Improvements in the production of aromatic aminosulphonyl-amidines

    公开(公告)号:GB827446A

    公开(公告)日:1960-02-03

    申请号:GB1486558

    申请日:1958-05-09

    Applicant: BASF AG

    Abstract: The invention comprises sulphonamides having, in one tautomeric form, the general formula wherein Ar is an aromatic radical such as a phenyl or naphthyl radical optionally bearing substituents, for example alkyl, aryl, aralkyl, cycloalkyl, alkoxy, nitro or halogen substituents, and n is an integer from 3 to 7, and their preparation by treating an amino substituted aromatic sulphonamide with an O-alkyl ether of a lactam, preferably in an indifferent medium in the presence of a tertiary amine catalyst. The compounds are used as pesticides, medicaments and azo dye components. In examples: (1) sulphanilamide is treated with butyrolactim-O-methyl ether to give 2-sulphanilamido - D 1 - pyrroline; (2) 3 - amino - 4-methoxy benzenesulphonamide is treated with caprolactim to give 2-(31-amino-41-methoxy-benzenesulphonamido) - D 1 - tetrahydroazepine; by similar methods there are prepared 2-sulphanilamido -, 2 - (21 - methyl - 51 - methoxy-sulphanilamido) -, 2 - (21 : 51 - dimethoxy - sulphanilamido) -, 2 - (21 - amino - 51 - nitro - benzenesulphonamido) -, 2 - (31 - amino - 41 chlorobenzenesulphonamido) - and 2 - (21 - amino-naphthalene - 61 - sulphonamido) -, a D 1 - tetrahydro-azepine and 2-sulphanilamido- D 1-tetrahydropyridine.

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