公开(公告)号：EP3063523A4

公开(公告)日：2017-06-28

申请号：EP14857971

申请日：2014-10-31

Applicant: 3SCAN INC

Inventor： GOODMAN MATTHEW ,  DANIEL CODY

IPC: G01N1/06

CPC classification number: G02B21/362 ,  B26D5/007 ,  G01N1/06 ,  G01N1/286 ,  G01N21/55 ,  G01N2001/2873 ,  G01N2201/02 ,  G01N2201/06113 ,  G02B21/002 ,  G02B21/32

公开(公告)号：EP3175220A2

公开(公告)日：2017-06-07

申请号：EP15745743.3

申请日：2015-07-27

Applicant: Nanometrics Incorporated

Inventor： KLASSEN, Andrew S. ,  HAZELTON, Andrew J. ,  BARADA, Andrew H. ,  PETIT, Todd M. ,  TU, Chuan Sheng

IPC: G01N21/15 ,  G03F7/20

CPC classification number: G01N21/4785 ,  G01N21/01 ,  G01N21/15 ,  G01N2021/151 ,  G01N2201/02 ,  G01N2201/068 ,  G03F7/70933

Abstract: An integrated metrology module includes a chuck for holding a sample and positioning the sample with respect to an optical metrology device, a reference chip for the optical metrology device, the reference chip being movable to various positions with respect to the optical metrology device, and a reference chip purge device provides a flow of purge gas or air over the reference chip while the reference chip is in the various positions. The reference chip purge device may be static or movable with the reference chip.

Abstract translation: 集成度量模块包括用于保持样本并相对于光学度量装置定位样本的卡盘，用于光学度量装置的参考芯片，参考芯片可相对于光学度量装置移动到各种位置，以及 参考芯片吹扫装置在参考芯片处于不同位置时提供吹扫气体或空气在参考芯片上的流动。 参考芯片清除装置可以是静态的或者可以与参考芯片一起移动。

公开(公告)号：EP2981800A4

公开(公告)日：2017-03-29

申请号：EP14779160

申请日：2014-04-02

Applicant: BTG INSTR AB

Inventor： ANDERSSON NICLAS ,  SKÅLÉN BENGT ANDERS ,  NORDER STIG

IPC: G01N1/28 ,  G01N1/10 ,  G01N1/20 ,  G01N1/34 ,  G01N1/38 ,  G01N1/40 ,  G01N21/47 ,  G01N21/55 ,  G01N21/59 ,  G01N33/34

CPC classification number: G01N1/2035 ,  G01N1/34 ,  G01N1/38 ,  G01N21/4738 ,  G01N21/55 ,  G01N21/59 ,  G01N33/343 ,  G01N2001/1025 ,  G01N2001/205 ,  G01N2001/4088 ,  G01N2201/02

Abstract: A device for sampling, preparing and analysing a sample, for example a suspension, comprises: a sampling device adapted to sampling a fluid sample, at least one sample preparation unit adapted to prepare the sample, and at least one analysing unit. By adapting the device for sampling and analysing a sample for placement in direct vicinity to a process pipe and adapting the sampling device to sample a fluid sample directly from a gate, a compact and cost-efficient device is provides, which also provides fast feedback to a process to be controlled.

Abstract translation: 用于对样品（例如悬浮液）进行取样，制备和分析的装置包括：适于对流体样品进行取样的采样装置，适于制备样品的至少一个样品制备单元和至少一个分析单元。 通过使设备采样和分析样品以直接放置在过程管道附近，并使采样设备直接从浇口采样流体样品，提供了一种紧凑且经济高效的设备，这也提供了快速反馈 一个被控制的过程。

公开(公告)号：EP2860152B1

公开(公告)日：2017-03-22

申请号：EP14182597.6

申请日：2014-08-28

Applicant: Tsung, Cheng-Sheng

Inventor： Tsung, Cheng-Sheng ,  Chuang, Shih-Hao

IPC: B81C1/00 ,  G02B5/00

CPC classification number: H01L33/44 ,  B81C1/00031 ,  B81C2201/0149 ,  G01N21/01 ,  G01N2201/02 ,  G02B5/008 ,  H01L33/60 ,  H01L2933/0058

Abstract: A method for fabricating a microstructure to generate surface plasmon waves comprises steps of: (S1) preparing a substrate (10), and (S2) using a carrier material (22) to carry a plurality of metallic nanoparticles (21) and letting the metallic nanoparticles (21) undertake self-assembly to form a microstructure on the substrate (10), wherein the metallic nanoparticles (21) are separated from each other or partially agglomerated to allow the microstructure to be formed with a discontinuous surface. The present invention fabricates the microstructure having the discontinuous surface by a self-assembly method to generate the surface plasmon waves, thus exempts from using the expensive chemical vapor deposition (CVD) technology and is able to reduce the time and cost of fabrication. The present invention also breaks the structural limitation on generation of surface plasmon waves to enhance the effect of generating the surface plasmon waves.

Abstract translation: 一种用于制造微结构，以产生表面等离子体激元波的方法包括以下步骤：使用载体材料（22）来进行金属纳米粒子（21）的多个部分并加以让金属制备底物（10）和（S2）（S1） 纳米颗粒（21）进行自我组装以形成在基板（10），worin金属纳米粒子（21）彼此分离或部分聚集，以允许微结构具有不连续表面上形成微观结构。 本发明编造具有由自组装方法来产生表面等离子体波的不连续表面的微观结构，因此，从使用昂贵的化学气相沉积（CVD）技术的免并且能够减少时间和制造成本。 因此，本发明打破上产生表面等离激元波的结构限制，以提高生成的表面等离子体激元波的影响。

公开(公告)号：EP2878952A4

公开(公告)日：2016-05-25

申请号：EP13823350

申请日：2013-07-08

Applicant: HITACHI HIGH TECH CORP

Inventor： IIJIMA MASAHIKO ,  MAKINO AKIHISA ,  ANDO MANABU

IPC: G01N35/00 ,  G01N1/38 ,  G01N21/47 ,  G01N21/59 ,  G01N21/75 ,  G01N35/02 ,  G01N35/04

CPC classification number: G01N21/75 ,  G01N1/38 ,  G01N21/47 ,  G01N21/59 ,  G01N35/00603 ,  G01N2035/0446 ,  G01N2201/02 ,  G01N2201/061 ,  G01N2201/12

Abstract: An automatic analyzer which can reduce the effort necessary for conducting a test of limit of detection/limit of quantification properties and managing the test results is provided. Operation condition-setting means for conducting an evaluation test for at least one of a limit of detection and a limit of quantification for each measurement item, determination condition-setting means for setting a determination condition of the evaluation test, and a calculation unit for obtaining a measurement result of a dilution series containing different dilution concentrations by controlling the sample-dispensing mechanism, the reagent-dispensing mechanism and the measurement unit based on the set operation condition, and calculating a test result of the evaluation test from the measurement result of the dilution series based on the set determination condition are disposed.

公开(公告)号：EP2972209A1

公开(公告)日：2016-01-20

申请号：EP14721665.9

申请日：2014-03-14

Applicant: Beckman Coulter, Inc.

Inventor： GRAHAM, Marshall Donnie ,  GRAHAM, William Gerry ,  CLARKIN, James P. ,  WELLS, Mark A. ,  CANO, Jose M. ,  ARBOLEDA, Carlos Alberto ,  SANCHEZ, Armando J.

IPC: G01N15/14 ,  C03B23/047

CPC classification number: G01N21/05 ,  C03B23/047 ,  C03C27/00 ,  G01N15/1434 ,  G01N2015/1006 ,  G01N2015/1452 ,  G01N2015/1486 ,  G01N2015/149 ,  G01N2201/02 ,  Y02P40/57

Abstract: An improved optical flow cell adapted for use in a flow cytometer for differentiating formed bodies (e.g., blood cells) in liquid suspensions. Preferably manufactured by assembling, aligning, and optically joining at least two elements made from transparent material, the improved flow cell has a seamless internal flow channel of preferably non-circular cross-section in a cylindrical first element through which prepared samples can be metered and an independent second element having an external envelope suited to acquisition of optical parameters from formed bodies in such suspensions, the second element being conforming and alignable to the first element so that non-axisymmetric refractive effects on optical characterizing parameters of formed bodies passing through the flow channel in the first element may be minimized before the two elements are optically joined and fixed in working spatial relationship.

Abstract translation: 改进的光学流通池适用于流式细胞仪，用于分离液体悬浮液中的成形体（例如血细胞）。 优选地，通过组装，对准和光学地连接由透明材料制成的至少两个元件制造，改进的流动池具有在圆柱形第一元件中优选非圆形横截面的无缝内部流动通道，通过该圆形第一元件可以计量准备的样品， 独立的第二元件具有适合于在这种悬架中从成形体获取光学参数的外部包络线，第二元件与第一元件一致并对准，使得对通过流动的成形体的光学特性参数的非轴对称折射效应 在两个元件以工作空间关系被光学连接和固定之前，第一元件中的通道可以被最小化。

公开(公告)号：EP2929320A1

公开(公告)日：2015-10-14

申请号：EP13827005.3

申请日：2013-12-05

Applicant: Radisens Diagnostic Limited

Inventor： CURTIN, Damian

IPC: G01N21/07 ,  G01N21/64 ,  G01N33/53 ,  G01N33/58

CPC classification number: G01N33/542 ,  G01N21/07 ,  G01N21/64 ,  G01N21/6428 ,  G01N33/53 ,  G01N33/5432 ,  G01N33/582 ,  G01N2021/6439 ,  G01N2021/6441 ,  G01N2201/02

Abstract: The invention relates to a microfluidic system and method of processing biological samples in microfluidic system comprising the steps of the steps of positioning at least one detection chamber adapted for receiving particles, said particles comprising a reference label and reporter label, wherein the labels exhibit different wavelength properties when irradiated with light; and normalising the particle reporter label by using any detected magnitude in the measured properties of the reference label.

公开(公告)号：EP2926115A1

公开(公告)日：2015-10-07

申请号：EP13858774.6

申请日：2013-12-02

Applicant: The University Of North Carolina At Chapel Hill

Inventor： SUPERFINE, Richard ,  OBERHARDT, Bruce, J. ,  SPERO, Richard, Chasen ,  FALVO, Michael, Richard ,  FISER, Briana, Lee ,  TAYLOR, Russell, Morton ,  JUDITH, Robert Michael

IPC: G01N21/17 ,  G01N33/483

CPC classification number: G01N21/47 ,  G01N21/59 ,  G01N21/82 ,  G01N27/22 ,  G01N27/72 ,  G01N33/49 ,  G01N33/4905 ,  G01N2021/825 ,  G01N2201/02 ,  G01N2201/062

Abstract: Methods, systems, and computer readable media for determining physical properties of a specimen in a portable point of care device are disclosed. According to one aspect, a method includes placing a specimen onto an active surface that includes a plurality of microposts extending outwards from a substrate, wherein each micropost includes a proximal end attached to the substrate and a distal end opposite the proximal end and generating an actuation force in proximity to the micropost array that compels at least some of the microposts to exhibit motion. The method further includes detecting light that is emitted by an illumination source and interacts with the active surface while the at least some microposts exhibit motion in response to the actuation force, measuring data that represents the detected light interacting with the active surface, and determining at least one physical property of the specimen based on the measured data.

公开(公告)号：EP2889905A1

公开(公告)日：2015-07-01

申请号：EP14200076.9

申请日：2014-12-23

Applicant: Nichia Corporation

Inventor： Amari, Koichi

IPC: H01L25/075

CPC classification number: G01N21/25 ,  G01N21/8806 ,  G01N2201/02 ,  G01N2201/062 ,  H01L25/0753 ,  H01L33/486 ,  H01L33/50 ,  H01L33/54 ,  H01L33/62 ,  H01L2224/16225 ,  H01L2924/0002 ,  H01L2933/0041 ,  H01L2933/0066 ,  H01L2924/00

Abstract: An aggregate board, comprising: an insulator having a front face and a rear face; a pair of a first front face wiring pattern and a second front face wiring pattern, a plurality of which are arranged on the front face of the insulator; a pair of a first rear face wiring pattern and a second rear face wiring pattern, a plurality of which are arranged on the rear face of the insulator; at least one first inner layer wiring pattern that is separated from the second front face wiring pattern and the second rear face wiring pattern, that is connected to the first front face wiring pattern and the first rear face wiring pattern, and that extends in a first direction in an interior of the insulator; at least one second inner layer wiring pattern that is separated from the first front face wiring pattern and the first rear face wiring pattern, that is connected to the second front face wiring pattern and the second rear face wiring pattern, and that has a part that extends in a second direction which is different from the first direction, in the interior of the insulator; and the first inner layer wiring pattern and the second inner layer wiring pattern being positioned in the same layer.

Abstract translation: 一种聚集板，包括：具有前表面和后表面的绝缘体; 一对第一前面布线图案和第二前面布线图案，多个布置在绝缘体的正面上; 一对第一背面布线图案和第二背面布线图案，多个布置在绝缘体的背面上; 至少一个第一内层布线图案，其与第二正面布线图案和第二背面布线图案分离，连接到第一正面布线图案和第一背面布线图案，并且在第一前面布线图案 方向在绝缘体的内部; 与第一正面布线图案和第一背面布线图案分离的至少一个第二内层布线图案，其连接到第二正面布线图案和第二背面布线图案，并且具有 在绝缘体的内部沿与第一方向不同的第二方向延伸; 并且第一内层布线图案和第二内层布线图案位于同一层中。

公开(公告)号：EP2881726A1

公开(公告)日：2015-06-10

申请号：EP13825500.5

申请日：2013-07-05

Applicant: Ushio Denki Kabushiki Kaisha ,  Kyushu University, National University Corporation

Inventor： OKI, Yuji ,  YOSHIOKA, Hiroaki ,  MORITA, Kinichi

IPC: G01N21/64

CPC classification number: G01N21/645 ,  G01N21/6402 ,  G01N27/44721 ,  G01N33/0057 ,  G01N2201/02 ,  G01N2201/0221 ,  G01N2201/06113

Abstract: Provided is a small and easy-to-carry light-induced fluorescence measuring device capable of minimizing alignment displacements in an optical system due to impact and so forth, suppressing reflected light and scattered light and so forth from entering a fluorescence measuring unit, and capable of carrying out fast and high-performance measurements. A laser light source (1) for emitting excitation light, a sample case (2), a photomultiplier tube (4) constituting the fluorescence measuring unit, a fluorescence collecting optical system (3) and so forth are embedded in a resin material (6) that is transparent to the excitation light and the light including fluorescence emitted from a sample (S). The resin material (6) is provided in at least part of a light path that guides the fluorescence in the fluorescence collecting optical system (3), and this resin forms a housing that holds the laser light source (1), the fluorescence collecting optical system (3), the photomultiplier (4) and so forth. A pigment having wavelength characteristics for absorbing the excitation light, Raman light generated from the resin, and so forth is contained substantially in a uniform manner in a resin region (61) that surrounds the light path through which the excitation light and the light including the fluorescence pass, so as to absorb all these types of light travelling outside the light path.

Abstract translation: 本发明提供一种能够使由于冲击等引起的光学系统中的对准位移最小化并容易携带的光诱导荧光测定装置，抑制反射光和散射光等进入荧光测定单元，能够 进行快速和高性能的测量。 将用于发射激发光的激光光源（1），样品盒（2），构成荧光测量单元的光电倍增管（4），荧光收集光学系统（3）等嵌入树脂材料 ）对于激发光是透明的，包括从样品（S）发出的荧光的光。 树脂材料（6）设置在引导荧光收集光学系统（3）中的荧光的光路的至少一部分中，并且该树脂形成保持激光光源（1）的壳体，荧光收集光学 系统（3），光电倍增管（4）等。 具有用于吸收激发光的波长特性的颜料，由树脂产生的拉曼光等等基本上均匀地包含在围绕光路的树脂区域（61）中，激发光和包括 荧光通过，以吸收行进在光路外的所有这些类型的光。