-
1.发明申请AMIDOMETHYL-SUBSTITUTED 2-(4-SULFONILAMINO)-3-HIDROXY-3,4-DIHYDRO-2H-CHROMIUM-6-YL-DERIVATIVES AND DRUGS CONTAINING SAID COMPOUNDS 审中-公开酰氨基甲基取代的2-（4- SULFONILAMINO）-3- HIDROXY -3,4-二氢-2H-色烯-6-基衍生物，制备方法和中间体FOR THEIR及药物含有这些化合物的
公开(公告)号：WO2005037780A2
公开(公告)日：2005-04-28
申请号：PCT/EP2004052539
申请日：2004-10-14
Applicant: SOLVAY PHARM GMBH
Inventor： SYKES DAVID , MOLONEY BRIAN , MARRISON LESTER , ZIEGLER DIETER , MLINARIC MICHAEL , BOECKER CHRISTIANE , BRUECKNER REINHARD , WESKE MICHAEL , WITTE KLAUS , FISCHER YVAN
IPC: A61K31/353 , C07D311/68 , C07D407/12 , C07D
CPC classification number: C07D407/12 , C07D311/68
Abstract: The invention relates to compounds of general formula (I), wherein the meaning of R , R , R , R , R and R is given in a description, to a method for producing said compounds and to intermediate products thereof. Drugs containing the inventive compounds of formula (1) are also disclosed.
Abstract translation: 有通式（I）的化合物，其中，R <1>，R <2>，R <3>，R <4>，R <5>和R <6>具有在说明书中给出，以及一个的含义 一种用于这些化合物并描述这个过程的中间产物的制备方法。 此外，可以给出含有它们的式（I）的药物组合物的化合物。
-
公开(公告)号：BRPI0610559A2
公开(公告)日：2010-06-29
申请号：BRPI0610559
申请日：2006-04-11
Applicant: SOLVAY PHARM GMBH
Inventor： MOLONEY BRIAN , MARRISON LESTER , ZIEGLER DIETER , MLINARIC MICHAEL , BOECKER CHRISTIANE , WESKE MICHAEL , WITTE KLAUS , FISCHER YVAN , BRUECKNER REINHARD
IPC: C07D311/68 , A61K31/353 , A61K31/4025 , A61K31/453 , A61K31/497 , A61K31/5355 , A61P9/00 , C07D405/12 , C07D413/12
Abstract: Cardiovascular active compounds of the general formula (I), wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 and n have the meanings given in the description, and also a process for the preparation of these compounds and intermediate products of this process are described. Furthermore, pharmaceutical compositions comprising the compounds of Formula (I) are specified.
-
公开(公告)号：PL1678130T3
公开(公告)日：2009-01-30
申请号：PL04817204
申请日：2004-10-14
Applicant: SOLVAY PHARM GMBH
Inventor： SYKES DAVID , MOLONEY BRIAN , MARRISON LESTER , ZIEGLER DIETER , MLINARIC MICHAEL , BOECKER CHRISTIANE , BRUECKNER REINHARD , WESKE MICHAEL , WITTE KLAUS , FISCHER YVAN
IPC: C07D201/00 , A61K31/353 , C07D311/68 , C07D407/12
-
公开(公告)号：DK1678130T3
公开(公告)日：2008-12-01
申请号：DK04817204
申请日：2004-10-14
Applicant: SOLVAY PHARM GMBH
Inventor： SYKES DAVID , MOLONEY BRIAN , MARRISON LESTER , ZIEGLER DIETER , MLINARIC MICHAEL , BOECKER CHRISTIANE , BRUECKNER REINHARD , WESKE MICHAEL , WITTE KLAUS , FISCHER YVAN
IPC: C07D201/00 , A61K31/353 , C07D311/68 , C07D407/12
Abstract: The invention relates to compounds of general formula (I), wherein the meaning of R 1 , R 2 , R 3 , R 4 , R 5 and R 6 is given in a description, to a method for producing said compounds and to intermediate products thereof. Drugs containing the inventive compounds of formula (1) are also disclosed.
-
公开(公告)号：ES2313126T3
公开(公告)日：2009-03-01
申请号：ES04817204
申请日：2004-10-14
Applicant: SOLVAY PHARM GMBH
Inventor： SYKES DAVID , MOLONEY BRIAN , MARRISON LESTER , ZIEGLER DIETER , MLINARIC MICHAEL , BOECKER CHRISTIANE
IPC: C07D201/00 , A61K31/353 , C07D311/68 , C07D407/12
Abstract: Compuestos de la fórmula general I, (Ver fórmula) en donde, R 1 significa alquilo C1 - 4, R 2 significa alquilo C1 - 4, R 3 significa fenilo, que está eventualmente sustituido, 1-2 veces, con halógeno, alquilo C1 - 4, alcoxi C1 - 4 o trifluorometilo; naftilo o bifenilo, R 4 significa hidrógeno; alquilo C1 - 6 o cicloalquil C3 - 7-alquilo C1 - 4, R 5 significa hidrógeno y R 6 significa alquilo C1 - 6; fenil-alquilo C1 - 4, cuyo grupo fenilo está eventualmente sustituido 1 vez con halógeno; furil-alquilo C1 - 4 o tetrahidronaftilo, o R 5 y R 6 , junto con el nitrógeno al que están unidos, forman un anillo de piperazina el cual está eventualmente sustituido con fenilo.
-
Patent Agency Ranking
公开(公告)号：HK1116167A1
公开(公告)日：2008-12-19
申请号：HK08105447
申请日：2008-05-16
Applicant: SOLVAY PHARM GMBH
Inventor： MOLONEY BRIAN , MARRISON LESTER , ZIEGLER DIETER , MLINARIC MICHAEL , BOECKER CHRISTIANE , WESKE MICHAEL , WITTE KLAUS , FISCHER YVAN , BRUECKNER REINHARD
IPC: A61K20060101 , A61P20060101 , C07D20060101
Abstract: Cardiovascular active compounds of the general formula (I), wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 and n have the meanings given in the description, and also a process for the preparation of these compounds and intermediate products of this process are described. Furthermore, pharmaceutical compositions comprising the compounds of Formula (I) are specified.
-
公开(公告)号：AT405547T
公开(公告)日：2008-09-15
申请号：AT04817204
申请日：2004-10-14
Applicant: SOLVAY PHARM GMBH
Inventor： SYKES DAVID , MOLONEY BRIAN , MARRISON LESTER , ZIEGLER DIETER , MLINARIC MICHAEL , BOECKER CHRISTIANE , BRUECKNER REINHARD , WESKE MICHAEL , WITTE KLAUS , FISCHER YVAN
IPC: C07D201/00 , A61K31/353 , C07D311/68 , C07D407/12
Abstract: The invention relates to compounds of general formula (I), wherein the meaning of R 1 , R 2 , R 3 , R 4 , R 5 and R 6 is given in a description, to a method for producing said compounds and to intermediate products thereof. Drugs containing the inventive compounds of formula (1) are also disclosed.
-
公开(公告)号：NO20075766A
公开(公告)日：2007-11-09
申请号：NO20075766
申请日：2007-11-09
Applicant: SOLVAY PHARM GMBH
Inventor： ZIEGLER DIETER , WESKE MICHAEL , FISCHER YVAN , MOLONEY BRIAN , MARRISON LESTER , MLINARIC MICHAEL , BOECKER CHRISTIANE , BRUECKNER REINHARD , WITTE KLAUS
IPC: C07D311/68 , C07D405/12
CPC classification number: C07D311/68 , C07D405/12 , C07D413/12
-
公开(公告)号：AU2004281195A1
公开(公告)日：2005-04-28
申请号：AU2004281195
申请日：2004-10-14
Applicant: SOLVAY PHARM GMBH
Inventor： MOLONEY BRIAN , WESKE MICHAEL , SYKES DAVID , FISCHER YVAN , MLINARIC MICHAEL , BOECKER CHRISTIANE , BRUECKNER REINHARD , WITTE KLAUS , MARRISON LESTER , ZIEGLER DIETER
IPC: A61K31/353 , C07D311/68 , C07D407/12
Abstract: The invention relates to compounds of general formula (I), wherein the meaning of R 1 , R 2 , R 3 , R 4 , R 5 and R 6 is given in a description, to a method for producing said compounds and to intermediate products thereof. Drugs containing the inventive compounds of formula (1) are also disclosed.
-
公开(公告)号：UA96734C2
公开(公告)日：2011-12-12
申请号：UAA200712393
申请日：2006-04-11
Applicant: SOLVAY PHARM GMBH
Inventor： MOLONEY BRIAN , MARRISON LESTER , CYGLER DITER , MLINARIC MICHAEL , BOECKER CHRISTIANE , WESKE MICHAEL , WITTE KLAUS , FISCHER YVAN , BRUCKNER RAINHARD
IPC: C07D311/68 , A61K31/353 , A61K31/4025 , A61K31/497 , A61K31/5355 , A61P9/00 , C07D405/12 , C07D413/12
Abstract: Взаявкеописанысоединенияобщейформулы I, (I)вкоторой R, R, R, R, R, R, R, R, R, Rи n имеютзначения, указанныев описании, которыеимеютсердечно-сосудистуюактивность, атакжеспособполученияэтихсоединенийи промежуточныепродукты. Крометого, описаныфармацевтическиекомпозиции, которыесодержатсоединенияформулы I.
-
-
-
-
-
-
-
-
-
Search Results
27
records
(took 0.023 seconds)
