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公开(公告)号：WO2009118718A1
公开(公告)日：2009-10-01
申请号：PCT/IE2009/000011
申请日：2009-03-27
Applicant: STAMFORD DEVICES LIMITED , CLANCY, Dermot, Joseph , DUFFY, Conor , GIBBONS, Keith , POWER, John , SMITH, Niall
Inventor： CLANCY, Dermot, Joseph , DUFFY, Conor , GIBBONS, Keith , POWER, John , SMITH, Niall
CPC classification number: A61B17/3474 , A61M11/005 , A61M11/042 , A61M15/0085 , A61M15/025 , A61M16/0833 , A61M16/147 , A61M16/16 , B05B12/081 , B05B17/0646 , B05B17/0669
Abstract: A method for humidifying gas in a ventilator circuit 100, 101, 102, 105. 106 comprises aerosolising a humidifying agent such as water or saline using aerosol generator 2 and delivering the aerosolised humidifying agent, to the inspiration line 101 of the ventilator circuit coupled to the respiratory system of a patient. The aerosol generator 2 comprises a vibratable member 40 having a plurality of apertures extending between a first surface and a second surface. A controller 3 controls the operation of aerosol generator 2, for example in response to the flow of air in the inspiration line 101 as detected by a sensor11.
Abstract translation: 用于使呼吸器回路100,101,102,105,106中的气体增湿的方法包括使用气溶胶发生器2将诸如水或盐水的增湿剂雾化并且将雾化的增湿剂递送至吸气器 呼吸机回路的管线101连接到患者的呼吸系统。 气雾发生器2包括具有在第一表面和第二表面之间延伸的多个孔的可振动构件40。 控制器3例如响应于由传感器11检测到的吸气管线101中的空气流动来控制气雾发生器2的操作。
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公开(公告)号：WO2008117264A1
公开(公告)日：2008-10-02
申请号：PCT/IE2008/000031
申请日：2008-03-28
Applicant: STAMFORD DEVICES LIMITED , POWER, John, Sylvester , SMITH, Niall, Scott , DUFFY, Conor, Paul , GIBBONS, Keith , DIEMUNSCH, Pierre, Auguste
Inventor： POWER, John, Sylvester , SMITH, Niall, Scott , DUFFY, Conor, Paul , GIBBONS, Keith , DIEMUNSCH, Pierre, Auguste
CPC classification number: A61B17/3474 , A61M11/005 , A61M13/00 , A61M13/003 , A61M2202/0225 , A61M2202/025 , A61M2202/0266 , A61M2202/0291 , B05B12/081 , B05B17/0646 , B05B17/0669
Abstract: Apparatus used in insufflation comprises an insufflator 12 for generating an insufflation gas such as carbon dioxide and an aerosol generator 2 for aerosolising a fluid and entraining the aerosol with the insufflation gas. The aerosol generator 2 comprises a vibratable member 40 having a plurality of apertures extending between a first surface and a second surface. The fluid may comprise a therapeutic or prophylactic agent. A controller 3 is used to control the operation of the aerosol generator 2. The controller 3 controls operation of the aerosol generator 2 responsive to the flow of insufflation gas such as detected by a flow sensor 11.
Abstract translation: 用于吹入的装置包括用于产生诸如二氧化碳的吹入气体的吹入器12和用于使气体雾化并用吹入气体夹带气溶胶的气溶胶发生器2。 气溶胶发生器2包括具有在第一表面和第二表面之间延伸的多个孔的可振动构件40。 流体可以包含治疗剂或预防剂。 控制器3用于控制气溶胶发生器2的操作。控制器3响应于诸如由流量传感器11检测的吹入气体的流动来控制气溶胶发生器2的操作。
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公开(公告)号：US20250082869A1
公开(公告)日：2025-03-13
申请号：US18726062
申请日：2022-11-07
Applicant: CANSINO BIOLOGICS INC. , STAMFORD DEVICES LIMITED
Inventor： Weixue SI , Xiaolong ZHAO , Yueran WANG , Yueying JIANG , Liping WANG , Xuefeng YU , Shoubai CHAO , Tao ZHU
IPC: A61M11/00
Abstract: Disclosed are a nebulization cup and application in nebulized inhalation administration thereof, and especially application in nebulized inhalation administration of a preventive and/or therapeutic drug for a respiratory disease (such as SARS-CoV-2 vaccine). After adding an antistatic agent, the nebulization cup can effectively maintain the stability of drug mist within a certain period of time, with stable particle size, less drug residue in the cup, thus ensuring effective inhalable amount, and the administration operation is simple and convenient, thus the nebulization cup can significantly improve the inoculation efficiency and can be used for large-scale inoculation.
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公开(公告)号：USD1062035S1
公开(公告)日：2025-02-11
申请号：US29784886
申请日：2021-05-21
Applicant: STAMFORD DEVICES LIMITED
Designer： Colm Carmody , Micheal Casey , John Merrigan
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公开(公告)号：US20240207881A1
公开(公告)日：2024-06-27
申请号：US18551731
申请日：2022-03-16
Applicant: STAMFORD DEVICES LIMITED
Inventor： Michael TIMOTHY
CPC classification number: B05B17/0607 , B06B1/0688 , A61M11/005 , B06B2201/77
Abstract: An acrosol generator core (1) has an integral body (2) and membrane (4), and a vibratory drive connected to an electrical voltage supply. In some examples the body provides the vibration drive and comprises a piezoelectric polymer (2) of P(VDF-TrFE) material. In this manner a single manufacturing operation can provide the membrane. the support. and the vibration drive. and operations such as attaching a membrane to an annular support are avoided.
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Patent Agency Ranking
公开(公告)号：US11998678B2
公开(公告)日：2024-06-04
申请号：US17194369
申请日：2021-03-08
Applicant: Stamford Devices Limited
Inventor： Joseph Grehan , Michael Casey , Shaun Porter , Niall Smith
CPC classification number: A61M11/00 , A61M11/005 , B05B15/14 , B05B17/0646 , B05B17/0669 , B06B1/0253 , A61M2205/3317 , A61M2205/3386 , A61M2205/50 , A61M2205/583 , B05B12/081 , B06B2201/77
Abstract: A digital processor of a nebulizer controller controls and monitors drive current (I) applied to an aperture plate. The drive current is detected as a series of discrete values at each of multiple measuring points, each having a particular drive frequency The processor in real time calculates a slope or rate of change of drive current with frequency and additionally determines a minimum value for drive current leading up to the peak value. The processor uses both the value of the minimum drive current during the scan and also the maximum slope value to achieve reliable prediction of end of dose, when the aperture plate becomes dry.
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公开(公告)号：US11872573B2
公开(公告)日：2024-01-16
申请号：US17818484
申请日：2022-08-09
Applicant: Stamford Devices Limited
Inventor： Brendan Hogan , Hong Xu
CPC classification number: B05B1/02 , B05B17/0638 , B05B17/0653 , C25D1/08 , C25D7/04 , A61M11/005 , A61M15/0085 , A61M2207/00
Abstract: An aperture plate is manufactured by plating metal around a mask of resist columns having a desired size, pitch, and profile, which yields a wafer about 60 μm thickness. This is approximately the full desired target aperture plate thickness. The plating is continued so that the metal overlies the top surfaces of the columns until the desired apertures are achieved. This needs only one masking/plating cycle to achieve the desired plate thickness. Also, the plate has passageways formed beneath the apertures, formed as an integral part of the method, by mask material removal. These are suitable for entrainment of aerosolized droplets exiting the apertures.
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公开(公告)号：US11839891B2
公开(公告)日：2023-12-12
申请号：US16621604
申请日：2018-08-23
Applicant: STAMFORD DEVICES LIMITED
Inventor： Joseph Grehan , Noel Coyle , Russell Greaney , Stephen Thornton
CPC classification number: B05B12/081 , A61M11/005 , A61M15/0085 , B05B17/0646 , B05B17/0669 , A61M2205/3317 , A61M2205/50
Abstract: An aerosol delivery system has an aerosol generator with a vibrating aperture plate (10) and an actuator (11, 16, 17, 19), a controller (18, 19). The controller in real time monitors (201) the aerosol generator as it is driven for vibration of the aperture plate, and detects (202) a change in an electrical characteristic in response to a transition from a wet state to a dry state of the aperture plate. It automatically modifies (203, 205, 206), during the transition, operation of the aerosol generator in response to the detected change. The modification includes reducing applied power (203). The controller continues (204) to monitor during the transition, including monitoring the aperture plate for presence of residual liquid on the aperture plate first surface. The controller monitors at a number of drive frequencies and maintains data representing trends in a combination of the electrical characteristic signals at the different frequencies, and identifies a start of a transition if a calculated value rises above a threshold. There is one threshold for triggering a check scan for residual volume and a higher threshold to trigger an immediate shut down.
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公开(公告)号：US20230381429A1
公开(公告)日：2023-11-30
申请号：US18446553
申请日：2023-08-09
Applicant: Stamford Devices Limited
Inventor： Patrick Joseph POWER , Jimmy EATON-EVANS
CPC classification number: A61M11/02 , A61M15/0021 , A61M16/06 , A61M15/0085 , A61M16/208 , A61M11/003
Abstract: A system for delivery of aerosol therapy to spontaneously breathing patients comprises a housing which defines a chamber. The housing has a base, a top and a main body extending between the base and the top. An ambient air inlet is located adjacent to the base and is normally closed by an inlet valve. The housing also has a patient port for receiving a mouthpiece or a face mask. The mouthpiece has an exhaust outlet closed by an exhaust valve. Similarly, the face mask has an exhaust outlet closed by an exhaust valve. Exhaled air is exhausted through the valves and to prevent recirculation through the chamber which would adversely affect dose efficiencies. The housing also has an aerosol port for receiving a vibrating mesh aerosol generating device. The aerosol port is located in a side of the main body of the housing for delivery of aerosol into the chamber between the inlet valve and the patient port. A boss extends upwardly from the base and is spaced-apart inwardly of the main body of the housing to define a reception space or well.
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公开(公告)号：US20230182162A1
公开(公告)日：2023-06-15
申请号：US18045543
申请日：2022-10-11
Applicant: Stamford Devices Limited
Inventor： Ronan MACLOUGHLIN , Conor Paul DUFFY , Brendan HOGAN , Patrick Martin KELLY
CPC classification number: B05B17/0646 , A61M11/003 , A61M11/005
Abstract: A method for aerosolising a liquid comprises the steps of: —providing an aperture plate having at least 100 outlet holes per mm; delivering liquid to the aperture plate; and vibrating the aperture plate to produce an aerosol. The viscosity of the liquid is in the range of from 1 to 15 cP and the surface tension of the liquid is in the range of from 72 to 0.5 mN/m. The output rate of the generated aerosol is greater than 0.01 mL/min.
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