Abstract:
A system and method are described herein for self-referencing a sensor that is used to detect a biomolecular binding event and/or kinetics which occur in a sample solution flowing along side a reference solution in a micron-sized deep flow channel.
Abstract:
A system is provided that includes a light-emitting diode (LED); a temperature sensor in thermal contact with the LED and capable of measuring an operating temperature and generating an operating temperature signal; and a temperature regulating system capable of receiving the operating temperature signal and regulating the operating temperature based on the operating temperature signal. A method for stabilizing the temperature of an LED is provided. A method is provided that includes providing a system comprising an LED, a reaction region, and a sample in the reaction region; generating excitation beams with the LED; directing excitation beams to the sample; detecting an optical property of the sample to obtain detection data; measuring the- operating temperature of the light emitting diode; and adjusting the detection data of an excitation beam characteristic shift related to the operating temperature, when the LED is operated at the operating temperature to generate the excitation beams.
Abstract:
A defect inspecting apparatus of the invention solves a problem that in a defect inspecting apparatus, because of improving detection sensitivity of a microscopic defect by reducing a detection pixel size, a focal depth becomes shallow, a height of imaging is varied due to environmental change and the detection sensitivity of a defect becomes unstable. This apparatus comprises an XY stage, which carries a substrate to be inspected and scans in a predetermined direction, and a mechanism having a system of irradiating a defect on the inspected substrate at a slant and detecting the defect by a detection optical system disposed on the upper side, which corrects a height of imaging in real time for change in temperature and barometric pressure in order to keep the imaging in a best condition.
Abstract:
A defect inspecting apparatus of the invention solves a problem that in a defect inspecting apparatus, because of improving detection sensitivity of a microscopic defect by reducing a detection pixel size, a focal depth becomes shallow, a height of imaging is varied due to environmental change and the detection sensitivity of a defect becomes unstable. This apparatus comprises an XY stage, which carries a substrate to be inspected and scans in a predetermined direction, and a mechanism having a system of irradiating a defect on the inspected substrate at a slant and detecting the defect by a detection optical system disposed on the upper side, which corrects a height of imaging in real time for change in temperature and barometric pressure in order to keep the imaging in a best condition.
Abstract:
Methods and optical systems for scanning of a target sample, including methods and systems using a low mass scan head and methods and systems for conducting a scanned optically transduced assay where the scanning includes at least one first relative angular motion and at least one second angular motion or at least one linear motion. The present invention also relates to methods and systems for performing sample assays, and for producing and measuring optical responses and signatures.
Abstract:
An apparatus and non-invasive method of measuring oxygen by exciting a luminescent compound disposed in a container and then measuring the intensity of the light emitted by the excited luminescent compound as it relaxes to the ground state. A plot of emission intensity as a function of time results in an exponential decay curve the area of which is inversely proportional to the oxygen concentration. The oxygen concentration can be determined over a wide temperature range by measuring the temperature of the container and the emission intensity and then applying the following equation: [O2]=(ATa(T)2+BTa(T)+CTa)(tau)2+(ATb(T)2+BTb(T)+CTb)(tau)+(ATc(T)2+BTc(T)+CTc) T is the measured temperature; tau is the area of the exponential decay curve; and ATa, BTa, CTa, ATb, BTb, CTb, ATc, BTc, and CTc are coefficients that are specific to the luminescent compound being examined.
Abstract translation:一种通过激发设置在容器中的发光化合物测量氧的装置和非侵入性方法,然后测量由激发的发光化合物在其弛豫到基态时发射的光的强度。 作为时间的函数的发射强度的图形导致指数衰减曲线,其面积与氧浓度成反比。 通过测量容器的温度和发射强度可以在较宽的温度范围内确定氧浓度,然后应用以下等式:<?in-line-formula description =“In-line formula”end =“lead”? (T)2 + B Ta(T)+ C < (T a)Ta(T)2(+)Tb(T)&lt;&lt;&lt; (T)+ C Tb(T)T(T)+(C)T(T) (T)+ C T> P> u>在线公式描述=“在线公式”end =“tail”?> T是测量温度; tau是指数衰减曲线的面积; 和Ta,Ta,Ta,Ta,Ta,Tb,Tb,Tb, C Tb,C Tc,B Tc和C Tc是对发光化合物特异的系数 被检查
Abstract:
The present invention relates to a gas sensor arrangement comprising at least one radiation source emitting radiation, a gas measuring chamber which may be filled with a gaseous analyte containing at least one analyte to be measured, and comprising at least one detector device which detects the radiation and generates an output signal indicating the presence and/or the concentration of the analyte. In order to provide an improved gas sensor arrangement of the type mentioned at the outset which ensures, in a particularly simple manner, long-term stable operation of the arrangement even over long periods of time, the control device comprises a power detection unit which may be operated to measure the electrical output consumed by the at least one radiation source.
Abstract:
A non-invasive emitter-photodiode sensor which is able to provide a data-stream corresponding to the actual wavelength of light emitted thereby allowing calibration of the sensor signal processing equipment and resulting in accurate measurements over a wider variation in emitter wavelength ranges.
Abstract:
A method and electronic arrangement for measuring errors with the aid of a gas sensor wherein a plurality of measurement valves occurring instantly during mutual sequential measuring cycles are detected. The electronic circuit arrangement has a plurality of circuit arrangements for compensating measurement errors wherein the measurements are affect with a gas sensor.
Abstract:
Methods and optical systems for scanning of a target sample, including methods and systems using a low mass scan head. The present invention also relates to methods and systems for performing sample assays, and for producing and measuring optical responses and signatures.