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公开(公告)号：KR1020080105470A
公开(公告)日：2008-12-04
申请号：KR1020070053097
申请日：2007-05-31
Applicant: (주)아모레퍼시픽
CPC classification number: A23L1/3002 , A23L33/105 , A23V2002/00 , A61K8/97 , A61K36/258 , A61K2800/522 , A61Q19/02 , A61Q19/08 , A23V2250/2124 , A23V2200/318 , A23V2200/332
Abstract: A food composition is provided to prevent and improve obesity by enhancing the expression of CPT-1 gene limiting the velocity in the oxidation of fat and by promoting the degradation of fat. A food composition for preventing obesity contains an extract of the fruit of insam (ginseng) as an active ingredient. Preferably the food composition expresses the Carnitine Palmitoyl Transferase-1 (CPT-1) gene. Preferably the extract of the fruit of insam is obtained by common extraction method.
Abstract translation: 提供食物组合物，通过增强CPT-1基因的表达来限制脂肪氧化速度和促进脂肪降解来预防和改善肥胖。 用于预防肥胖的食物组合物含有作为活性成分的insam（人参）的果实的提取物。 优选地，食物组合物表达肉碱棕榈酰转移酶-1（CPT-1）基因。 优选通过普通提取方法获得insam的果实提取物。
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公开(公告)号：KR1020080104600A
公开(公告)日：2008-12-03
申请号：KR1020070051593
申请日：2007-05-28
Applicant: (주)아모레퍼시픽
IPC: A61K36/258 , A61P9/10 , A61P19/02
CPC classification number: A61K36/258 , A23L33/105 , A23V2002/00 , A61K9/0019 , A61K9/0095 , A61K9/1652 , A61K9/2018 , A61K9/4875 , A61K31/198 , A23V2250/2124 , A23V2200/318 , A23V2200/326 , A61K2300/00
Abstract: A composition for promoting the blood circulation is provided to promote the blood circulation by expanding the blood vessel and to inhibit the aging of the blood vessel. A composition for promoting the blood circulation contains an extract of the fruit of insam (ginseng) as an effective ingredient. Preferably the extract of the fruit of insam is prepared by adding ethanol to the dried one of insam fruit to reflux it for extraction, and filtering and concentrating the obtained extract; and removing the oil-soluble component, adding butanol to it to extract it, and concentrating the obtained extract.
Abstract translation: 提供促进血液循环的组合物，以通过扩张血管来促进血液循环，并抑制血管的老化。 用于促进血液循环的组合物含有作为有效成分的insam（人参）水果的提取物。 优选地，通过将乙醇加入到干燥的塞米果中以回流以提取来制备insam果实的提取物，并过滤并浓缩所得提取物; 除去油溶性成分，向其中加入丁醇进行萃取，浓缩得到的提取物。
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Patent Agency Ranking
公开(公告)号：KR1020080100145A
公开(公告)日：2008-11-14
申请号：KR1020080043488
申请日：2008-05-09
Applicant: (주)아모레퍼시픽
IPC: A61K36/258 , A61K31/195 , A61P15/10
CPC classification number: A61K36/258 , A23L33/105 , A23V2250/0606 , A61K2236/331
Abstract: A composition for ameliorating male sexual function is provided to increase erection of penis by containing ginseng fruit extract and an L-arginine as an active ingredient and increasing production of nitrogen oxide(NO). A composition for ameliorating male sexual function comprises 0.01~100 weight% of ginseng fruit extract as an active ingredient. An L-arginine is additionally included in the active ingredient. The composition is used as refinement, pilule, single active ingredient preparation, capsule, granule, ointments, drink medicine or injection.
Abstract translation: 提供改善男性性功能的组合物，通过含有人参水果提取物和L-精氨酸作为活性成分并增加氮氧化物（NO）的产生来增加阴茎的勃起。 用于改善男性性功能的组合物包含0.01〜100重量％的人参果实提取物作为活性成分。 活性成分中还含有L-精氨酸。 该组合物用作精制，真空，单一活性成分制剂，胶囊，颗粒，软膏，饮料或注射剂。
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公开(公告)号：KR100858059B1
公开(公告)日：2008-09-10
申请号：KR1020060119447
申请日：2006-11-30
Applicant: (주)아모레퍼시픽
Abstract: 본 발명은 레몬 과피로부터 산, 알칼리, 효소반응을 통해 디오스메틴(diosmetin)을 제조하는 방법과 이를 유효성분으로 함유하는 화장료 조성물에 관한 것으로, 보다 상세하게는 피부기질의 분해에 관련된 자외선에 의한 MMP-1의 생합성을 감소시킴으로써 타입 1 프로콜라겐의 생합성을 촉진시키는 효과가 뛰어난 디오스메틴을 제조하는 방법과 이를 유효성분으로 함유하는 피부 노화 예방 및 주름 개선 효과가 우수한 화장료 조성물에 관한 것이다.
레몬 과피(Lemon peel), 디오스메틴(diosmetin), MMP-1, 노화방지, 주름개선-
145.发明公开
公开(公告)号：KR1020070014672A
公开(公告)日：2007-02-01
申请号：KR1020050069506
申请日：2005-07-29
Applicant: (주)아모레퍼시픽
Abstract: A skin external composition for inhibiting phagocytosis of keratinocytes comprising genistein or daidzein is provided to reduce mobility of melanosomes transferred from melanocytes in keratinocytes by inhibiting phagocytosis of keratinocytes activated by exposure to ultra violet ray without cytotoxicity, so that chloasma, freckles and speckles are treated and prevented. The skin external composition for inhibiting phagocytosis of keratinocytes comprises at least one selected from genistein and daidzein, wherein the amount of genistein or daidzein is 0.0001-10 wt.%; the genistein or daidzein is an isoflavone produced from Leguminosae plants and shows estrogen effects; and the composition is formulated as cream, lotion, ointment, aqueous solution, suspension, dispersion or emulsion.
Abstract translation: 提供了一种用于抑制包含染料木黄酮或黄豆苷原的角质形成细胞吞噬作用的皮肤外用组合物，以通过抑制通过暴露于紫外线而没有细胞毒性活化的角质形成细胞的吞噬作用来降低角质形成细胞中从黑素细胞转移的黑素体的移动性，从而处理黄褐斑，雀斑和斑点 预防。 用于抑制角化细胞吞噬的皮肤外用组合物包含选自染料木黄酮和黄豆苷原中的至少一种，其中染料木黄酮或黄豆苷原的量为0.0001-10重量％; 染料木素或黄豆苷原是由豆科植物产生的异黄酮，显示雌激素作用; 并将组合物配制成霜剂，洗剂，软膏，水溶液，悬浮液，分散体或乳液。
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公开(公告)号：KR101112578B1
公开(公告)日：2012-02-16
申请号：KR1020090064852
申请日：2009-07-16
Applicant: 성균관대학교산학협력단
Abstract: 본 발명은 엑센딘의 비강투여를 위한 약제학적 조성물에 관한 것으로서, 보다 상세하게는, 100Da 이상 2kDa미만의 분자량을 갖는 폴리에틸렌글리콜 또는 이의 유도체로 단일 수식된 천연 또는 재조합 엑센딘과 약물수송담체를 포함하는 엑센딘의 비강투여용 약제학적 조성물 및 이의 제조방법에 관한 것이다.
본 발명에 따른 엑센딘 비강투여용 약제학적 조성물은 약물의 체내 반감기 증가와 면역원성 감소를 달성하고, 비강투여를 통하여 엑센딘의 생체이용률을 현저히 향상시킬 수 있으며, 혈장 글루코스 저하, 위 또는 장 운동의 억제, 위 또는 장 공복의 억제 또는 음식 섭취 억제에 의해 유발되는 질환 및 당뇨병 또는 비만을 포함하는 인슐린의 과다분비에 의해 유발되는 질환의 예방 및 치료제로서 사용될 수 있다.
엑센딘-4, 폴리에틸렌글리콜, 히알루론산, 당뇨, 비만, 인슐린, 비강투여, 나노중합체Abstract translation: 目的：提供用于鼻内施用前列腺素的药物组合物，以改善生物利用度，并治疗由排便或胃移动抑制引起的疾病。 构成：用于鼻内施用前列腺素的药物组合物含有聚乙二醇或作为聚乙二醇衍生物的天然或重组外显子。 前列腺素是exedin 4.聚乙二醇衍生物由化学式1表示。用于预防和治疗糖尿病，肥胖或肠易激综合征的治疗剂含有药物组合物。
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公开(公告)号：KR1020110007362A
公开(公告)日：2011-01-24
申请号：KR1020090064852
申请日：2009-07-16
Applicant: 성균관대학교산학협력단
CPC classification number: A61K47/34 , Y10S514/866 , Y10S514/909
Abstract: PURPOSE: A pharmaceutical composition for the nasal administration of exedin is provided to improve bioavailability and to treat diseases caused by the suppression of bowel movements or gastric mobility. CONSTITUTION: A pharmaceutical composition for the nasal administration of exedin contains polyethylene glycol or natural or recombinant exedin as a derivative of polyethylene glycol. The exedin is exedin 4. The polyethylene glycol derivative is denoted by chemical formula 1. A therapeutic agent for preventing and treating diabetes, obesity or irritable bowel syndrome contains the pharmaceutical composition.
Abstract translation: 目的：提供用于鼻内施用前列腺素的药物组合物，以改善生物利用度，并治疗由排便或胃移动抑制引起的疾病。 构成：用于鼻内施用前列腺素的药物组合物含有聚乙二醇或作为聚乙二醇衍生物的天然或重组外显子。 前列腺素是exedin 4.聚乙二醇衍生物由化学式1表示。用于预防和治疗糖尿病，肥胖或肠易激综合征的治疗剂含有药物组合物。
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