Abstract:
A method for detecting a target analyte associated with nano-sized gold- and /or silver- containing detecting labels in a microarray of samples, wherein the labels indicate presence or absence of a target analyte in a sample, comprises (i) sequentially illuminating at least two sample groups with at least two different monochromatic lights, said sample groups including (a) a first sample group containing at least one sample potentially containing the target analyte, and (b) a second sample group serving as positive control or negative control, (ii) detecting intensity of light reflected, absorbed or emitted from each of said sample groups when illuminated with each of the monochromatic lights, (iii) recording groups of values associated with the light intensity reflected, absorbed or emitted from the sample groups, with each group of values associated with each of the monochromatic lights for each of the sample groups, (iv) comparing the groups of values associated with said sample groups and each of said monochromatic lights; and (v) determining the presence or absence of the target analyte based on the comparison in step (iv), wherein said monochromatic lights include at least a blue monochromatic light or a monochromatic light with a frequency in the range of 10nm to 100nm. Apparatus for performing such method is also disclosed.
Abstract:
A gas detector (10) that is arranged to sense the concentration levels of target gases oxygen, methane, carbon monoxide, and hydrogen sulphide, within a gas sample from an environment surrounding the detector. The gas detector (10) comprises laser sources (12a-12d) that are arranged to transmit radiation through the gas sample at four target wavelengths that correspond approximately to the optimum absorption wavelengths of each of the target gases and an optical detector (16) that is arranged to sense the intensity of the radiation transmitted through the gas sample at each of the target wavelengths. A control system (22) generates representative concentration level information for the target gases based on the level of absorption of the radiation transmitted.
Abstract:
A gas detector (10) that is arranged to sense the concentration levels of target gases oxygen, methane, carbon monoxide, and hydrogen sulphide, within a gas sample from an environment surrounding the detector. The gas detector (10) comprises laser sources (12a-12d) that are arranged to transmit radiation through the gas sample at four target wavelengths that correspond approximately to the optimum absorption wavelengths of each of the target gases and an optical detector (16) that is arranged to sense the intensity of the radiation transmitted through the gas sample at each of the target wavelengths. A control system (22) generates representative concentration level information for the target gases based on the level of absorption of the radiation transmitted.
Abstract in simplified Chinese:本发明之一实施例为提供一种于样本微数组中侦测具有含奈米尺寸金-及/或银-侦测标记物之目标分析物之方法,该标记物会指示出样本中目标分析物之存在与否,包含(i)依序使用至少二不同单色光照射至少二样本组,该样本组包括(a)第一样本组,包含至少一可能含有该目标分析物之样本,以及(b)第二样本组,作为阳性对照组或阴性对照组,(ii)侦测每一样本反射、吸收或发出之光线强度,当以每一单色光照射时,(iii)记录与该样本组反射、吸收或发出之光相关之数值组,或与每一样本组之每一单色光相关之数值组,(iv)将该样本组与每一单色光相关之数值组互相比较;以及(v)以步骤(iv)之比较为基础,决定该目标分析物是否存在,其中该单色光包括至少蓝光单色光或具有频率范围10nm至1000nm之单色光。