公开(公告)号：WO99023474A1

公开(公告)日：1999-05-14

申请号：PCT/EP1998/006468

申请日：1998-10-12

IPC: G01J3/457 ,  B01L3/00 ,  G01N21/03 ,  G01N21/25 ,  G01N21/27 ,  G01N21/64 ,  G01N37/00 ,  G02B21/00 ,  G02B21/16 ,  G02B21/36

CPC classification number: G01N21/6452 ,  B01L3/5085 ,  B01L2300/0829 ,  G01N21/253 ,  G01N21/6456 ,  G01N2201/024

Abstract: An optical system made up of lens arrays (2i, 7) and normal lenses (41, 5, 42) is particularly suitable for use as a massive parallel reader (approx. 10 channels) for micro titer plates (1) and the like in absorption, fluorescence and luminescence.

Abstract translation: 包括透镜阵列的光学系统（2 1，7）和正常透镜（41，5,42）是特别适合作为大规模并行（大约10 <2>信道）读取器用于微量滴定板（1）和在吸收，荧光和发光等。

公开(公告)号：WO99009393A1

公开(公告)日：1999-02-25

申请号：PCT/DE1998/002307

申请日：1998-08-11

IPC: G01N21/64 ,  G01J3/28 ,  G01J3/44 ,  G01J3/457 ,  G01N21/03

CPC classification number: G01J3/457 ,  G01J3/4406 ,  G01J2003/2866

Abstract: According to the disclosed process, light rays enter the transparent medium in a parallel direction and are deflected inside the transparent medium towards a focus, thus avoiding the use of refractive optics. The disclosed focusing optics enable light rays of different wavelengths to be bundled onto a point within the sample, considerably simplifying the design and adjustment of a polychromatic florescence correlation spectroscopy device.

Abstract translation: 在该方法中，光束入射在平行进入透明介质和所述透明介质内被偏转到一个焦点回来。 这允许避免使用折射光学系统的。 根据本发明的聚焦光学系统允许不同波长的光束的捆扎在样品内的点。 这简化了结构和多色荧光相关光谱设备的调整是大大简化。

公开(公告)号：US12232846B2

公开(公告)日：2025-02-25

申请号：US18134805

申请日：2023-04-14

Applicant: The Trustees of Columbia University in the City of New York

Inventor： Elizabeth Marjorie Clare Hillman ,  Sean A. Burgess

IPC: A61B5/00 ,  G01J3/28 ,  G01J3/42 ,  G01J3/457 ,  G02B23/24 ,  G02B26/10

Abstract: Optical imaging or spectroscopy described can use laminar optical tomography (LOT), diffuse correlation spectroscopy (DCS), or the like. An incident beam is scanned across a target. An orthogonal or oblique optical response can be obtained, such as concurrently at different distances from the incident beam. The optical response from multiple incident wavelengths can be concurrently obtained by dispersing the response wavelengths in a direction orthogonal to the response distances from the incident beam. Temporal correlation can be measured, from which flow and other parameters can be computed. An optical conduit can enable endoscopic or laparoscopic imaging or spectroscopy of internal target locations. An articulating arm can communicate the light for performing the LOT, DCS, or the like. The imaging can find use for skin cancer diagnosis, such as distinguishing lentigo maligna (LM) from lentigo maligna melanoma (LMM).

公开(公告)号：US12130136B2

公开(公告)日：2024-10-29

申请号：US17707479

申请日：2022-03-29

Applicant: Thorlabs, Inc.

Inventor： Oliver Heckl ,  Jakob Fellinger

IPC: G01S17/34 ,  G01B9/02001 ,  G01J3/433 ,  G01J3/45 ,  G01J3/457 ,  G01S7/48 ,  G01S7/497 ,  G01S17/894 ,  G01J3/28 ,  G01J3/42

CPC classification number: G01B9/02008 ,  G01J3/433 ,  G01J3/45 ,  G01J3/457 ,  G01S7/4808 ,  G01S7/497 ,  G01S17/34 ,  G01S17/894 ,  G01J2003/2879 ,  G01J2003/423 ,  G01J2003/4332

Abstract: A device that uses two intensity modulated frequency combs to measure distances with high precision and high data acquisition rate without any moving parts and without length ambiguity that is inherent conventional ranging based on two frequency combs. A modulation signal having a repetition rate identical to the repetition rate difference between the two combs is used to do a direct time-of-flight length measurement, hence avoiding the given length ambiguity while harvesting the increased precision of the dual-comb approach.

公开(公告)号：US20230307562A1

公开(公告)日：2023-09-28

申请号：US18023418

申请日：2021-05-26

Applicant: HAMAMATSU PHOTONICS K.K.

Inventor： Tatsuo DOUGAKIUCHI ,  Akio ITO ,  Masahiro HITAKA ,  Tadataka EDAMURA

IPC: H01L31/0352 ,  G01J3/45 ,  G01J3/457 ,  G01J3/10 ,  H01L23/482 ,  H01L31/02 ,  H01L31/0232 ,  H01L31/0304

CPC classification number: H01L31/035236 ,  G01J3/45 ,  G01J3/457 ,  G01J3/10 ,  H01L23/4821 ,  H01L31/02005 ,  H01L31/02325 ,  H01L31/035281 ,  H01L31/03046 ,  G01J2003/102

Abstract: A photodetector includes: a semiconductor substrate; a mesa portion formed on a major surface of the semiconductor substrate to extend along an optical waveguide direction; a first contact layer; a second contact layer; a first electrode; and an air bridge wiring electrically connected to the first contact layer and the first electrode. When viewed in a direction perpendicular to the major surface of the semiconductor substrate, a length of the mesa portion in the optical waveguide direction is longer than a length of the mesa portion in a direction perpendicular to the optical waveguide direction. The air bridge wiring is led out from the first contact layer to one side in the direction perpendicular to the optical waveguide direction, and is bridged between the first contact layer and the first electrode.

公开(公告)号：US11579095B2

公开(公告)日：2023-02-14

申请号：US17723044

申请日：2022-04-18

Applicant: SAAM, Inc.

Inventor： John Coates

IPC: G01N21/85 ,  G01N21/25 ,  G01J3/00 ,  G01J3/02 ,  G01J3/36 ,  G01J3/42 ,  G01J3/457 ,  G01N21/359

Abstract: A remote sampling sensor for determining characteristics of a sample includes measurement optics and an insertion probe. The measurement optics are configured to emit light and detect returned light. The insertion probe includes a chamber, the chamber being configured to permit the sample to enter the chamber, an insertion tip at a distal end of the insertion probe, and a retro-reflective optic adjacent the insertion tip. The retro-reflective optic is configured to return the light from the measurement optics through the chamber to the measurement optics. The insertion probe is configured to be remotely located from the measurement optics.

公开(公告)号：US11573125B2

公开(公告)日：2023-02-07

申请号：US16999461

申请日：2020-08-21

Applicant: UNIVERSITY OF WYOMING

Inventor： William D. Rice ,  Subash Kattel ,  Joseph R. Murphy

IPC: G01J3/457 ,  G01J5/10 ,  G01J5/48 ,  G01J1/42

Abstract: Embodiments of the present disclosure generally relate to apparatus for and methods of detecting light utilizing the spin Seebeck effect (SSE). In an embodiment, a method for detecting broadband light is provided. The method includes generating a SSE in a device by illuminating the device with light, the device comprising a bilayer structure disposed over a substrate, the bilayer structure comprising a non-magnetic metal layer and a magnetic insulator layer. The method further includes measuring the SSE based on a field modulation method, determining, based on the measuring, an optically-created thermal gradient of the device, and detecting a wavelength range of the light. Apparatus for detecting broadband light are also described.

公开(公告)号：US20220236191A1

公开(公告)日：2022-07-28

申请号：US17723044

申请日：2022-04-18

Applicant: SAAM, Inc.

Inventor： John Coates

IPC: G01N21/85 ,  G01N21/25 ,  G01J3/00 ,  G01J3/02 ,  G01J3/42 ,  G01J3/457 ,  G01J3/36

Abstract: A remote sampling sensor for determining characteristics of a sample includes measurement optics and an insertion probe. The measurement optics are configured to emit light and detect returned light. The insertion probe includes a chamber, the chamber being configured to permit the sample to enter the chamber, an insertion tip at a distal end of the insertion probe, and a retro-reflective optic adjacent the insertion tip. The retro-reflective optic is configured to return the light from the measurement optics through the chamber to the measurement optics. The insertion probe is configured to be remotely located from the measurement optics.

公开(公告)号：US11255729B2

公开(公告)日：2022-02-22

申请号：US15450483

申请日：2017-03-06

Applicant: SAMSUNG ELECTRONICS CO., LTD.

Inventor： Sang Kon Bae ,  Yun S Park ,  So Young Lee

IPC: G01J3/457 ,  G01J3/28 ,  G01J3/02 ,  G06F17/18

Abstract: An apparatus and method for monitoring a stability of a spectrum are provided. The apparatus for monitoring stability of a spectrum includes a spectroscope configured to measure a spectrum of a sample and a processor configured to calculate a similarity change index of the measured spectrum and to determine the stability of the measured spectrum by analyzing the calculated similarity change index.

公开(公告)号：US20210196155A1

公开(公告)日：2021-07-01

申请号：US17203087

申请日：2021-03-16

Applicant: Rijul GUPTA

Inventor： Rijul GUPTA

IPC: A61B5/1455 ,  A61B5/145 ,  G01J3/00 ,  A61B5/00 ,  G01N21/31 ,  G01N21/47 ,  G01J3/28 ,  G01N21/49 ,  G01J3/02 ,  G01J3/10 ,  G01J3/427 ,  G01J3/457

Abstract: A multi-channel measurement device for measuring properties of human tissue, may comprise a microcontroller and first and second source/sensor complexes. The first source/sensor complex may include a first housing having a first measurement portion, a first light sensor coupled to the microcontroller and exposed to the first measurement portion, and a first plurality of light sources coupled to the microcontroller and exposed to the first measurement portion. The second source/sensor complex may include a second housing having a second measurement portion, a second light sensor coupled to the microcontroller and exposed to the second measurement portion, and a second plurality of light sources coupled to the microcontroller and exposed to the second measurement portion. The first and second source/sensor complexes are coupled to each other such that the first measurement portion is opposite the second measurement portion and human tissue may be placed between the the first and second measurement portions. The microprocessor is configured with instructions stored in non-volatile memory to individually activate each of the light sources of the first and second pluralities of light sources and to record light intensity detected by the first and second light sources while an individual light source is activated. Each combination of an individually activated light source and one of the first and second light sensors provides a distinct measurement channel for measuring the absorption spectra of human blood and tissue.