公开(公告)号：WO1993017770A1

公开(公告)日：1993-09-16

申请号：PCT/US1993001569

申请日：1993-02-22

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  GRANT, David, C., H.

IPC: B01D05/00

CPC classification number: B01D5/0054 ,  B01D3/06 ,  B01D5/0051 ,  B01D53/002 ,  B01D53/005 ,  C23G5/04 ,  D06F43/08

Abstract: A system for processing a product with a solvent containing volatile constituents, the system including a pressure chamber (12) for receiving the product, a vacuum pump (18) for evacuating the chamber, a solvent recirculating system for admitting the solvent at a predetermined pressure into the chamber, the solvent recirculating system including a heater (13) for maintaining the temperature of the chamber at the saturation temperature of the solvent, gas liquid separator (34) for separating the gas and liquid components of the solvent discharged from the chamber (12), a first closed loop system connected to the separator to return the gas constituent to the chamber and a second closed loop system connected to the separator to return the liquid component to the chamber.

Abstract translation: 一种用含有挥发性成分的溶剂处理产品的系统，该系统包括用于接收产品的压力室（12），用于抽空该室的真空泵（18），用于以预定压力允许溶剂的溶剂循环系统 溶剂循环系统包括用于将室的温度维持在溶剂的饱和温度的加热器（13），用于分离从室排出的溶剂的气体和液体组分的气液分离器（34） 12），连接到分离器以将气体成分返回到室的第一闭环系统和连接到分离器以将液体组分返回到室的第二闭环系统。

公开(公告)号：WO1993017149A1

公开(公告)日：1993-09-02

申请号：PCT/US1993001570

申请日：1993-02-22

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  GRANT, David, C., H.

IPC: C23G05/02

CPC classification number: B01D5/0054 ,  B01D53/005 ,  C23G5/04

Abstract: A method is provided for cleaning an article with a solvent having a boiling point such that the solvent is a gas at room temperature and one atmosphere pressure. Such a method includes the steps of disposing the article in a chamber, introducing the solvent into the chamber so that the solvent contacts the article, pressurizing the chamber so that the solvent is in a liquid state and removes contaminants from the article, purging the chamber to remove the solvent, and removing the treated article from the chamber. Such a system permits the use of liquids having boiling points lower than room temperature, such as certain C1-C4 halocarbons, which liquids have not previously been used as cleaning solvents.

Abstract translation: 提供一种用具有沸点的溶剂清洗制品的方法，使得溶剂是室温和一个大气压下的气体。 这种方法包括以下步骤：将物品放置在室中，将溶剂引入室中，使得溶剂接触物品，对室进行加压，使得溶剂处于液态并从制品中除去污染物， 以除去溶剂，并从室中除去经处理的物品。 这种系统允许使用沸点低于室温的液体，例如某些C1-C4卤代烃，这些液体以前未被用作清洁溶剂。

公开(公告)号：WO1993017074A1

公开(公告)日：1993-09-02

申请号：PCT/US1993001584

申请日：1993-02-22

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  SIMAN, Jaime, Ernesto ,  LIEBER, Clement ,  SHADFORTH, Nancy

IPC: C08L75/08

CPC classification number: A61L29/049 ,  C08L75/08 ,  A61L29/14 ,  C08L67/00 ,  C08L2666/18

Abstract: Polymer blends having improved torque transmitting properties are disclosed. The polymer blends include polyetherurethane and a concentration of polyetherester sufficient to provide the polymer blend with a 37 DEG C dynamic torque value greater than 40 % of the polymer bland's 25 DEG C dynamic torque value. The polymer blend can be thermally processed to form small diameter tubing suitable for general purpose catheters requiring both a high degree of maneuverability and sufficient resiliency to avoid tissue perforation.

Abstract translation: 公开了具有改善的扭矩传递特性的聚合物共混物。 聚合物共混物包括聚醚聚氨酯和聚醚酯的浓度，足以提供聚合物混合物，其具有大于聚合物混合物25℃动态转矩值的40％的37℃动态力矩值。 聚合物共混物可以被热加工以形成适合通用导管的小直径管道，其需要高度的机动性和足够的弹性以避免组织穿孔。

公开(公告)号：WO1993016406A1

公开(公告)日：1993-08-19

申请号：PCT/US1993001016

申请日：1993-01-28

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  KIM, James ,  MINOT, Mark, M.

IPC: G02B06/28

CPC classification number: A61B5/1459 ,  G02B6/14 ,  G02B6/2808

Abstract: Improved optical mode mixers (52) for use in conjunction with optical fibers (64) and devices incorporating optical fibers are disclosed and claimed. The optical mode mixers (52) are formed from a coherent, orderly bundle of numerous small diameter optical fibers (64) in a longitudinally aligned, parallel array. The mode mixer (52) is optically linked to the fiber optic cable (36) and effectively reduces undesirable high order modes of light transmission while eliminating alignment sensitivity. The coherent fiber optic bundles may be as short as ten wavelengths of light in length and will have a diameter substantially equal to that of the fiber optic cable (36) to which they are coupled.

Abstract translation: 公开并要求保护用于与光纤（64）结合使用的改进的光模式混合器（52）和结合光纤的装置。 光学模式混合器（52）由纵向排列的平行阵列中的许多小直径光纤（64）的相干有序的束形成。 模式混合器（52）光纤连接到光纤电缆（36），并且有效地减少不期望的高阶模式的光透射同时消除对准灵敏度。 相干光纤束的长度可以短至十个波长的光，并且其直径基本上等于与它们耦合的光纤电缆（36）的直径。

公开(公告)号：WO1993011926A2

公开(公告)日：1993-06-24

申请号：PCT/US1992008282

申请日：1992-09-25

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  WOO, Lecon ,  LO, Ying ,  LING, Michael, T., K. ,  LAURIN, Dean ,  GLEASON, Byron ,  BUAN, Lillian, A. ,  JOHNSTON, William, D.

IPC: B29C65/04

CPC classification number: B29C65/04 ,  B29C65/4815 ,  B29C65/52 ,  B29C65/522 ,  B29C65/525 ,  B29C65/526 ,  B29C65/528 ,  B29C66/0044 ,  B29C66/1122 ,  B29C66/24244 ,  B29C66/43 ,  B29C66/472 ,  B29C66/53262 ,  B29C66/71 ,  B29C66/723 ,  B29C66/73143 ,  B29C66/73774 ,  B29C66/7392 ,  B29C66/73921 ,  B29C66/73941 ,  B29C66/81457 ,  B29C66/81871 ,  B29C66/8242 ,  B29C66/8322 ,  B29K2027/06 ,  B29L2031/7148 ,  B65D75/30 ,  Y10T29/49803 ,  Y10T156/1089 ,  Y10T428/1341 ,  Y10T428/1352 ,  Y10T428/31551 ,  Y10T428/31573 ,  Y10T428/31576 ,  Y10T428/31587 ,  Y10T428/31736 ,  Y10T428/31743 ,  Y10T428/31797 ,  Y10T428/3192 ,  B29K2023/04 ,  B29K2023/10 ,  B29K2025/04 ,  B29K2075/00 ,  B29K2067/00 ,  B29K2071/00 ,  B29K2059/00 ,  B29K2023/00 ,  B29K2021/003 ,  B29K2009/06

Abstract: The coating of an RF active material on a non-RF active substrate material of typical thickness for packaging purposes, can generate sufficient thermal energy to effect strong bonding of the substrate materials. The RF active material may be deposited on less than the entire inner surface area of the substrate material, preferably, at or near the portion of the substrate surface which represents the heat seal interface. In this manner of application, additional coating or printing of other substances on the substrate surface can be achieved without hampering the heat sealing process. Flexible medical containers capable of containing a product which is maintained and removed under sterile conditions, can be constructed on commercial production machines from these coated non-RF active substrate materials.

Abstract translation: 在用于包装目的的典型厚度的非RF有源衬底材料上的RF活性材料的涂层可以产生足够的热能来实现衬底材料的强结合。 RF活性材料可以沉积在基板材料的小于整个内表面区域上，优选地沉积在表示热封界面的基板表面的部分处或附近。 以这种施加方式，可以在不影响热封过程的情况下实现在基板表面上的其它物质的附加涂布或印刷。 能够容纳在无菌条件下保持和去除的产品的灵活的医疗容器可以在这些涂覆的非RF活性基底材料的商业生产机器上构建。

公开(公告)号：WO1993009822A1

公开(公告)日：1993-05-27

申请号：PCT/US1992009816

申请日：1992-11-12

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  HARTRANFT, Thomas, P. ,  DUBAUSKAS, Charles, J.

IPC: A61M01/16

CPC classification number: A61M1/1656 ,  A61M1/1664 ,  A61M1/1666

Abstract: An improved conductivity based servo-proportioning system (10, 40) for hemodialysis machines. The servo-proportioning system calculates the actual conductivity contributions of the individual chemical components of the concentrate being utilized, to determine the conductivity set points. An Acidified and Bicarb operation is being performed, then the servo-proportioning system calculates a conductivity set point at both an intermediate and final stage of the servo-proportioning system. If only acetate is being performed, then only the acetate individual chemical components are calculated. If the Na and/or Bicarb concentrations are to be varied, then the conductivity is calculated for the changed Na and/or Bicarb concentrations.

Abstract translation: 用于血液透析机的改进的基于电导率的伺服配比系统（10,40）。 伺服配比系统计算所用浓缩物的各种化学成分的实际电导率贡献，以确定电导率设定点。 正在进行酸化和脱水操作，伺服配比系统在伺服配比系统的中间阶段和最后阶段计算电导率设定点。 如果仅进行乙酸盐，则仅计算乙酸盐单独的化学成分。 如果要改变Na和/或Bicarb浓度，则计算改变的Na和/或Bicarb浓度的电导率。

公开(公告)号：WO1993009775A1

公开(公告)日：1993-05-27

申请号：PCT/US1992009817

申请日：1992-11-12

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  JOHNSON, Douglas, Giles ,  TITUS, Allan, Edward

IPC: A61K31/34

CPC classification number: A61K47/02 ,  A61K9/0019 ,  A61K31/34 ,  A61K47/26

Abstract: A pharmaceutical composition is provided comprising an unbuffered iso-osmotic aqueous formulation containing an effective amount of ranitidine for the treatment of conditions mediated through histamine H2 receptors. The formulation has a pH of greater than or equal to 5.0 and less than 6.5 and preferably includes an osmotic adjusting agent chosen from the group consisting of dextrose and sodium chloride.

公开(公告)号：WO1993007918A1

公开(公告)日：1993-04-29

申请号：PCT/US1992008213

申请日：1992-09-25

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  HOEKWATER, Mark ,  NORDQUIST, Jeffrey, S. ,  FOWLES, Thomas, A. ,  SERTIC, James ,  GORMAN, Brian, J.

IPC: A61M05/00

CPC classification number: A61J1/2089 ,  A61J1/201 ,  A61J1/2051 ,  A61J1/2065 ,  A61M5/1409 ,  Y10S285/921 ,  Y10S604/905

Abstract: A drug delivery device is provided comprising a cartridge body (12) including an upper portion (14) defining a vial receiving area and terminating in a wall (20), the cartridge body (12) including a cannula (22) extending from the wall. A vial (40) including a beneficial agent is coupled by a retaining member (50) to the cartridge body (12) in an inactivated position. The retaining member (50) allows the vial (40) to move to an activated position. The retaining member (50) including an outer member (52) and an inner member (54), the inner member (54) separating from portions of the outer member (52) as the vial (40) moves from the inactivated position to the activated position.

Abstract translation: 提供了药物输送装置，其包括盒主体（12），其包括限定小瓶接收区域并终止于壁（20）的上部部分（14），所述药筒主体（12）包括从壁延伸的套管（22） 。 包括有益剂的小瓶（40）通过保持构件（50）以处于非活动位置的方式与筒体（12）联接。 保持构件（50）允许小瓶（40）移动到激活位置。 包括外部构件（52）和内部构件（54）的保持构件（50），当小瓶（40）从灭活位置移动到内部构件（54）时，内部构件（54）与外部构件（52）的部分分离， 激活位置。

公开(公告)号：WO1993007824A1

公开(公告)日：1993-04-29

申请号：PCT/US1992008785

申请日：1992-10-15

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  DENNEHEY, T., Michael ,  WEST, Joseph, C., Jr. ,  YANG, James, W.

IPC: A61B19/00

CPC classification number: A61B10/025 ,  A61B2010/0258 ,  A61M1/0056

Abstract: A bone marrow collection kit (10) is provided comprising a collection container for receiving a bone marrow containing fluid (12) having a body (14) that defines an interior (16) and an inlet opening (18) and an outlet opening (28) and including a prefilter (30) that extends from the outlet opening (28) into the interior of the collection container (16) so that fluid must flow through the prefilter (30) to exit the collection container (12) through the outlet opening (28). A first inline filter member (50) is coupled to the outlet opening (28) of the collection container (12), the first inline filter member (50) having a flexible plastic body (60) that defines an interior (66), and an inlet opening (68) and an outlet opening (70) and the interior including a filter (72) so constructed and arranged that fluid that enters the inlet opening (68) must flow through the filter (72) to exit the first inline filter member (50) through the outlet opening (70). A container for receiving a resultant filtered bone marror containing fluid (94) having an interior in fluid communication with the outlet opening (70) of the first inline filter member (50) is also provided.

Abstract translation: 提供骨髓收集试剂盒（10），其包括收集容器，用于接收含有液体（12）的骨髓，所述流体具有限定内部（16）和入口开口（18）的主体（14）和出口开口（28） ），并且包括从出口开口（28）延伸到收集容器（16）内部的预过滤器（30），使得流体必须流过预过滤器（30）以通过出口开口离开收集容器（12） （28）。 第一在线过滤器构件（50）联接到收集容器（12）的出口（28），第一在线过滤器构件（50）具有限定内部（66）的柔性塑料体（60），以及 入口开口（68）和出口开口（70），并且内部包括如此构造和布置的过滤器（72），使得进入入口开口（68）的流体必须流过过滤器（72）以离开第一在线过滤器 构件（50）通过出口开口（70）。 还提供了一种用于接收所得过滤的含骨髓液的流体（94）的容器，其具有与第一在线过滤器构件（50）的出口（70）流体连通的内部。

公开(公告)号：WO1993005829A1

公开(公告)日：1993-04-01

申请号：PCT/US1992008212

申请日：1992-09-25

Applicant: BAXTER INTERNATIONAL INC.

Inventor： BAXTER INTERNATIONAL INC. ,  MYREN, Eric ,  CLASSEY, Donald, J. ,  GRAJO, Theresa ,  LYNN, Kenneth ,  MCVEY, John ,  VEHOVSKY, Gabriel

IPC: A61M05/00

CPC classification number: A61M39/281 ,  A61M5/142 ,  A61M5/14228 ,  A61M39/287 ,  A61M2205/60 ,  Y10S128/12

Abstract: The present invention provides an apparatus for use in a peristaltic pump (20) which prevents an inadvertent free flow condition prior to loading or after removal of an I.V. tube (26) in the peristaltic pump (20) and which also prevents the inadvertent occlusion of a loaded I.V. tube (26) in the peristaltic pump (20). A standard I.V. tube (26) has a slide clamp (109) provided thereon. The apparatus includes an I.V. tube groove (29) into which the I.V. tube (26) is positioned, a slide clamp receiving area (62) into which the slide clamp (109) is inserted, and a biased sliding member (81) which the inserted slide clamp (109) engages such that the I.V. tube (26) cannot be loaded into the apparatus without the slide clamp (109) occluding the I.V. tube (26). The present invention also contemplates a slide clamp (109') compatible with the apparatus having a surface pad (125) for facilitating automated identification of the slide clamp (109') in cooperation with a non-obstructive sensor (85) in the safety apparatus.

Abstract translation: 本发明提供一种在蠕动泵（20）中使用的装置，其防止在装载之前或之后除去I.V.之前的无意的自由流动状态。 蠕动泵（20）中的管（26），并且还防止加载的IV的意外闭塞。 管（26）在蠕动泵（20）中。 标准I.V. 管（26）具有设置在其上的滑动夹（109）。 该装置包括I.V. 管槽（29），其中I.V. 管（26）定位，滑动夹具（109）插入其中的滑动夹具接收区域（62）和插入的滑动夹具（109）接合的偏置滑动构件（81），使得I.V。 管（26）不能装载到装置中，而不夹紧I.V的滑动夹具（109）。 管（26）。 本发明还考虑了与具有表面垫（125）的装置兼容的滑动夹具（109'），用于与安全装置中的非阻塞性传感器（85）协作，便于自动识别滑动夹具（109'） 。