Abstract:
PURPOSE: A composition containing Astraglus membranaceus extract is provided to prevent acne pigmentation and/or scar and to be used in cosmetic, food, or medial field. CONSTITUTION: A composition for suppressing acne pigmentation contains Astraglus membranaceus extract as an active ingredient. The Astraglus membranaceus extract suppresses gelatinase. The composition is used in the form of cosmetic product. A composition for aftercare of acne contains Astraglus membranaceus extract as an active ingredient. A food additive or health food contains Astraglus membranaceus extract.
Abstract:
PURPOSE: A composition containing valproic acid for promoting hair growth or preventing hair loss is provided to apply in pharmaceutical and cosmetic field. CONSTITUTION: A composition for preventing hair loss or promoting hair growth contains valproic acid or pharmaceutically acceptable salt thereof as an active ingredient. The salt is sodium valproate. The composition is manufactured in a percutaneous administration. The composition is also manufactured hypodermic injection or external use formulation. A pharmaceutical or cosmetic composition contains the composition for preventing hair loss or promoting hair growth.
Abstract:
A sphingosylphosphorylcholine(SPC) antagonist is provided to prevent and treat diseases related to the expression decrease of anti-bacterial peptide such as atopic dermatitis, and screen the SPC antagonist by analyzing the expression recover of gene or protein of the anti-bacterial peptide. The sphingosylphosphorylcholine(SPC) antagonist manufactures the medicine for restoring the expression of anti-bacterial peptide back to the normal level in mammal requiring the expression restoration of anti-bacterial peptide. The screening method of the sphingosylphosphorylcholine(SPC) antagonist comprises the steps of: treating the object with sphingosylphosphorylcholine or its derivative to inhibit expression of anti-bacterial peptide; and treating the object with the SPC antagonist candidate material, and analyzing the expression restoration level of the anti-bacterial peptide in the object.
Abstract:
A hexosamine derivative is provided to show excellent intra-abdominal fibrinous adhesion inhibitory activity, thereby being usefully used for preventing or treating post-operative adhesion. A pharmaceutical composition for preventing or treating post-operative adhesion such as intra-abdominal fibrinous adhesion comprises a hexosamine compound represented by a formula(1) or a pharmaceutically acceptable salt thereof as an active ingredient, wherein the active ingredient is selected from the group consisting of galactosamine, D-(+)-glucosamine hydrochloride, and D-(+)-galactosamine hydrochloride.
Abstract:
본 발명은 생강, 건강, 오수유 및 초두구로 이루어진 군으로부터 선택된 하나 이상의 추출물을 유효성분으로 함유하는 조성물에 관한 것으로서, 구체적으로 본 발명의 추출물은 뛰어난 가려움증 억제 효과를 나타내어, 염증성 피부염, 아토피성 피부염 등으로부터 유발되는 가려움증의 억제 및 완화용 조성물로 유용하게 이용될 수 있다. 생강, 건강, 오수유, 초두구, 가려움증, 소양증, 피부 외용제
Abstract:
본명세서에는, 피부세포분화촉진용조성물과피부세포분화촉진물질의스크리닝방법이개시된다. 본발명의피부세포분화촉진용조성물은 JAB-1의발현또는활성을억제하고, 그결과서라이어신의세포핵내로의이동을억제하여, 피부세포분화를효과적으로촉진할수 있다. 따라서, 상기조성물은피부보습, 피부장벽기능강화또는아토피완화치료에효과적이다, 또한, 일측면에따른피부세포분화촉진물질스크리닝방법은, 각질형성세포에시험물질을처리하고 JAB-1의상대적발현정도를확인함으로써, 간편하고신속하며효율적으로각질세포분화촉진물질을스크리닝할수 있다.