01N21/41 ,  G01N33/4833 ,  G02B21/06 ,  G02B21/365 ,  G06V20/693 ,  G06V20/698 ,  G01N2021/418 ,  G01N2201/061 ,  G01N2201/062 ,  G01N2201/0826

    Abstract: Disclosed herein are systems and methods for imaging cells. Quantitative phase imaging uses variations in the index of refraction of a sample as a source of endogenous contrast, providing label-free information of sub-cellular structures and allowing for the reconstruction of valuable biophysical parameters, such as cell dry-mass at femtogram scales, mass transport, and sample thickness and fluctuations at nanometer scales. As a result, QPI has become a valuable tool in biology and medicine. However, QPI has suffered from the need for trans-illumination through relatively thin objects in order to gain access to the forward-scattered field, which carries crucial low spatial frequency information of a sample and avoid contributions from multiple scattered light or out-of-focus planes. The disclosed methods and systems can provide for reconstruction of QPI and corresponding analysis for imaging samples of cells in thick samples using an epi-illumination configuration.

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