Abstract:
PURPOSE: A method for discriminating a sasang constitution is provided to calculate water and oil by measuring the amount of water and oil of a facial skin. CONSTITUTION: An amount of water and oil of a facial skin is measured. A water and oil component index is calculated. The water and oil component index is a ratio of oil to water. A target for discriminating a sasang constitution is classified into age more than 36 and the age less than 35.
Abstract:
PURPOSE: A composition containing medicinal herb extract is provided to promote adipocyte differentiation and to enhance anti-wrinkling, elasticity enhancement and anti-aging. CONSTITUTION: A composition for skin elasticity, anti-wrinkling, and anti-aging contains extract of Rehmannia glutinosa, Radix glycyrrhizae, Semen coicis, Fructus hordei, Fructus chaenomelis, Cortex acanthopanacis, and Radix puerariae as an active ingredient. An external use composition contains the extract as an active ingredient.
Abstract:
PURPOSE: A composition containing medicinal herb extract for skin care or plasty is provided to promote differentiation of mesenchymal stem cells to adipocytes. CONSTITUTION: A composition for promoting adipocyte differentiation contains Linderae Radix extract as an active ingredient. The composition increases fat tissue and promotes differentiation of mesenchymal stem cells to adipocytes. The mesenchymal stem cells are derived from human bone marrow.
Abstract:
PURPOSE: A cosmetic composition containing Panax ginseng C.A. Meyer powder is provided to ensure scrub effect and to promote blood circulation on the face. CONSTITUTION: A cosmetic composition contains Panax ginseng C.A. Meyer powder. The size of Panax ginseng C.A. Meyer powder is 150um to 450 um. The cosmetic composition is used in the form of toner, emulsion, essence, cleansing cream, BB cream, foundation, or pack.
Abstract:
PURPOSE: An external use skin composition containing pine root extract is provided to remove free radical, to protect cellular membrane damage, and to suppress reactive oxygen species(ROS). CONSTITUTION: An external use skin composition contains pine root extract. The composition is used for anti-aging, and cell protection by promoting HSP70 generation. The external use skin composition contains 0.001-99 weight% of pine root extract based on total weight. The composition further contains cosmetically and dermatologically acceptable medium and/or substrate. The composition is used in the form of solution, gel, solid, emulsion, suspension, microemulsion, microcapsule, cream, skin, lotion, or spray. The composition is used for anti-aging and skin regeneration.
Abstract:
PURPOSE: A cosmetic composition containing stabilized leontopodic acid is provided to suppress collagenase expression and collagen synthesis, and to ensure anti-wrinkle. CONSTITUTION: A cosmetic composition for anti-wrinkle contains 0.00001-10 weight% of leontopodic acid of chemical formula 1 as an active ingredient. The leontopodic acid is isolated from Leontopodium alpinum using hydrous or anhydrous low alcohol, water, or acetone and by extracting again with ethyl acetate, diethylether, benzene, chloroform, or hexane.
Abstract:
PURPOSE: A method for screening a material which relieves skin irritation by environmental harmful factor is provided to manufacture an external use formulation and to detoxify. CONSTITUTION: A method for screening a material which relieves skin irritation by environmental harmful factor comprises: a step of treating candidates which regulates intracellular factor in vitro; a step of treating the environmental harmful factor to test cells to induce overexpression of the factor; and a step of measuring expression level. The test cells are keratinocytes. The environmental harmful factor is pollen or yellow sand. The overexpressed factor is interleukin 6 or 8, GSTT1, NQ01, or hBD3. The screened material is Melia azedarach L. var. japonica Makino or Tussilago farfara L. extract.
Abstract:
PURPOSE: A skin composition for external use containing Broussonetiae Fructus extract is provided to ensure skin barrier strengthening and skin moisturization and to be used in cosmetic products and in the medicinal field. CONSTITUTION: A composition for external use contains Broussonetiae Fructus extract as an active ingredient. The Broussonetiae Fructus extract enhances PPARs(peroxisome proliferator-activated receptors), fillatrin, trasglutaminase 1(TGase 1), or an hyaluronic acid synthase 1(HAS2) gene expression. The composition is used in the form of a lotion, eye cream, nutrition cream, massage cream, cleansing cream, cleansing foam, cleansing water, powder, essence, pack, or ointment.
Abstract:
PURPOSE: A method for screening a material which induces skin irritation by yellow dust is provided to reduce skin irritative factor expression and to reduce skin irritation by yellow dust. CONSTITUTION: A method for screening a material which induces skin irritation by yellow dust comprises: a step of treating yellow dust to keratinocytes; and a step of screening a gene of which expression level is significantly changed comparing with the expression of normal keratinocytes through RT-PCR. The material which induces skin irritation by yellow dust is AhR or CYP. A method for screening a material which relieves skin irritation by yellow dust comprises: a step of treating yellow dust to test cells to induce overexpression of an irritative factor; a step of treating a candidate material to the overexpressed cells; a step of measuring expression level of the irritative factor by RT-PCR. The material which relieves skin irritation by yellow dust is Trichosanthis semen. An external use skin composition for relieving skin irritation contains 0.001-1 weight% of Trichosanthis semen.
Abstract:
PURPOSE: An external use skin composition for skin whitening containing natural products extract is provided to ensure skin whitening effect and melanogenesis suppression with stability to the skin. CONSTITUTION: An external use skin composition contains extract of Oldenlandia Diffusa Willd, Rheum undulatum LINNE, and Broussonetia kazinoki Sieb as an active ingredient. The extract of Oldenlandia Diffusa Willd, Rheum undulatum LINNE, and Broussonetia kazinoki Sieb is mixed in a weight ratio of 1-4:1-4:1-4.