122.
    发明专利
    未知

    公开(公告)号:BRPI0804506A2

    公开(公告)日:2011-08-30

    申请号:BRPI0804506

    申请日:2008-02-20

    Inventor: FROST JOHN W

    Abstract: Catalytic processes for preparing caprolactam, pipecolinic acid, and their derivatives, from lysine or alpha-amino-epsilon-caprolactam starting materials, and products produced thereby. A process for preparing caprolactam or a derivative thereof, the process comprising contacting a reactant comprising lysine or alpha aminocaprolactam with a catalyst and a gas comprising hydrogen gas, in the presence of a solvent. The catalyst may be provided on a support material, such as a transition metal.

    123.
    发明专利
    未知

    公开(公告)号:NO330989B1

    公开(公告)日:2011-08-29

    申请号:NO20053910

    申请日:2005-08-22

    Applicant: UCB FARCHIM SA

    Abstract: The present invention relates to new enantiomerically pure piperazine derivatives of formula (I) wherein Y represents hydroxy or a leaving group and n is 1, 2, 3, 4 or 5, and to their use as synthesis intermediates, especially for the preparation of pharmaceutically active compounds

    способ получения капролактама путем добавления циклoгексаноноксима к реакционной смеси

    公开(公告)号:UA86770C2

    公开(公告)日:2009-05-25

    申请号:UAA200512449

    申请日:2004-05-17

    Abstract: Изобретениекасаетсяспособаполучениякапролактамапутемдобавленияциклoгексаноноксимак реакционнойсмеси, котораясодержиткапролактами сернуюкислоту, спомощьюсмесительногоустройства, причемсмесительноеустройствовключает (і) трубопровод, черезкоторыйпротекаетреакционнаясмесь, и (іі) каналы, которыерасположенывокругтрубопроводаи открытыв трубопровод, ауказанныйспособвключаетпропусканиереакционнойсмесичерезтрубопроводи подачуциклогексаноноксимав реакционнуюсмесьчерезодинилибольшеизуказанныхканалов, где Re>5000, причем Re означаетчислоРейнольдса, определенноекак, где= плотность (вкг/м) реакционнойсмеси, �

    129.
    发明专利
    未知

    公开(公告)号:DE69829867T2

    公开(公告)日:2006-02-23

    申请号:DE69829867

    申请日:1998-09-10

    Abstract: PCT No. PCT/IL98/00440 Sec. 371 Date May 11, 2000 Sec. 102(e) Date May 11, 2000 PCT Filed Sep. 10, 1998 PCT Pub. No. WO99/12900 PCT Pub. Date Mar. 18, 19992,3-Dioxabicyclo[3.3.1]nonane derivatives, carrying, at position 4, a sulfur-containing functionality selected from the group consisting of sulfonyl, sulfinyl and sulfenyl, adhered to C(4) vie methylene group, represented by structural formula (A) wherein: X is hydrogen, hydroxy, alkoxy, optionally substituted by alkoxy or acyloxy, aralkoxy optionally substituted by alkoxy or aryloxy, and M is hydrogen, hydroxy, alkoxy, alkenyloxy, acyloxy, optionally substituted by acyl or acyloxy, aralokoxy, arylalkenyloxy, oxalyloxy substituted by alkoxy, di(alkyl)amino or alkyl(aryl)amino, di(aralalkyl)amino or carbonyloxy substituted by arloxy, di(alkyl)amino, di(aralkyl)amino and alkyl(aryl)amino; or X and M together represent a carbon-carbon bond or an oxygen atom; L is hydrogen or L and M together represent a carbon-carbon bond; and either Z is a radical R-S(=O)n- and Y is hydrogen, or Y is R-S(=O)n- and Z is hydrogen, wherein R is alkyl optionally substituted by alkoxy or alkoxycarbonyl, cycloalkyl, or aryl or araklkyl optionally substituted by alkyl, halogen or CF3; and n is 0, 1, or 2, are useful for the prevention and/or treatment of malaria.

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