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    IMPACT INSTRUMENT
    131.
    发明申请
    IMPACT INSTRUMENT 审中-公开
    影响仪器

    公开(公告)号：WO1998017442A1

    公开(公告)日：1998-04-30

    申请号：PCT/US1997018661

    申请日：1997-10-16

    Applicant: BOARD OF REGENTS/UNIVERSITY OF TEXAS SYSTEM

    Inventor： BOARD OF REGENTS/UNIVERSITY OF TEXAS SYSTEM ,  SCHRODER, Kurt, A.

    IPC: B25G01/01

    CPC classification number: A63B49/08 ,  A63B53/14 ,  A63B60/00 ,  A63B60/06 ,  A63B60/08 ,  A63B60/10 ,  A63B60/12 ,  A63B60/54 ,  A63B2102/02 ,  A63B2102/32 ,  B25D1/00 ,  B25D1/04 ,  B25G1/01

    Abstract: An impact instrument (200) for delivering an impulse to an object. The impact instrument (200) may include an impact surface (202) for contacting the object and an elongated member (204) extending from the impact surface (202) that terminates in an end. The elongated member (204) may include a grasping region in the vicinity of the end. When the instrument is grasped within the grasping region, the center of percussion of the instrument preferably coincides with the impact surface (202). The instrument may also contain pivoting grasping member disposed on the elongated member. A cavity (212, 214, 216, 218, 220) is preferably formed between the grasping member (206) and the elongated member (204) and may contain compressible material. The grasping member (206) may rigidly contact the elongated member (204) at an ideal pivot point (208). The grasping member (206) is preferably adapted to pivot with respect to the elongated member (204) at the ideal pivot point (208). The pivoting of the grasping member (206) preferably increases the amount of impulse delivered to an object, decreases vibration experienced by the user of the instrument, and reduces counter-rotational forces imparted from the instrument to the user. The impact instrument (200) may be a hammer, ax, golf club, tennis racket, or similar device.

    Abstract translation: 一种用于将冲击传递到物体的冲击仪器（200）。 冲击仪器（200）可以包括用于接触物体的冲击表面（202）和从终止于终端的冲击表面（202）延伸的细长构件（204）。 细长构件（204）可以包括在端部附近的抓握区域。 当把持器被夹持在抓握区域内时，仪器的冲击中心优选地与冲击表面（202）重合。 仪器还可以包括设置在细长构件上的枢转抓握构件。 空腔（212,214,216,218,220）优选地形成在抓握构件（206）和细长构件（204）之间，并且可以包含可压缩材料。 抓握构件（206）可以在理想枢转点（208）处与细长构件（204）刚性接触。 抓握构件（206）优选地适于在理想枢转点（208）处相对于细长构件（204）枢转。 抓握构件（206）的枢转优选地增加输送到物体的冲击量，降低仪器用户所经历的振动，并减少从仪器向用户施加的反向旋转力。 冲击仪器（200）可以是锤子，斧头，高尔夫球杆，网球拍或类似装置。

    INHIBITORS OF DUAL LEUCINE ZIPER (DLK) KINASE FOR THE TREATMENT OF DISEASE
    134.
    发明申请
    INHIBITORS OF DUAL LEUCINE ZIPER (DLK) KINASE FOR THE TREATMENT OF DISEASE 审中-公开
    双亮氨酸拉链（DLK）激酶抑制剂用于治疗疾病

    公开(公告)号：WO2018044808A1

    公开(公告)日：2018-03-08

    申请号：PCT/US2017/048941

    申请日：2017-08-28

    Applicant: BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM

    Inventor： SOTH, Michael, J. ,  JONES, Philip ,  RAY, James ,  LIU, Gang ,  LE, Kang ,  CROSS, Jason

    IPC: A61K31/44 ,  A61K31/4178 ,  C07D401/04

    Abstract: Disclosed herein are compounds which inhibit the kinase activity of dual leucine zipper (DLK) kinase (MAP3K12), pharmaceutical compositions, and methods of treatment of DLK-mediated diseases, such as neurological diseases that result from traumatic injury to central nervous system and peripheral nervous system neurons (e.g. stroke, traumatic brain injury, spinal cord injury), or that result from a chronic neurodegenerative condition (e.g. Alzheimer's disease, frontotemporal dementia, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, spinocerebellar ataxia, progressive supranuclear palsy, Lewy body disease, Kennedy's disease, and other related conditions), from neuropathies resulting from neurological damage (chemotherapy -induced peripheral neuropathy, diabetic neuropathy, and related conditions) and from cognitive disorders caused by pharmacological intervention (e.g. chemotherapy induced cognitive disorder, also known as chemobrain).

    Abstract translation: 本文公开了抑制双亮氨酸拉链（DLK）激酶（MAP3K12）的激酶活性的化合物，药物组合物以及治疗DLK介导的疾病例如由创伤引起的神经疾病的方法 中枢神经系统和外周神经系统神经元损伤（例如中风，创伤性脑损伤，脊髓损伤）或由慢性神经变性疾病（例如阿尔茨海默氏病，额颞叶痴呆，帕金森病，亨廷顿病，肌萎缩侧索硬化，脊髓小脑 共济失调，进行性核上性麻痹，路易体疾病，肯尼迪氏病和其它相关病症），神经病损伤（化学疗法诱导的周围神经病，糖尿病性神经病和相关病症）和由药理学干预（例如化学疗法 诱导认知障碍，也称为化学细胞）。

    NANO/MICRO SCALE POROUS STRUCTURED ALLOYS USING SELECTIVE ALLOYING PROCESS BASED ON ELEMENTAL POWDERS
    135.
    发明申请
    NANO/MICRO SCALE POROUS STRUCTURED ALLOYS USING SELECTIVE ALLOYING PROCESS BASED ON ELEMENTAL POWDERS 审中-公开
    纳米/微米级多孔结构合金的基于元素粉末的选择性合金化工艺

    公开(公告)号：WO2018017581A1

    公开(公告)日：2018-01-25

    申请号：PCT/US2017/042619

    申请日：2017-07-18

    Applicant: BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM

    Inventor： HU, Yingbin ,  LI, Jianzhi

    IPC: B22F1/00 ,  B22F3/00 ,  B22F3/105

    Abstract: A method of forming titanium boron alloys includes forming a mixture of elemental titanium with elemental boron and heating the mixture with a laser, wherein a power level of the laser is set such that reaction of the elemental titanium with the elemental boron to form a titanium-boron alloy is initiated and self-sustaining.

    Abstract translation: 形成钛硼合金的方法包括形成元素钛与元素硼的混合物并用激光加热该混合物，其中激光的功率水平被设定为使得元素钛与 元素硼形成钛 - 硼合金开始并自我维持。

    BURST-BASED CACHE DEAD BLOCK PREDICTION
    139.
    发明申请
    BURST-BASED CACHE DEAD BLOCK PREDICTION 审中-公开
    基于BURST的缓存死锁预测

    公开(公告)号：WO2011046639A2

    公开(公告)日：2011-04-21

    申请号：PCT/US2010/038406

    申请日：2010-06-11

    Applicant: BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM ,  BURGER, Doug ,  LIU, Haiming

    Inventor： BURGER, Doug ,  LIU, Haiming

    IPC: G06F12/08 ,  G06F12/00

    CPC classification number: G06F12/0879

    Abstract: The present disclosure generally relates to cache memory systems and/or techniques to identify dead cache blocks in cache memory systems. Example systems may include a cache memory that is accessible by a cache client. The cache memory may include a plurality of storage locations for a first cache block, with a most recently used position location in the cache memory. A cache controller may be configured to predict whether the first cache block stored in the cache memory is identified as a dead cache block based on a cache burst of the first cache block. The cache burst may comprise a first access of the first cache block by a cache client and any subsequent contiguous accesses of the first cache block following the first access by the cache client while the first cache block is in a most recently used position of the cache set.

    Abstract translation: 本公开通常涉及用于识别高速缓冲存储器系统中的死缓存块的高速缓存存储器系统和/或技术。 示例系统可以包括可由缓存客户端访问的高速缓存存储器。 高速缓冲存储器可以包括用于第一高速缓存块的多个存储位置，其中最近使用的位置位置在高速缓冲存储器中。 高速缓存控制器可以被配置为基于第一高速缓存块的高速缓存突发来预测存储在高速缓冲存储器中的第一高速缓存块是否被识别为死区高速缓存块。 高速缓存突发可以包括由高速缓存客户端进行的第一高速缓存块的第一次访问以及第一高速缓存块处于高速缓存的最近使用位置之后由缓存客户机进行第一次访问之后的第一高速缓存块的任何后续连续访问 组。

    SCALABLE BUS-BASED ON-CHIP INTERCONNECTION NETWORKS
    140.
    发明申请
    SCALABLE BUS-BASED ON-CHIP INTERCONNECTION NETWORKS 审中-公开
    基于总线的片上互连网络

    公开(公告)号：WO2010147855A1

    公开(公告)日：2010-12-23

    申请号：PCT/US2010/038320

    申请日：2010-06-11

    Applicant: BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM ,  KECKLER, Stephen, W. ,  GROT, Boris

    Inventor： KECKLER, Stephen, W. ,  GROT, Boris

    IPC: H04W40/24 ,  G06F13/00

    CPC classification number: G06F15/7825

    Abstract: The present disclosure generally relates to systems for routing data across a multinodal network. Example systems include a multinodal array having a plurality of nodes and a plurality of physical communication channels connecting the nodes. At least one of the physical communication channels may be configured to route data from a first node to two or more other destination nodes of the plurality of nodes. The present disclosure also generally relates to methods for routing data across a multinodal network and computer accessible mediums having stored thereon computer executable instructions for performing techniques for routing data across a multinodal network.

    Abstract translation: 本公开通常涉及用于在多节点网络上路由数据的系统。 示例系统包括具有多个节点的多节点阵列和连接节点的多个物理通信信道。 物理通信信道中的至少一个可以被配置为将数据从第一节点路由到多个节点中的两个或更多个其他目的地节点。 本公开还通常涉及用于跨越多节点网络路由数据的方法以及其上存储有用于执行跨越多节点网络路由数据的技术的计算机可执行指令的计算机可访问介质。

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