公开(公告)号：WO1996025092A1

公开(公告)日：1996-08-22

申请号：PCT/US1995015671

申请日：1995-12-01

Applicant: MEDWAVE, INC.

Inventor： MEDWAVE, INC. ,  ARCHIBALD, G., Kent ,  CURAN, Timothy, G. ,  DANIELSON, Orland, H. ,  POLIAC, Marius, O. ,  THEDE, Roger, C.

IPC: A61B05/02

CPC classification number: A61B5/02116 ,  A61B2562/0247

Abstract: The present invention is a method for locating a sensor (38) over an underlying artery having a blood pulse. The sensor (38) is positioned at a plurality of locations above a known approximate location of the artery while applying a hold down pressure to the artery. Waveform pressure data are sensed at each one of the plurality of locations. The sensor (38) is positioned over the underlying artery based upon the sensed waveform pressure data at each one of the plurality of locations.

Abstract translation: 本发明是用于在具有血液脉冲的下部动脉上定位传感器（38）的方法。 传感器（38）位于动脉的已知大致位置上方的多个位置处，同时向动脉施加压力。 在多个位置的每个位置处感测波形压力数据。 基于在多个位置中的每个位置处的感测波形压力数据，传感器（38）位于下面的动脉上方。

公开(公告)号：WO1995005115A2

公开(公告)日：1995-02-23

申请号：PCT/US1994009064

申请日：1994-08-11

Applicant: THERMAL TECHNOLOGIES, INC.

Inventor： THERMAL TECHNOLOGIES, INC. ,  BOWMAN, Harry, F.

IPC: A61B05/02

CPC classification number: A61B5/028 ,  A61B5/029

Abstract: A technique for determining blood flow in a living body by changing the thermal energy level by a predetermined amount at a site in a blood flow path and detecting temperatures at locations upstream and downstream of the site. The temperature difference at such locations is determined and the blood flow is calculated as a function of the change in energy level and of the temperature differences measured prior to and following the change in energy level.

Abstract translation: 一种用于通过在血流路径中的位置处将热能水平改变预定量并检测位置上游和下游位置处的温度来确定生物体中的血流量的技术。 确定这些位置处的温度差，并且根据能量水平的变化以及能量水平变化之前和之后测量的温度差来计算血流量。

公开(公告)号：WO1995000070A1

公开(公告)日：1995-01-05

申请号：PCT/FI1994000277

申请日：1994-06-21

Applicant: INCREA OY ,  SEPPONEN, Raimo, Erik

Inventor： INCREA OY

IPC: A61B05/02

CPC classification number: A61B5/681 ,  A61B5/0002 ,  A61B5/02241 ,  A61B5/02438 ,  A61B5/0285 ,  A61B5/0404

Abstract: The invention concerns an apparatus for registration of the human blood pressure and other quantities belonging to the blood circulation system. The apparatus contains a bracelet (WB) having first cuff means (MA) to load the wrist artery and means (PA) for registration of pressure variations (MPP) and pressure (MP) in the first cuff means (MA). The apparatus contains also second cuff means (MB) to load the wrist in an area beside the first cuff means. The apparatus may also contain a wrist unit (WU) with electrode means (RE, BPE) to registrate an EKG-signal, means (CPU) for analysing the registrated signals and a display (DD) for indicating the results.

Abstract translation: 本发明涉及用于人血压登记和属于血液循环系统的其它量的装置。 该装置包括具有装载手腕动脉的第一箍带装置（MA）和用于在第一袖带装置（MA）中记录压力变化（MPP）和压力（MP））的装置（PA）的手镯（WB）。 该装置还包括将腕部装载在第一袖带装置旁边的区域中的第二袖带装置（MB）。 该装置还可以包含具有用于注册EKG信号的电极装置（RE，BPE）的手腕单元（WU），用于分析注册信号的装置（CPU）和用于指示结果的显示器（DD）。

公开(公告)号：WO1994004074A1

公开(公告)日：1994-03-03

申请号：PCT/JP1993001176

申请日：1993-08-23

Applicant: MATSUSHITA ELECTRIC WORKS, LTD. ,  IWAI, Nobuo

Inventor： MATSUSHITA ELECTRIC WORKS, LTD.

IPC: A61B05/02

CPC classification number: A61B5/02225 ,  A61B5/022 ,  A61B5/0225

Abstract: A pressure information separating means (24) is adapted to separate a pressure in a cuff obtained through an A/D converter (23) into a cuff pressure and an arterial pulse wave component. A measurement value of form reflective of the waveform of one arterial pulse wave is determined by an arterial pulse wave extracting means (24a). An arithmetic means (26) is adapted to detect a feature value in the time sequence of the measurement value of form, and determined maximum and minimum blood pressure values on the basis of a cuff pressure corresponding to the feature value of the measurement value of form. Since the points in time of maximum and minimum blood pressure values are determined on the basis of the waveform of the arterial pulse wave, the occurrence of an error due to an individual difference can be minimized, and a blood pressure can be measured accurately.

Abstract translation: 压力信息分离装置（24）适于将通过A / D转换器（23）获得的袖带中的压力分离成袖带压和动脉脉搏波分量。 通过动脉脉波提取装置（24a）确定反映一个动脉脉搏波形的形状的测量值。 算术装置（26）适于根据与形式的测量值的特征值相对应的袖带压力来检测形状的测量值的时间顺序中的特征值，以及确定的最大和最小血压值 。 由于基于动脉脉搏波的波形来确定最大血压值和最低血压值的时间点，所以能够使由个体差异引起的误差的发生最小化，能够精确地测定血压。

公开(公告)号：WO1992022240A1

公开(公告)日：1992-12-23

申请号：PCT/US1992005038

申请日：1992-06-12

Applicant: ABBOTT LABORATORIES

Inventor： ABBOTT LABORATORIES ,  HUGHES, Timothy, J.

IPC: A61B05/02

CPC classification number: A61B5/028 ,  A61B5/029

Abstract: A heated catheter for monitoring cardiac output. Displaced from a distal end of a heated catheter (30) is a resistive heater (32) that heats blood flowing within a heart muscle (10). The resistive heater is mounted on the catheter so that when the catheter is inserted into the heart, the resistive heater is disposed in the right ventricle. A temperature sensor (34) is disposed downstream of the resistive heater, in or proximate the pulmonary artery during use. A differential amplifier (40, 70) provides an electrical current to the resistive heater that varies as a function of the difference between the temperature of the resistive heater, measured by a temperature sensor (35), and a predetermined temperature. In another embodiment of the invention, a resistive heater (90) has a resistance that varies with temperature. The resistive heater comprises one arm of a bridge circuit (85). A differential amplifier (110) provides an electrical current to the bridge circuit in response to the voltage developed across the bridge circuit.

公开(公告)号：WO1992011804A1

公开(公告)日：1992-07-23

申请号：PCT/US1992000408

申请日：1992-01-14

Applicant: KRAIDIN, Jonathan ,  GRATZ, Irwin

IPC: A61B05/02

CPC classification number: A61B5/029 ,  A61B5/021 ,  A61B5/02108

Abstract: A method for continuously determining cardiac output (CO) in a subject comprising continuously measuring arterial blood pressure data at a site and converting said arterial blood pressure data to a digital signal representative of a pulse contour curve waveform, calculating heart rate, grade of slope, systolic peak pressure, the presence of reflected waves, and pressure at the dicrotic notch from said digital signal; determining the area, SA, under said pulse contour curve from the start of a pulse to the dicrotic notch of said pulse contour curve; for any pulse which is reflective, subtracting from said area A any portion, B, of said area A, representing an approximate area due to wave reflection to obtain a stroke area, SA; and calculating CO as a product of SA and HR. Apparatus for continuously determining cardiac output (CO) in a subject comprising means for carrying out each step of the method are also disclosed.

公开(公告)号：WO1991017702A1

公开(公告)日：1991-11-28

申请号：PCT/US1991003069

申请日：1991-05-03

Applicant: KUNIG, Horst, E.

IPC: A61B05/02

CPC classification number: A61B5/0205

Abstract: A monitoring device for cardiac efficiency receives signals representative of volume and pressure of the ventricle, oxygen consumption and heart rate and processes these signal to determine distinct energy levels during a cardia cycle to delineate preload and afterload potentials. Cardiac efficiency is then determined as the energy transferred in a transition from the preload level to the afterload level as related to the preload level. Circulatory efficiency is determined as the ratio of transition energy over metabolic rate. Stroke and cardiac deficiency are determined by the ratio of stroke and cardiac preload/afterload potential band overlap divided by maximum stroke and cardiac preload potential, respectively. Circulatory deficiency is determined by the ratio of cardiac preload/afterload potential band overlap divided by the metabolic rate.

Abstract translation: 用于心脏效能的监测装置接收表示心室的体积和压力，氧消耗和心率的信号，并处理这些信号以确定贲门周期期间的不同能级，以描绘预负荷和后负荷电位。 然后将心脏效率确定为在与预负载水平相关的从预负载水平到后负荷水平的转变中传递的能量。 循环效率被确定为过渡能量与代谢率的比值。 脑卒中和心脏缺血的发生率分别由卒中和心脏预负荷/负荷后电位带重叠除以最大卒中和心脏预负荷电位之比决定。 循环不足取决于心脏预负荷/后负荷潜能带重叠除以代谢率的比例。

公开(公告)号：WO1991017700A1

公开(公告)日：1991-11-28

申请号：PCT/JP1991000658

申请日：1991-05-17

Applicant: MITSUBISHI RAYON CO., LTD. ,  IWASAKI, Hitoshi

Inventor： MITSUBISHI RAYON CO., LTD.

IPC: A61B05/02

CPC classification number: A61B5/0261 ,  A61B5/1459 ,  A61B2562/0238

Abstract: A catheter for measurement comprising light emitting and light receiving optical fibers inserted into the catheter in which respective tip surfaces of both optical fibers are disposed face-to-face and apart from each other at a required distance on the outer wall of the catheter and fixed thereto. Rays of light for measurement and reference are emitted from the light emitting fiber of the catheter and, by measuring the degree of penetration of said two kinds of light emitting from the light receiving optical fiber after passing through blood present between the tip surfaces of both optical fibers, an oxygen saturation degree or flowing speed of blood can be found in real time.

公开(公告)号：WO1990008502A1

公开(公告)日：1990-08-09

申请号：PCT/US1990000453

申请日：1990-01-29

Applicant: MARTIN GOFFMAN ASSOCIATES

Inventor： MARTIN GOFFMAN ASSOCIATES ,  SHI, Weimin

IPC: A61B05/02

CPC classification number: A61B5/02154 ,  G01L9/0077

Abstract: A device for the measurement of the blood pressure of a patient comprising means for producing a light (8) through an optical fiber (6), means for receiving and measuring (7, 11-17) the reflected light through a second optical fiber (5), and a cylindrically shaped pressure sensor (1) having a side window (27) and a plate (28) having two sections (33 and 34) which moves in accordance with the applied blood pressure thereby causing the reflection and detection of different amounts of light based on the applied blood pressure.

公开(公告)号：WO1990002512A1

公开(公告)日：1990-03-22

申请号：PCT/US1989003861

申请日：1989-09-12

Applicant: HON, Edward, H. ,  HON, Edward, D. ,  HON, Robert, W.

IPC: A61B05/02

CPC classification number: A61B5/02241

Abstract: An improved apparatus (10) and method for continously measuring cutaneous blood pressure is disclosed. A portion of cutaneous tissue, preferably from a digit such as a finger or toe, is isolated by an isolation ring (21), and a pressure sensing device (24) associated with the isolation ring (21) measures the changes in pressure in the isolated cutaneous tissue. The pressure sensing device (24) is connected to a hollow digit support member (12) by a transducer support member (22).

Abstract translation: 公开了一种用于连续测量皮肤血​​压的改进装置（10）和方法。 皮肤组织的一部分，优选地来自诸如手指或脚趾的数字，通过隔离环（21）隔离，并且与隔离环（21）相关联的压力感测装置（24）测量压力变化 分离皮肤组织。 压力感测装置（24）通过换能器支撑构件（22）连接到中空的数字支撑构件（12）。