MELT-STABILIZED ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE AND METHOD OF MAKING THE SAME
    122.
    发明申请
    MELT-STABILIZED ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE AND METHOD OF MAKING THE SAME 审中-公开
    熔融超稳定超高分子量聚乙烯及其制备方法

    公开(公告)号:US20170015794A1

    公开(公告)日:2017-01-19

    申请号:US15124454

    申请日:2015-02-26

    Applicant: ZIMMER, INC.

    Inventor: Dirk Pletcher

    Abstract: Various embodiments disclosed relate to melt-stabilized materials including ultra high molecular weight polyethylene (UHMWPE), methods of making the same, and medical implants including the same. In various embodiments, the present invention provides a method of melt-stabilizing a material including UHMWPE. The method includes obtaining or providing a solid material including UHMWPE including a first concentration of free-radicals. The method includes coating at least part of the solid material with a liquid composition including at least one antioxidant, to provide a coated solid material. The method includes heating the coated solid material in an environment including oxygen, the heating being sufficient to melt at least part of the UHMWPE, to provide a heated material. The method also includes solidifying the heated material, to provide a melt-stabilized material including UHMWPE including a second concentration of free-radicals, wherein the second concentration of free-radicals is less than the first concentration of free-radicals.

    Abstract translation: 所公开的各种实施方案涉及包括超高分子量聚乙烯(UHMWPE)的熔融稳定材料,其制备方法和包括其的医用植入物。 在各种实施方案中,本发明提供了熔融稳定包含UHMWPE的材料的方法。 该方法包括获得或提供包括UHMWPE的固体材料,其包括第一浓度的自由基。 该方法包括用包含至少一种抗氧化剂的液体组合物涂覆至少部分固体材料,以提供涂覆的固体材料。 该方法包括在包括氧的环境中加热涂覆的固体材料,加热足以熔化至少部分UHMWPE,以提供加热的材料。 该方法还包括固化加热的材料,以提供包含UHMWPE的熔融稳定材料,其包括第二浓度的自由基,其中第二浓度的自由基小于第一浓度的自由基。

    System for solidification of liquid medical waste
    125.
    发明授权
    System for solidification of liquid medical waste 有权
    液体医疗废物固化系统

    公开(公告)号:US08821363B1

    公开(公告)日:2014-09-02

    申请号:US13670562

    申请日:2012-11-07

    Applicant: Quint Barefoot

    Inventor: Quint Barefoot

    CPC classification number: A62D3/33 A61L2/23 B01J20/28016 B09B3/00 C08K2201/013

    Abstract: The invention includes a system for solidification of liquid medical waste for use in connection with a vessel configured to receive an aqueous liquid to be solidified. The system includes an absorbent composition including a plurality of surface cross-linked superabsorbent particles and a plurality of second particles. Additionally, a soluble packet may be included so that the absorbent composition is released upon dissolution of the packet. The invention also includes a liquid solidification system for reducing gel block and a method of solidifying liquid medical waste.

    Abstract translation: 本发明包括用于与配置成接收待固化的水性液体的容器结合使用的液体医疗废物的固化系统。 该系统包括吸收组合物,其包括多个表面交联的超吸收颗粒和多个第二颗粒。 此外,可以包括可溶性包装,使得吸收性组合物在包装溶解时释放。 本发明还包括用于还原凝胶块的液体凝固系统和固化液体医疗废物的方法。

    Hybrid superparamagnetic iron oxide nanoparticles and polyethylenimine as a magnetoplex for gene transfection
    127.
    发明授权
    Hybrid superparamagnetic iron oxide nanoparticles and polyethylenimine as a magnetoplex for gene transfection 有权
    混合超顺磁性氧化铁纳米颗粒和聚乙烯亚胺作为基质转染的磁复合物

    公开(公告)号:US08445025B2

    公开(公告)日:2013-05-21

    申请号:US13074491

    申请日:2011-03-29

    Abstract: Disclosed are the nanoparticle and the method for the same, and the preparing method includes steps of mixing polyethylenimine (PEI) with the poly(acrylic acid)-bound iron oxide (PAAIO) to form a PEI-PAAIO polyelectrolyte complex (PEC) and mixing the PEI-PAAIO PEC with genetic material such as plasmid DNA to form the PEI-PAAIO/pDNA magnetic nanoparticle. The PEI-PAAIO/pDNA magnetoplex is highly water dispersible and suitable for long term storage, shows superparamagnetism, low cytotoxicity, high stability and nice transfection efficiency, and thus the PEI-PAAIO PEC can replace PEI as a non-viral gene vector.

    Abstract translation: 公开了纳米颗粒及其制备方法,其制备方法包括将聚乙烯亚胺(PEI)与聚(丙烯酸)键合的氧化铁(PAAIO)混合以形成PEI-PAAIO聚电解质络合物(PEC)和混合 PEI-PAAIO PEC与遗传物质如质粒DNA形成PEI-PAAIO / pDNA磁性纳米颗粒。 PEI-PAAIO / pDNA磁复合物具有高水分散性,适合长期保存,显示出超顺磁性,低细胞毒性,高稳定性和良好的转染效率,因此PEI-PAAIO PEC可代替PEI作为非病毒基因载体。

    Ethylene-vinyl alcohol copolymer composition, and powdery coating composition comprising it
    129.
    发明授权
    Ethylene-vinyl alcohol copolymer composition, and powdery coating composition comprising it 有权
    乙烯 - 乙烯醇共聚物组合物和包含它的粉末涂料组合物

    公开(公告)号:US07754331B2

    公开(公告)日:2010-07-13

    申请号:US12503182

    申请日:2009-07-15

    Applicant: Osamu Kazeto

    Inventor: Osamu Kazeto

    Abstract: An ethylene-vinyl alcohol copolymer (EVOH) composition comprises 100 parts by weight of a powder (A) having a particle size of from 22 to 850 μm of an ethylene-vinyl alcohol copolymer (a) which has an ethylene content of from 2 to 60 mol % and has a degree of saponification greater than 95%, and from 0.0001 to 2 parts by weight of inorganic particles (B) having primary particles with a mean particle size of from 1 to 100 nm. The EVOH powder coating composition of the present invention forms a coating film having good uniformity when applied to a substrate as powder coating, even when it contains 1 part by weight or more water relative to 100 parts by weight of EVOH resin.

    Abstract translation: 乙烯 - 乙烯醇共聚物(EVOH)组合物包含100重量份的乙烯 - 乙烯醇共聚物(a)的粒径为22〜850μm的粉末(A),其乙烯含量为2〜 60摩尔%,皂化度大于95%,和0.0001〜2重量份具有平均粒径为1〜100nm的一次粒子的无机粒子(B)。 本发明的EVOH粉末涂料组合物即使当相对于100重量份的EVOH树脂含有1重量份以上的水分时,也可以形成作为粉末涂料涂布在基材上的均匀性均匀的涂膜。

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