公开(公告)号：US20060121614A1

公开(公告)日：2006-06-08

申请号：US11299784

申请日：2005-12-13

Applicant: Eugene Tokhtuev ,  Anatoly Skirda ,  Viktor Slobodyan ,  Christopher Owen

Inventor： Eugene Tokhtuev ,  Anatoly Skirda ,  Viktor Slobodyan ,  Christopher Owen

IPC: G01N21/93

CPC classification number: G01N21/645 ,  G01N21/15 ,  G01N21/276 ,  G01N21/278 ,  G01N21/6486 ,  G01N21/8507 ,  G01N33/1826 ,  G01N2021/6417 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6478 ,  G01N2201/0218 ,  G01N2201/024 ,  G01N2201/0627 ,  G01N2201/0693 ,  Y10T29/49 ,  Y10T29/49002 ,  Y10T436/108331

Abstract: A multichannel fluorosensor includes an optical module and an electronic module combined in a watertight housing with an underwater connector. The fluorosensor has an integral calibrator for periodical sensitivity validation of the fluorosensor. The optical module has one or several excitation channels and one or several emission channels that use a mutual focusing system. To increase efficiency, the excitation and emission channels each have a micro-collimator made with one or more ball lenses. Each excitation channel has a light emitting diode and an optical filter. Each emission channel has a photodiode with a preamplifier and an optical filter. The electronic module connects directly to the optical module and includes a lock-in amplifier, a power supply and a controller with an A/D converter and a connector. The calibrator provides a response proportional to the excitation intensity, and matches with spectral parameter of fluorescence for the analyzed fluorescent substance.

公开(公告)号：US20050201441A1

公开(公告)日：2005-09-15

申请号：US11011475

申请日：2004-12-14

Applicant: Volker Seyfried ,  Rafael Storz

Inventor： Volker Seyfried ,  Rafael Storz

IPC: H01S3/02 ,  H01S3/09 ,  H01S3/23

CPC classification number: H01S3/02 ,  G01N21/6458 ,  G01N2201/024 ,  G02B21/0032 ,  H01S3/2383

Abstract: A device for generating a laser light beam includes a module. The module includes at least one laser light source, and a mechanical, an electrical and/or an optical interface defined towards an outside of the module.

Abstract translation: 用于产生激光束的装置包括模块。 该模块包括至少一个激光光源，以及朝向模块的外部限定的机械，电和/或光学接口。

公开(公告)号：US20050168741A1

公开(公告)日：2005-08-04

申请号：US10769631

申请日：2004-01-30

Applicant: Rodney Banks

Inventor： Rodney Banks

IPC: G01N21/64

CPC classification number: G01N21/645 ,  G01N33/18 ,  G01N2021/157 ,  G01N2021/6482 ,  G01N2201/0221 ,  G01N2201/024 ,  G01N2201/062 ,  G01N2201/064

Abstract: Described and claimed is an interchangeable tip-open cell fluorometer comprising a housing and a fluorometric probe tip interchangeably connected to the housing, the probe tip including a probe tip housing defining an open cell and enclosing a probe optical arrangement, the probe optical arrangement including an excitation source and a fluorescence detector wherein the excitation source is aimed directly into the fluorescence detector such that a sample can be fluorometrically detected. Also claimed is a method of using this interchangeable tip-open cell fluorometer for detecting fluorescent signals emitted by one or more fluorophores from samples from a natural or industrial water system. The fluorometer, when coupled with a controller, is capable of monitoring and optionally controlling an industrial process or system.

Abstract translation: 描述和要求保护的是可互换的尖端开孔单元荧光计，其包括壳体和可互换地连接到壳体的荧光探针尖端，探针尖端包括限定开放单元并包围探针光学布置的探针尖端壳体，探针光学布置包括 激发源和荧光检测器，其中激发源直接瞄准荧光检测器，使得样品可被荧光测量。 还要求保护的是使用这种可互换的尖端开放式荧光计来从天然或工业水系统的样品中检测由一种或多种荧光团发射的荧光信号的方法。 当与控制器耦合时，荧光计能够监测和可选地控制工业过程或系统。

公开(公告)号：US20040238730A1

公开(公告)日：2004-12-02

申请号：US10477153

申请日：2004-07-12

Inventor： Jorg Langowski ,  Malte Wachsmuth

IPC: H01J003/14

CPC classification number: G01N21/6458 ,  G01N2201/024 ,  G02B21/002

Abstract: A fluorescence fluctuation microscope, in which excitation light and detection light are coupled into or out of a microscope by means of a common beam path, comprises a closed loop scanning unit (22, 23).

Abstract translation: 荧光波动显微镜，其中激发光和检测光通过公共光束路径耦合到显微镜中或离开显微镜，包括闭环扫描单元（22,23）。

公开(公告)号：US06822741B2

公开(公告)日：2004-11-23

申请号：US09947570

申请日：2001-09-07

Applicant: Petri Aronkytö ,  Raimo Harju ,  Asko Myllynpää

Inventor： Petri Aronkytö ,  Raimo Harju ,  Asko Myllynpää

IPC: G01N2125

CPC classification number: G01N21/6452 ,  G01J3/02 ,  G01J3/0275 ,  G01N21/253 ,  G01N2021/6471 ,  G01N2021/6482 ,  G01N2021/6484 ,  G01N2201/024

Abstract: The present invention relates generally to the field of biochemical laboratory. More particularly the invention relates to the improved and more efficient instrumental features of equipment used as e.g. fluorometers, photometers and luminometers. The object of the invention is achieved by providing an optical measurement instrument where there is an interface (218, 223, 233a, 233b, 238) for a changeable optical module (240), the interface being adapted for at least one excitation beam and at least two emission beams. This allows performing various types of measurements by changing an optical module. The change of module and related parameters can be performed automatically controlled by software. It is also possible to easily upgrade the instrument for new types of measurements by just providing the instrument with a new optical module and the related software.

Abstract translation: 本发明一般涉及生化实验室领域。 更具体地，本发明涉及用作例如设备的改进和更有效的器具特征。 荧光计，光度计和光度计。 本发明的目的是通过提供一种光学测量仪器实现的，其中存在用于可变光学模块（240）的界面（218,223,233a，233b，238），所述界面适于至少一个激发光束 最少两个发射光束。 这允许通过改变光学模块执行各种类型的测量。 模块和相关参数的更改可以由软件自动控制。 只需向仪器提供新的光学模块和相关软件，也可以轻松升级仪器进行新型测量。

公开(公告)号：US20030048446A1

公开(公告)日：2003-03-13

申请号：US09947570

申请日：2001-09-07

Inventor： Petri Aronkyto ,  Raimo Harju ,  Asko Myllynpaa

IPC: G01N021/25

CPC classification number: G01N21/6452 ,  G01J3/02 ,  G01J3/0275 ,  G01N21/253 ,  G01N2021/6471 ,  G01N2021/6482 ,  G01N2021/6484 ,  G01N2201/024

Abstract: The present invention relates generally to the field of biochemical laboratory. More particularly the invention relates to the improved and more efficient instrumental features of equipment used as e.g. fluorometers, photometers and luminometers. The object of the invention is achieved by providing an optical measurement instrument where there is an interface (218, 223, 233a, 233b, 238) for a changeable optical module (240), the interface being adapted for at least one excitation beam and at least two emission beams. This allows performing various types of measurements by changing an optical module. The change of module and related parameters can be performed automatically controlled by software. It is also possible to easily upgrade the instrument for new types of measurements by just providing the instrument with a new optical module and the related software.

Abstract translation: 本发明一般涉及生化实验室领域。 更具体地，本发明涉及用作例如设备的改进和更有效的器具特征。 荧光计，光度计和光度计。 本发明的目的是通过提供一种光学测量仪器实现的，其中存在用于可变光学模块（240）的界面（218,223,233a，233b，238），所述界面适于至少一个激发光束 最少两个发射光束。 这允许通过改变光学模块执行各种类型的测量。 模块和相关参数的更改可以由软件自动控制。 只需向仪器提供新的光学模块和相关软件，也可以轻松升级仪器进行新型测量。

公开(公告)号：US20020030894A1

公开(公告)日：2002-03-14

申请号：US09835172

申请日：2001-04-12

Inventor： Martin Volcker ,  Christof Fattinger

IPC: G02B027/10

CPC classification number: G01N21/6452 ,  G01N21/253 ,  G01N2201/024 ,  G02B3/005 ,  G02B3/0068 ,  G02B5/045

Abstract: The invention relates to an imaging system for optical automatic analysers, especially fluorescence readers. On the sample side, the imaging system contains a cylindrical lens array and a prism array, which is arranged upstream of the cylindrical lens array. The prismatic effect of the prisms of the prism array lies in the direction of the cylinder axes of the cylindrical lenses. Together with a telescopic imaging system, the inventive imaging system creates a number of parallel cylindrical focussing volumes between the cylindrical lens array and a detector array, these focussing volumes being slanted towards the optical axis of the telescopic system in relation to the vertical. The arrangement enables the detection of fluorescence with a large aperture in one direction, and at the same time enables depth selective analysis of the fluorescence signal, especially the discrimination of the fluorescent radiation originating from the solution above.

Abstract translation: 本发明涉及一种用于光学自动分析仪，特别是荧光读取器的成像系统。 在样本侧，成像系统包括柱面透镜阵列和棱镜阵列，其布置在柱面透镜阵列的上游。 棱镜阵列的棱镜的棱镜效应位于柱面透镜的圆柱轴线的方向上。 与可伸缩成像系统一起，本发明的成像系统在柱面透镜阵列和检测器阵列之间产生多个平行的圆柱形聚焦体积，这些聚焦体积相对于垂直方向朝伸缩系统的光轴倾斜。 该装置能够在一个方向上检测具有大孔径的荧光，并且同时能够对荧光信号进行深度选择性分析，特别是鉴别源于上述溶液的荧光辐射。

公开(公告)号：US6084680A

公开(公告)日：2000-07-04

申请号：US43323

申请日：1998-03-20

Applicant: Jukka Tuunanen ,  Matti Priha ,  Heikki Tupakka ,  Timo Karmeniemi

Inventor： Jukka Tuunanen ,  Matti Priha ,  Heikki Tupakka ,  Timo Karmeniemi

IPC: G01N21/64 ,  G01N21/03 ,  G01N21/25 ,  G01N21/47 ,  G01N21/01

CPC classification number: G01N21/253 ,  G01N2201/024

Abstract: An optical analyzer measures light directed from a sample to the detector. The apparatus has an optics module which has a detector and optics for directing light emitted by the sample to the detector and which module can be positioned alternatively either so that the light is directed to the detector from above the sample or so that light is directed to the detector from below the sample. The invention is usable in particular in fluorometers and in luminometers.

Abstract translation: PCT No.PCT / FI96 / 00497 Sec。 371日期：1998年3月20日 102（e）1998年3月20日PCT PCT 1996年9月20日PCT公布。 公开号WO97 / 11351 日期1997年3月27日光学分析仪测量从样品导向检测器的光线。 该装置具有光学模块，其具有用于将样品发射的光引导到检测器的检测器和光学器件，并且该模块可以交替地定位，使得光从样品的上方被引导到检测器，或者使得光被引导到 检测器从样品下方。 本发明特别可用于荧光计和发光计。

公开(公告)号：US5420681A

公开(公告)日：1995-05-30

申请号：US101419

申请日：1993-08-03

Applicant: Robert A. Woodruff

Inventor： Robert A. Woodruff

IPC: G01J3/02 ,  G01J3/18 ,  G01J3/28 ,  G01J3/36

CPC classification number: G01J3/2823 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0291 ,  G01J3/0294 ,  G01J3/36 ,  G01J2003/1828 ,  G01N2201/024

Abstract: A multiple spectral imager includes three modular imaging spectrometers, each having a respective collimator, dispersing element, and imaging system. Each collimator includes a pair of parabolic reflectors having a common focal point and an elongated slit positioned at the focal point, and each collimator defines a pupil near the respective dispersing element. The dispersing elements disperse light from various positions along the slit of the collimator into the respective imaging system, and each of the imaging systems includes an array detector that intercepts the dispersed light from the respective dispersing element and registers spectral information in a first direction and spatial information in a second direction. The spectrometers are stacked adjacent to one another, and light from a single directing mirror enters the collimators of all three of the spectrometers. The three array detectors are each responsive to a separate respective spectral region.

Abstract translation: 多光谱成像仪包括三个模块化成像光谱仪，每个具有相应的准直仪，分散元件和成像系统。 每个准直器包括一对抛物面反射器，其具有公共焦点和位于焦点处的细长狭缝，并且每个准直器限定在相应的分散元件附近的光瞳。 分散元件将来自准直仪的狭缝的各种位置的光分散到相应的成像系统中，并且每个成像系统包括阵列检测器，其拦截来自各个分散元件的分散的光，并将光谱信息在第一方向和空间 信息在第二个方向。 光谱仪彼此相邻堆叠，来自单个定向镜的光进入所有三个光谱仪的准直仪。 三个阵列检测器各自响应于单独的相应光谱区域。

公开(公告)号：US5153675A

公开(公告)日：1992-10-06

申请号：US484221

申请日：1990-02-22

Applicant: Kenn A. Beauchaine

Inventor： Kenn A. Beauchaine

IPC: G01J3/453 ,  G02B7/182

CPC classification number: G02B7/1822 ,  G01J3/453 ,  G01N2201/024

Abstract: A modular optical system for a Fourier transform infrared spectrometer which has a baseplate assembly with a baseplate having a top surface and two mirrors mounted to focus at a point above the baseplate. At least two pins extend upwardly from the baseplate top surface and are fixed with respect to the foci of the mirrors. An accessory module has a flat bottomed positioning plate with portions defining pin holes to coincide with the pins of the face plate. A sample holding accessory platform extends from the positioning plate and is fixed with respect to the pin holes so that when the pin holes of the positioning plate are positioned over the pins of the baseplate and the positioning plate bottom surface is engaged with the locator pads on the baseplate, the sample is located at the foci of the mirrors. Three accessory module guides are located on the baseplate having spring-mounted retainer balls accurately spaced a common distance from the surface of the baseplate which engage beveled chamfers in the sides of the positioning plate and hold the accessory module in place. A sample to be analyzed may be placed in the accessory module and positioned in the FTIR spectrometer by hand, requiring no tools to accurately position the sample.

Abstract translation: 一种用于傅里叶变换红外光谱仪的模块化光学系统，其具有底板组件，其具有底板，其具有顶表面和两个安装成在基板上方的点处的两个反射镜。 至少两个销从底板顶表面向上延伸并相对于反射镜的焦点固定。 附件模块具有平底定位板，其具有限定销孔的部分，以与面板的销重合。 样品保持附件平台从定位板延伸并且相对于销孔固定，使得当定位板的销孔定位在基板的销上方并且定位板底表面与定位板接合时 底板，样品位于镜子的焦点。 三个附件模块导向件位于基板上，具有弹簧安装的保持器球，其准确地与基板的表面间隔一定距离，该定位板在定位板的侧面接合斜切倒角并将附件模块固定就位。 要分析的样品可以放置在附件模块中并手动定位在FTIR光谱仪中，不需要任何工具来准确定位样品。