Abstract:
A measuring apparatus (200) is provided for inspecting a seal (50) of an item (20). The measuring apparatus (200) includes a radiation source (510, 520) for providing radiation for illuminating the seal (50) of the item (20), a detector (530, 540) for receiving radiation from the item (20) for generating a corresponding detected signal, and a processing arrangement (160) for processing the detected signal to generate an output signal indicative of a state of the seal (50). The radiation source (510, 520) is arranged to focus the radiation into a plurality of focal points at the seal (50) of the item (20), wherein the focal points are mutually spatially spaced apart. Moreover, the detector (530, 540) is arranged to image one or more of the focal points and to be selectively sensitive to an intensity of radiation received from the one or more focal points to generate a detected signal. Furthermore, the measuring apparatus (200) includes a processing arrangement (160) for receiving the detected signal and for processing the detected signal to generate the output signal indicative of the state of the seal (50).
Abstract:
A glucose sensor comprising an optical energy source having an emitter with an emission pattern; a first polarizer intersecting the emission pattern; a second polarizer spaced a distance from the first polarizer and intersecting the emission pattern, the second polarizer rotated relative to the first polarizer by a first rotational amount Θ; a first optical detector intersecting the emission pattern; a second optical detector positioned proximal to the second polarizer, the first polarizer and the second polarizer being positioned between the optical energy source and the second optical detector, the second optical detector intersecting the emission pattern; a compensating circuit coupled to the second optical detector; and a subtractor circuit coupled to the compensating circuit and the first optical detector.
Abstract:
A method for measuring second harmonic generation (SHG) scattered radiation from a sample including a turbid medium, providing a beam of laser pulses from a laser source having a high pulse energy of more than 10nJ and a repetition rate of less than 10 MHz; splitting the beam of laser pulses into two partial beams and focussing and overlaying the partial beams on a sample including the turbid medium; and detecting second harmonic radiation scattered from the sample.
Abstract:
A technique for determining whether or not a fluorescent material exhibits a directionally dependent property, such as anisotropy or chirality, involves illuminating the particle at its excitation wavelength to stimulate fluorescent emission at both a full-frequency (fundamental) wavelength and a half-frequency wavelength. The ratio of the full-frequency signal strength to the half-frequency signal strength provides an indication of the sample's directionally dependent property. This half-frequency spectral analysis can be used to sort anisotropic particles suspended in fluid flowing through a flow cytometer. For instance, the present technique may be used to separate racemic mixtures of chiral enantiomers of cells, pharmaceutical compounds, and other samples.
Abstract:
A pulse multiplier includes a polarizing beam splitter, a wave plate, and a set of mirrors. The polarizing beam splitter receives an input laser pulse. The wave plate receives light from the polarized beam splitter and generates a first set of pulses and a second set of pulses. The first set of pulses has a different polarization than the second set of pulses. The polarizing beam splitter, the wave plate, and the set of mirrors create a ring cavity. The polarizing beam splitter transmits the first set of pulses as an output of the pulse multiplier and reflects the second set of pulses into the ring cavity. This pulse multiplier can inexpensively reduce the peak power per pulse while increasing the number of pulses per second with minimal total power loss.
Abstract:
A non-invasive measurement of biological tissue reveals information about the function of that tissue. Polarized light is directed onto the tissue, stimulating the emission of fluorescence, due to one or more endogenous fluorophors in the tissue. Fluorescence anisotropy is then calculated. Such measurements of fluorescence anisotropy are then used to assess the functional status of the tissue, and to identify the existence and severity of disease states. Such assessment can be made by comparing a fluorescence anisotropy profile with a known profile of a control.
Abstract:
본 발명은 검출 장치 및 검출 방법을 제공한다. 검출 장치는 검출될 부품의 표면에 반사된 제 1 및 제 2 에코 광의 간섭에 의해 형성된 신호 광을 사용하여 제 1 검출 장치에 의해서 검출될 부품상의 샘플링 위치에 대응하는 신호 광의 제 1 광 세기 분포 정보를 얻고 세기 분포에 따라서 신호 광의 위상 분포를 얻고 검출될 부품의 결함 분포 데이터를 얻는다. 이들 중, 제 1 검출 기구는 2 개 초과의 편광 검출기 또는 비-편광 검출기 및 적어도 1 개의 편광 검출기를 포함한다. 본 발명은 신호 광의 편광 상태 분석을 효과적으로 달성하고, 종 방향으로 검출될 부품의 고정밀 검출을 달성하고, 우수한 신뢰성, 높은 안정성 및 신속한 검출 속도의 장점을 가질 수 있다.